AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms PE Morande, XJ Yan, J Sepulveda, N Seija, ME Marquez, N Sotelo, ... Blood, The Journal of the American Society of Hematology 138 (3), 246-258, 2021 | 13 | 2021 |
CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells SD Shafighi, SM Kiełbasa, J Sepúlveda-Yáñez, R Monajemi, D Cats, ... Genome medicine 13, 1-16, 2021 | 7 | 2021 |
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic … E Quinten, JH Sepúlveda-Yáñez, MT Koning, JA Eken, D Pfeifer, ... Haematologica 109 (3), 824, 2024 | 4 | 2024 |
Acquisition of a glycosylated B-cell receptor drives follicular lymphoma toward a dark zone phenotype CAM Van Bergen, SL Kloet, E Quinten, JH Sepúlveda Yáñez, R Menafra, ... Blood Advances 7 (19), 5812-5816, 2023 | 4 | 2023 |
Análisis del Estado de metilación del ADN y su relación con Modificaciones de Histonas del promotor de los Genes MLH1, p16 y NKX2-3, en diferentes tipos de cáncer JHS YÁÑEZ Universidad de Concepción, 2014 | 4 | 2014 |
High-Throughput BCR Sequencing and Single-Cell Transcriptomics Reveal Distinct Transcriptional Profiles Associated with Subclonal Evolution of Follicular Lymphoma CAM van Bergen, MT Koning, E Quinten, A Mykowiecka, J Sepulveda, ... Blood 134, 298, 2019 | 3 | 2019 |
The Antigen Receptor as a Driver of B-Cell Lymphoma Development and Evolution J Sepulveda, N Seija, P Oppezzo, MA Navarrete Hematology- Latest Research and Clinical Advances, 2017 | 3 | 2017 |
The mutation landscape of follicular lymphoma and chronic lymphocytic leukemia reveals a distinctive frequency and composition of AID-related mutation signatures J Sepulveda, CAM van Bergen, D Alvarez, S Kielbasa, H Mei, H Veelken, ... Blood 130, 2741, 2017 | 2 | 2017 |
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL JA Eken, MT Koning, K Kupcova, JH Sepúlveda Yáñez, RAL de Groen, ... Journal of Experimental Medicine 221 (5), 2024 | 1 | 2024 |
Autonomous BCR Signaling and Genetic Aberrations in CLL-Phenotype Monoclonal B Lymphocytosis in Siblings of CLL Patients JH Sepulveda Yanez, E Quinten, MT Koning, JA Eken, D Pfeifer, ... Blood 140 (Supplement 1), 1526-1527, 2022 | 1 | 2022 |
Tandem Substitutions in Somatic Hypermutation JH Sepúlveda-Yáñez, D Alvarez Saravia, B Pilzecker, ... Frontiers in Immunology 12, 807015, 2022 | 1 | 2022 |
Integration of Mutational Signature Analysis with 3D Chromatin Data Unveils Differential AID-Related Mutagenesis in Indolent Lymphomas JH Sepulveda-Yanez, D Alvarez-Saravia, J Fernandez-Goycoolea, ... International Journal of Molecular Sciences 22 (23), 13015, 2021 | 1 | 2021 |
Detection of Occurrent Somatic Hypermutation and Associated Gene Expression Profile in Single B Cells J Sepulveda-Yanez, D Alvarez-Saravia, D Medina, E Quinten, ... Blood 142, 4139, 2023 | | 2023 |
Artificial Intelligence Approach for the Discovery of Autoantigen Recognition By B-Cell Lymphomas D Medina, J Sepulveda-Yanez, D Alvarez-Saravia, R Uribe-Paredes, ... Blood 142, 125, 2023 | | 2023 |
B-Cell Receptor Function and Gene Expression Profiling at Single-Cell Level across the Spectrum from Normal to Neoplastic CD5-Positive B-Cell Compartments in Humans E Quinten, J Sepulveda-Yanez, R Monajemi, R Menafra, SL Kloet, ... Blood 142, 1885, 2023 | | 2023 |
Unbiased NGS Approach for IGHV Mutational Status, Clonal Space and Immune Repertoire Assessment in Chronic Lymphocytic Leukemia J Gonzalez-Puelma, J Sepulveda-Yanez, J Torres-Almonacid, ... Blood 140 (Supplement 1), 6979-6980, 2022 | | 2022 |
Antigen-Independent, Autonomous B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma JA Eken, MT Koning, JH Sepulveda Yanez, CAM van Bergen, E Quinten, ... Blood 140 (Supplement 1), 6444-6445, 2022 | | 2022 |
“Snapshotting” Somatic Hypermutation in Single Follicular Lymphoma Cells JH Sepulveda-Yanez, D Alvarez-Saravia, E Quinten, R Menafra, SL Kloet, ... Blood 138, 1151, 2021 | | 2021 |
Tandem Substitutions in Somatic Hypermutation MT Koning, JHS Yanez, D Alvarez-Saravia, B Pilzecker, ... Blood 138, 996, 2021 | | 2021 |
Differential Genome-Wide Mutational Patterns in Indolent B-Cell Lymphomas JHS Yanez, D Alvarez, J Fernandez-Goycoolea, CAM van Bergen, ... Blood 132, 4102, 2018 | | 2018 |