| Circulating tumor cell technologies MM Ferreira, VC Ramani, SS Jeffrey Molecular oncology 10 (3), 374-394, 2016 | 570 | 2016 |
| Heparanase regulates secretion, composition, and function of Tumor Cell-derived Exosomes*♦ CA Thompson, A Purushothaman, VC Ramani, I Vlodavsky, ... Journal of Biological Chemistry 288 (14), 10093-10099, 2013 | 354 | 2013 |
| Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-κB ligand pathway MS Bendre, AG Margulies, B Walser, NS Akel, S Bhattacharrya, ... Cancer research 65 (23), 11001-11009, 2005 | 284 | 2005 |
| SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis JP Ritchie, VC Ramani, Y Ren, A Naggi, G Torri, B Casu, S Penco, ... Clinical Cancer Research 17 (6), 1382-1393, 2011 | 282 | 2011 |
| Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior SK Bandari, A Purushothaman, VC Ramani, GJ Brinkley, ... Matrix biology 65, 104-118, 2018 | 224 | 2018 |
| The heparanase/syndecan‐1 axis in cancer: mechanisms and therapies VC Ramani, A Purushothaman, MD Stewart, CA Thompson, I Vlodavsky, ... The FEBS journal 280 (10), 2294-2306, 2013 | 218 | 2013 |
| Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E‐cadherin SK Johnson, VC Ramani, L Hennings, RS Haun Cancer 109 (9), 1811-1820, 2007 | 163 | 2007 |
| Heparanase is a host enzyme required for herpes simplex virus-1 release from cells SR Hadigal, AM Agelidis, GA Karasneh, TE Antoine, AM Yakoub, ... Nature communications 6 (1), 6985, 2015 | 141 | 2015 |
| Heparanase Plays a Dual Role in Driving Hepatocyte Growth Factor (HGF) Signaling by Enhancing HGF Expression and Activity*♦ VC Ramani, Y Yang, Y Ren, L Nan, RD Sanderson Journal of Biological Chemistry 286 (8), 6490-6499, 2011 | 133 | 2011 |
| Heparan sulfate chains of syndecan-1 regulate ectodomain shedding VC Ramani, PS Pruett, CA Thompson, LD DeLucas, RD Sanderson Journal of Biological Chemistry 287 (13), 9952-9961, 2012 | 132 | 2012 |
| Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer VC Ramani, L Hennings, RS Haun BMC cancer 8, 1-10, 2008 | 100 | 2008 |
| Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer E Kidess-Sigal, HE Liu, MM Triboulet, J Che, VC Ramani, BC Visser, ... Oncotarget 7 (51), 85349, 2016 | 89 | 2016 |
| Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma VC Ramani, F Zhan, J He, P Barbieri, A Noseda, G Tricot, RD Sanderson Oncotarget 7 (2), 1598, 2016 | 84 | 2016 |
| Chemotherapy induces expression and release of heparanase leading to changes associated with an aggressive tumor phenotype VC Ramani, I Vlodavsky, M Ng, Y Zhang, P Barbieri, A Noseda, ... Matrix biology 55, 22-34, 2016 | 83 | 2016 |
| Chemotherapy stimulates syndecan-1 shedding: a potentially negative effect of treatment that may promote tumor relapse VC Ramani, RD Sanderson Matrix Biology 35, 215-222, 2014 | 75 | 2014 |
| Heparanase enhances local and systemic osteolysis in multiple myeloma by upregulating the expression and secretion of RANKL Y Yang, Y Ren, VC Ramani, L Nan, LJ Suva, RD Sanderson Cancer research 70 (21), 8329-8338, 2010 | 74 | 2010 |
| The extracellular matrix protein fibronectin is a substrate for kallikrein 7 VC Ramani, RS Haun Biochemical and biophysical research communications 369 (4), 1169-1173, 2008 | 72 | 2008 |
| Shed syndecan-1 translocates to the nucleus of cells delivering growth factors and inhibiting histone acetylation: a novel mechanism of tumor-host cross-talk MD Stewart, VC Ramani, RD Sanderson Journal of Biological Chemistry 290 (2), 941-949, 2015 | 63 | 2015 |
| Fast and label-free isolation of circulating tumor cells from blood: from a research microfluidic platform to an automated fluidic instrument, VTX-1 liquid biopsy system CA Lemaire, SZ Liu, CL Wilkerson, VC Ramani, NA Barzanian, ... SLAS TECHNOLOGY: Translating Life Sciences Innovation 23 (1), 16-29, 2018 | 54 | 2018 |
| Proteolytic action of kallikrein-related peptidase 7 produces unique active matrix metalloproteinase-9 lacking the C-terminal hemopexin domains VC Ramani, GP Kaushal, RS Haun Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (8), 1525-1531, 2011 | 53 | 2011 |
