Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery DJ Siegwart, KA Whitehead, L Nuhn, G Sahay, H Cheng, S Jiang, M Ma, ... Proceedings of the National Academy of Sciences 108 (32), 12996-13001, 2011 | 267 | 2011 |
pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation L Nuhn, N Vanparijs, A De Beuckelaer, L Lybaert, G Verstraete, ... Proceedings of the National Academy of Sciences 113 (29), 8098-8103, 2016 | 196 | 2016 |
Cationic nanohydrogel particles as potential siRNA carriers for cellular delivery L Nuhn, M Hirsch, B Krieg, K Koynov, K Fischer, M Schmidt, M Helm, ... Acs Nano 6 (3), 2198-2214, 2012 | 148 | 2012 |
Nanoparticle‐Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses L Nuhn, S De Koker, S Van Lint, Z Zhong, JP Catani, F Combes, ... Advanced Materials 30 (45), 1803397, 2018 | 135 | 2018 |
Transiently thermoresponsive polymers and their applications in biomedicine N Vanparijs, L Nuhn, BG De Geest Chemical Society Reviews 46 (4), 1193-1239, 2017 | 134 | 2017 |
Water-soluble polymers coupled with glycopeptide antigens and T-cell epitopes as potential antitumor vaccines. L Nuhn, S Hartmann, B Palitzsch, B Gerlitzki, E Schmitt, R Zentel, H Kunz Angewandte Chemie International Edition 52 (40), 2013 | 105 | 2013 |
pH-degradable mannosylated nanogels for dendritic cell targeting R De Coen, N Vanparijs, MDP Risseeuw, L Lybaert, B Louage, ... Biomacromolecules 17 (7), 2479-2488, 2016 | 80 | 2016 |
The protein corona as a confounding variable of nanoparticle-mediated targeted vaccine delivery M Bros, L Nuhn, J Simon, L Moll, V Mailänder, K Landfester, S Grabbe Frontiers in immunology 9, 1760, 2018 | 79 | 2018 |
Aggregation behavior of cationic nanohydrogel particles in human blood serum L Nuhn, S Gietzen, K Mohr, K Fischer, K Toh, K Miyata, Y Matsumoto, ... Biomacromolecules 15 (4), 1526-1533, 2014 | 75 | 2014 |
SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles N Leber, L Kaps, M Aslam, J Schupp, A Brose, D Schäffel, K Fischer, ... Journal of Controlled Release 248, 10-23, 2017 | 67 | 2017 |
Size-dependent knockdown potential of siRNA-loaded cationic nanohydrogel particles L Nuhn, S Tomcin, K Miyata, V Mailänder, K Landfester, K Kataoka, ... Biomacromolecules 15 (11), 4111-4121, 2014 | 66 | 2014 |
New Perspectives of HPMA‐based Copolymers Derived by Post‐Polymerization Modification L Nuhn, M Barz, R Zentel Macromolecular bioscience 14 (5), 607-618, 2014 | 66 | 2014 |
Well‐Defined Polymer–Paclitaxel Prodrugs by a Grafting‐from‐Drug Approach B Louage, L Nuhn, MDP Risseeuw, N Vanparijs, R De Coen, I Karalic, ... Angewandte Chemie International Edition 55 (39), 11791-11796, 2016 | 63 | 2016 |
Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist L Nuhn, L Van Hoecke, K Deswarte, B Schepens, Y Li, BN Lambrecht, ... Biomaterials 178, 643-651, 2018 | 60 | 2018 |
Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through strain promoted azide alkyne cycloaddition ligation L Nuhn, E Bolli, S Massa, I Vandenberghe, K Movahedi, B Devreese, ... Bioconjugate chemistry 29 (7), 2394-2405, 2018 | 59 | 2018 |
CpG-loaded multifunctional cationic nanohydrogel particles as self-adjuvanting glycopeptide antitumor vaccines. S Hartmann, L Nuhn, B Palitzsch, M Glaffig, N Stergiou, B Gerlitzki, ... Advanced healthcare materials 4 (4), 522-527, 2014 | 57 | 2014 |
A fully synthetic glycopeptide antitumor vaccine based on multiple antigen presentation on a hyperbranched polymer M Glaffig, B Palitzsch, S Hartmann, C Schüll, L Nuhn, B Gerlitzki, ... Chemistry–A European Journal 20 (15), 4232-4236, 2014 | 56 | 2014 |
Supramolecular Linear-g-Hyperbranched Graft Polymers: Topology and Binding Strength of Hyperbranched Side Chains C Moers, L Nuhn, M Wissel, R Stangenberg, M Mondeshki, ... Macromolecules 46 (24), 9544-9553, 2013 | 55 | 2013 |
Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine S Jangra, J De Vrieze, A Choi, R Rathnasinghe, G Laghlali, A Uvyn, ... Angewandte Chemie International Edition 60 (17), 9467-9473, 2021 | 53 | 2021 |
DNA–Polymer Nanostructures by RAFT Polymerization and Polymerization‐Induced Self‐Assembly T Lückerath, K Koynov, S Loescher, CJ Whitfield, L Nuhn, A Walther, ... Angewandte Chemie International Edition 59 (36), 15474-15479, 2020 | 52 | 2020 |