Ageing and the telomere connection: An intimate relationship with inflammation J Zhang, G Rane, X Dai, MK Shanmugam, F Arfuso, RP Samy, MKP Lai, ... Ageing Research Reviews 25, 55-69, 2016 | 374 | 2016 |
Regional Multiple Pathology Scores Are Associated with Cognitive Decline in L ewy Body Dementias DR Howlett, D Whitfield, M Johnson, J Attems, JT O'Brien, D Aarsland, ... Brain Pathology 25 (4), 401-408, 2015 | 200 | 2015 |
Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease MKP Lai, SWY Tsang, PT Francis, MM Esiri, J Keene, T Hope, ... Brain Research 974 (1-2), 82-87, 2003 | 192 | 2003 |
Psychosis of Alzheimer’s disease is associated with elevated muscarinic M2 binding in the cortex MK P. Lai, OF Lai, J Keene, MM Esiri, PT Francis, T Hope, CPLH Chen Neurology 57 (5), 805-811, 2001 | 156 | 2001 |
Neurochemical basis for symptomatic treatment of Alzheimer's disease PT Francis, MJ Ramírez, MK Lai Neuropharmacology 59 (4-5), 221-229, 2010 | 146 | 2010 |
Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR) X Gallart-Palau, A Serra, ASW Wong, S Sandin, MKP Lai, CP Chen, ... Scientific Reports 5, 14664, 2015 | 131 | 2015 |
Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease MG Tan, WT Chua, MM Esiri, AD Smith, HV Vinters, MK Lai Journal of Neuroscience Research 88 (6), 1157-1169, 2010 | 131 | 2010 |
Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer’s disease MK Lai, SW Tsang, JT Alder, J Keene, T Hope, MM Esiri, PT Francis, ... Psychopharmacology 179 (3), 673-677, 2005 | 129 | 2005 |
Impaired coupling of muscarinic M1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease SWY Tsang, MKP Lai, S Kirvell, PT Francis, MM Esiri, T Hope, ... Neurobiology of Aging 27 (9), 1216-1223, 2006 | 116 | 2006 |
Involvement of the GABAergic system in depressive symptoms of Alzheimer's disease M Garcia-Alloza, SW Tsang, FJ Gil-Bea, PT Francis, MK Lai, B Marcos, ... Neurobiology of Aging 27 (8), 1110-1117, 2006 | 108 | 2006 |
Postmortem serotoninergic correlates of cognitive decline in Alzheimer's disease MKP Lai, SWY Tsang, PT Francis, J Keene, T Hope, MM Esiri, I Spence, ... Neuroreport 13 (9), 1175-1178, 2002 | 105 | 2002 |
Serotonergic therapies for cognitive symptoms in Alzheimer’s disease: rationale and current status MJ Ramirez, MKP Lai, RM Tordera, PT Francis Drugs 74 (7), 729-736, 2014 | 96 | 2014 |
Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment V Rajeev, DY Fann, QN Dinh, HA Kim, TM De Silva, MKP Lai, CLH Chen, ... Theranostics 12 (4), 1639, 2022 | 95 | 2022 |
The brain lipidomes of subcortical ischemic vascular dementia and mixed dementia SM Lam, Y Wang, X Duan, MR Wenk, RN Kalaria, CP Chen, MKP Lai, ... Neurobiology of Aging 35 (10), 2369-2381, 2014 | 93 | 2014 |
AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia L Poh, DY Fann, P Wong, HM Lim, SL Foo, SW Kang, V Rajeev, ... Molecular Psychiatry 26 (8), 4544-4560, 2021 | 90 | 2021 |
F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy ZD Zhou, SP Xie, S Sathiyamoorthy, WT Saw, TY Sing, SH Ng, HPH Chua, ... Human Molecular Genetics 24 (22), 6314-6330, 2015 | 85 | 2015 |
Andrographolide induces Nrf2 and heme oxygenase 1 in astrocytes by activating p38 MAPK and ERK SY Wong, MGK Tan, PTH Wong, DR Herr, MKP Lai Journal of Neuroinflammation 13 (1), 251, 2016 | 79 | 2016 |
Markers of cardiac dysfunction in cognitive impairment and dementia S Hilal, YL Chai, MK Ikram, S Elangovan, TB Yeow, X Xin, JY Chong, ... Medicine 94 (1), e297, 2015 | 78 | 2015 |
Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex JH Lee, G Agacinski, JH Williams, GK Wilcock, MM Esiri, PT Francis, ... Neurochemistry International 57 (8), 985-989, 2010 | 78 | 2010 |
Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer’s disease with cerebrovascular disease X Gallart-Palau, BST Lee, SS Adav, J Qian, A Serra, JE Park, MKP Lai, ... Molecular Brain 9, 27, 2016 | 68 | 2016 |