Polycomb silencing blocks transcription initiation GI Dellino, YB Schwartz, G Farkas, D McCabe, SCR Elgin, V Pirrotta Molecular cell 13 (6), 887-893, 2004 | 356 | 2004 |
Genome-wide mapping of human DNA-replication origins: levels of transcription at ORC1 sites regulate origin selection and replication timing GI Dellino, D Cittaro, R Piccioni, L Luzi, S Banfi, S Segalla, M Cesaroni, ... Genome research 23 (1), 1-11, 2013 | 206 | 2013 |
In vivo functional platform targeting patient-derived xenografts identifies WDR5-Myc association as a critical determinant of pancreatic cancer A Carugo, G Genovese, S Seth, L Nezi, JL Rose, D Bossi, A Cicalese, ... Cell reports 16 (1), 133-147, 2016 | 135 | 2016 |
Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene TG Kahn, YB Schwartz, GI Dellino, V Pirrotta Journal of Biological Chemistry 281 (39), 29064-29075, 2006 | 124 | 2006 |
Pathology tissue–chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples M Fanelli, S Amatori, I Barozzi, M Soncini, R Dal Zuffo, G Bucci, M Capra, ... Proceedings of the National Academy of Sciences 107 (50), 21535-21540, 2010 | 123 | 2010 |
Genome-wide mapping of 8-oxo-7, 8-dihydro-2′-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of … S Amente, G Di Palo, G Scala, T Castrignanò, F Gorini, S Cocozza, ... Nucleic acids research 47 (1), 221-236, 2019 | 100 | 2019 |
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations GI Dellino, F Palluzzi, AM Chiariello, R Piccioni, S Bianco, L Furia, ... Nature genetics 51 (6), 1011-1023, 2019 | 98 | 2019 |
Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target MR Sapienza, F Abate, F Melle, S Orecchioni, F Fuligni, M Etebari, ... haematologica 104 (4), 729, 2019 | 76 | 2019 |
p53 loss in breast cancer leads to Myc activation, increased cell plasticity, and expression of a mitotic signature with prognostic value A Santoro, T Vlachou, L Luzi, G Melloni, L Mazzarella, E D’Elia, X Aobuli, ... Cell reports 26 (3), 624-638. e8, 2019 | 70 | 2019 |
In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype D Bossi, A Cicalese, GI Dellino, L Luzi, L Riva, C D'Alesio, GR Diaferia, ... Cancer discovery 6 (6), 650-663, 2016 | 70 | 2016 |
On the epigenetic role of guanosine oxidation M Giorgio, GI Dellino, V Gambino, PG Pelicci Redox Biology 29, 101398, 2020 | 57 | 2020 |
Exploiting the tunability of stimulated emission depletion microscopy for super-resolution imaging of nuclear structures MJ Sarmento, M Oneto, S Pelicci, L Pesce, L Scipioni, M Faretta, L Furia, ... Nature communications 9 (1), 1-11, 2018 | 51 | 2018 |
The genomic landscape of 8-oxodG reveals enrichment at specific inherently fragile promoters F Gorini, G Scala, G Di Palo, GI Dellino, S Cocozza, PG Pelicci, L Lania, ... Nucleic acids research 48 (8), 4309-4324, 2020 | 45 | 2020 |
WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells S Punzi, C Balestrieri, C D’Alesio, D Bossi, GI Dellino, E Gatti, G Pruneri, ... Breast Cancer Research 21, 1-18, 2019 | 34 | 2019 |
Cell cycle-dependent resolution of DNA double-strand breaks S Ambrosio, G Di Palo, G Napolitano, S Amente, GI Dellino, M Faretta, ... Oncotarget 7 (4), 4949, 2016 | 32 | 2016 |
Peak shape clustering reveals biological insights MA Cremona, LM Sangalli, S Vantini, GI Dellino, PG Pelicci, P Secchi, ... BMC bioinformatics 16, 1-18, 2015 | 29 | 2015 |
Nanoscale distribution of nuclear sites by super-resolved image cross-correlation spectroscopy M Oneto, L Scipioni, MJ Sarmento, I Cainero, S Pelicci, L Furia, PG Pelicci, ... Biophysical Journal 117 (11), 2054-2065, 2019 | 25 | 2019 |
Extensive conservation of sequences and chromatin structures in the bxd polycomb response element among Drosophilid species GI Dellino, C Tatout, V Pirrotta International Journal of Developmental Biology 46 (1), 133-142, 2002 | 24 | 2002 |
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups L Riva, C Ronchini, M Bodini, F Lo-Coco, S Lavorgna, T Ottone, ... Blood Cancer Journal 3 (9), e147-e147, 2013 | 23 | 2013 |
PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry A Palmigiano, F Santaniello, A Cerutti, D Penkov, D Purushothaman, ... Scientific Reports 8 (1), 3198, 2018 | 21 | 2018 |