Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1404 | 2013 |
Toxicity Testing in the 21st Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways S Bhattacharya, Q Zhang, PL Carmichael, K Boekelheide, ME Andersen PloS one 6 (6), e20887, 2011 | 239 | 2011 |
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks Q Zhang, S Bhattacharya, ME Andersen Open biology 3 (4), 130031, 2013 | 190 | 2013 |
A deterministic map of Waddington's epigenetic landscape for cell fate specification S Bhattacharya, Q Zhang, ME Andersen BMC systems biology 5, 1-12, 2011 | 166 | 2011 |
A map of the PPARα transcription regulatory network for primary human hepatocytes PD McMullen, S Bhattacharya, CG Woods, B Sun, K Yarborough, ... Chemico-biological interactions 209, 14-24, 2014 | 121 | 2014 |
CATMoS: collaborative acute toxicity modeling suite K Mansouri, AL Karmaus, J Fitzpatrick, G Patlewicz, P Pradeep, D Alberga, ... Environmental health perspectives 129 (4), 047013, 2021 | 93 | 2021 |
Adaptive posttranslational control in cellular stress response pathways and its relationship to toxicity testing and safety assessment Q Zhang, S Bhattacharya, J Pi, RA Clewell, PL Carmichael, ME Andersen Toxicological Sciences 147 (2), 302-316, 2015 | 81 | 2015 |
Bridging the Data Gap From in vitro Toxicity Testing to Chemical Safety Assessment Through Computational Modeling Q Zhang, J Li, A Middleton, S Bhattacharya, RB Conolly Frontiers in public health 6, 261, 2018 | 75 | 2018 |
Modeling drug-and chemical-induced hepatotoxicity with systems biology approaches S Bhattacharya, LKM Shoda, Q Zhang, CG Woods, BA Howell, SQ Siler, ... Frontiers in physiology 3, 462, 2012 | 69 | 2012 |
Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses Q Zhang, S Bhattacharya, RB Conolly, HJ Clewell III, NE Kaminski, ... Environmental health perspectives 122 (12), 1261-1270, 2014 | 66 | 2014 |
Computational systems biology and dose-response modeling in relation to new directions in toxicity testing Q Zhang, S Bhattacharya, ME Andersen, RB Conolly Journal of Toxicology and Environmental Health, Part B 13 (2-4), 253-276, 2010 | 66 | 2010 |
Fractal dimensions of silica gels generated using reactive molecular dynamics simulations S Bhattacharya, J Kieffer The Journal of chemical physics 122 (9), 2005 | 55 | 2005 |
Single-nuclei RNA sequencing assessment of the hepatic effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin R Nault, KA Fader, S Bhattacharya, TR Zacharewski Cellular and Molecular Gastroenterology and Hepatology 11 (1), 147-159, 2021 | 53 | 2021 |
A Bistable Switch Underlying B-Cell Differentiation and Its Disruption by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-dioxin S Bhattacharya, RB Conolly, NE Kaminski, RS Thomas, ME Andersen, ... Toxicological sciences 115 (1), 51-65, 2010 | 50 | 2010 |
Molecular dynamics simulation study of growth regimes during polycondensation of silicic acid: from silica nanoparticles to porous gels S Bhattacharya, J Kieffer The Journal of Physical Chemistry C 112 (6), 1764-1771, 2008 | 48 | 2008 |
Aryl hydrocarbon receptor activation suppresses EBF1 and PAX5 and impairs human B lymphopoiesis J Li, S Bhattacharya, J Zhou, AS Phadnis-Moghe, RB Crawford, ... The Journal of Immunology 199 (10), 3504-3515, 2017 | 37 | 2017 |
A theoretical model of the Wnt signaling pathway in the epithelial mesenchymal transition K Gasior, M Hauck, A Wilson, S Bhattacharya Theoretical Biology and Medical Modelling 14, 1-20, 2017 | 31 | 2017 |
Pregnancy-specific physiologically-based toxicokinetic models for bisphenol A and bisphenol S J Gingrich, D Filipovic, R Conolly, S Bhattacharya, A Veiga-Lopez Environment international 147, 106301, 2021 | 27 | 2021 |
Stochastic modeling of B lymphocyte terminal differentiation and its suppression by dioxin Q Zhang, S Bhattacharya, DE Kline, RB Crawford, RB Conolly, ... BMC systems biology 4, 1-18, 2010 | 27 | 2010 |
Embracing systems toxicology at single-cell resolution Q Zhang, WM Caudle, J Pi, S Bhattacharya, ME Andersen, NE Kaminski, ... Current opinion in toxicology 16, 49-57, 2019 | 25 | 2019 |