Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence Y Tan, Z Zhang, C Zheng, KA Wintergerst, BB Keller, L Cai Nature Reviews Cardiology 17 (9), 585-607, 2020 | 468 | 2020 |
Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress–induced insulin resistance in cardiac cells in vitro and in vivo Y Tan, T Ichikawa, J Li, Q Si, H Yang, X Chen, CS Goldblatt, CJ Meyer, ... Diabetes 60 (2), 625-633, 2011 | 415 | 2011 |
Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation Y Bai, W Cui, Y Xin, X Miao, MT Barati, C Zhang, Q Chen, Y Tan, T Cui, ... Journal of molecular and cellular cardiology 57, 82-95, 2013 | 295 | 2013 |
Oxidative stress, diabetes, and diabetic complications W Wei, Q Liu, Y Tan, L Liu, X Li, L Cai Hemoglobin 33 (5), 370-377, 2009 | 253 | 2009 |
Acceleration of diabetic wound healing with chitosan-crosslinked collagen sponge containing recombinant human acidic fibroblast growth factor in healing-impaired STZ diabetic rats W Wang, S Lin, Y Xiao, Y Huang, Y Tan, L Cai, X Li Life sciences 82 (3-4), 190-204, 2008 | 214 | 2008 |
Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice Y Zhao, Y Tan, J Dai, B Li, L Guo, J Cui, G Wang, X Shi, X Zhang, ... Toxicology letters 200 (1-2), 100-106, 2011 | 199 | 2011 |
Cadmium and its epigenetic effects B Wang, Y Li, C Shao, Y Tan, L Cai Current medicinal chemistry 19 (16), 2611-2620, 2012 | 197 | 2012 |
Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways X Wang, X Chen, W Zhou, H Men, T Bao, Y Sun, Q Wang, Y Tan, ... Acta Pharmaceutica Sinica B 12 (2), 708-722, 2022 | 191 | 2022 |
Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway Z Zhang, S Wang, S Zhou, X Yan, Y Wang, J Chen, N Mellen, M Kong, ... Journal of Molecular and Cellular Cardiology 77, 42-52, 2014 | 191 | 2014 |
Role of iron deficiency and overload in the pathogenesis of diabetes and diabetic complications Q Liu, L Sun, Y Tan, G Wang, X Lin, L Cai Current medicinal chemistry 16 (1), 113-129, 2009 | 178 | 2009 |
Inactivation of GSK-3β by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling Y Wang, W Feng, W Xue, Y Tan, DW Hein, XK Li, L Cai Diabetes 58 (6), 1391-1402, 2009 | 176 | 2009 |
Metallothionein is downstream of Nrf2 and partially mediates sulforaphane prevention of diabetic cardiomyopathy J Gu, Y Cheng, H Wu, L Kong, S Wang, Z Xu, Z Zhang, Y Tan, BB Keller, ... Diabetes 66 (2), 529-542, 2017 | 154 | 2017 |
Prevention of diabetic nephropathy by sulforaphane: possible role of Nrf2 upregulation and activation W Cui, Y Bai, X Miao, P Luo, Q Chen, Y Tan, MJ Rane, L Miao, L Cai Oxidative medicine and cellular longevity 2012 (1), 821936, 2012 | 154 | 2012 |
Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy MJ Rane, YE Song, S Jin, MT Barati, R Wu, H Kausar, Y Tan, Y Wang, ... American Journal of Physiology-Renal Physiology 298 (1), F49-F61, 2010 | 152 | 2010 |
Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway Y Xin, Y Bai, X Jiang, S Zhou, Y Wang, KA Wintergerst, T Cui, H Ji, Y Tan, ... Redox Biology 15, 405-417, 2018 | 150 | 2018 |
Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice J Zhang, Y Cheng, J Gu, S Wang, S Zhou, Y Wang, Y Tan, W Feng, Y Fu, ... Clinical science 130 (8), 625-641, 2016 | 150 | 2016 |
Nrf2: redox and metabolic regulator of stem cell state and function X Dai, X Yan, KA Wintergerst, L Cai, BB Keller, Y Tan Trends in Molecular Medicine 26 (2), 185-200, 2020 | 147 | 2020 |
Elevating CXCR7 improves angiogenic function of EPCs via Akt/GSK-3β/Fyn-mediated Nrf2 activation in diabetic limb ischemia X Dai, X Yan, J Zeng, J Chen, Y Wang, J Chen, Y Li, MT Barati, ... Circulation research 120 (5), e7-e23, 2017 | 142 | 2017 |
Minireview: roles of fibroblast growth factors 19 and 21 in metabolic regulation and chronic diseases F Zhang, L Yu, X Lin, P Cheng, L He, X Li, X Lu, Y Tan, H Yang, L Cai, ... Molecular endocrinology 29 (10), 1400-1413, 2015 | 134 | 2015 |
Berberine attenuates hepatic steatosis and enhances energy expenditure in mice by inducing autophagy and fibroblast growth factor 21 Y Sun, M Xia, H Yan, Y Han, F Zhang, Z Hu, A Cui, F Ma, Z Liu, Q Gong, ... British journal of pharmacology 175 (2), 374-387, 2018 | 131 | 2018 |