Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence MR Spalinger, A Shawki, P Chatterjee, V Canale, A Santos, ... Gut 71 (1), 89-99, 2022 | 17 | 2022 |
The autoimmune susceptibility gene, PTPN2, restricts expansion of a novel mouse adherent-invasive E. coli A Shawki, R Ramirez, MR Spalinger, PM Ruegger, A Sayoc-Becerra, ... Gut Microbes 11 (6), 1547-1566, 2020 | 17 | 2020 |
Loss of protein tyrosine phosphatase non-receptor type 2 reduces IL-4-driven alternative macrophage activation MR Spalinger, M Crawford, SD Bobardt, J Li, A Sayoc-Becerra, AN Santos, ... Mucosal immunology 15 (1), 74-83, 2022 | 12 | 2022 |
PTPN2 is a critical regulator of ileal Paneth cell viability and function in mice V Canale, MR Spalinger, R Alvarez, A Sayoc-Becerra, G Sanati, S Manz, ... Cellular and Molecular Gastroenterology and Hepatology 16 (1), 39-62, 2023 | 4 | 2023 |
Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfα expression, gut barrier dysfunction, and endotoxemia in mice MS Crawford, A Ulu, BM Ramirez, AN Santos, P Chatterjee, V Canale, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 326 (1 …, 2024 | 1 | 2024 |
217: PTPN2 LOSS-OF-FUNCTION REDUCES VITAMIN B12 LEVELS IN GENOTYPED CROHN'S DISEASE PATIENTS AND INTESTINAL BRUSH BORDER EXPRESSION OF THE B12 TRANSPORTER, CUBILIN, IN MICE SM Manz, V Canale, SC Meli'sa, P Chaterjee, A Lei, AN Santos, A Shawki, ... Gastroenterology 162 (7), S-39, 2022 | 1 | 2022 |
The IBD Risk gene, PTPN2, Is Required for Commensal-associated Th17 Responses to Protect Against Pathobiont Colonization N Saad, P Chatterjee, V Canale, RR Marchelletta, A Shawki, DF McCole Physiology 39 (S1), 1247, 2024 | | 2024 |
RESPIRATORY EXPOSURE TO AGRICULTURAL DUST EXTRACT PROMOTES 1 INCREASED INTESTINAL Tnfα EXPRESSION, GUT BARRIER DYSFUNCTION, 2 AND ENDOTOXEMIA IN MICE 3 S Meli’sa, A Ulu, BM Ramirez, AN Santos, P Chatterjee, V Canale, ... American journal of physiology. Gastrointestinal and liver physiology 326 (1 …, 2024 | | 2024 |
Intestinal Epithelial Cell PTPN2 Restricts Intestinal Permeability and Tight-Junction Remodelling Caused by Adherent-invasive E. coli in Mice P Chatterjee, M Spalinger, A Shawki, A Santos, A Sayoc, H Lei, S Manz, ... Physiology 38 (S1), 5734009, 2023 | | 2023 |
Constitutive Loss of Ptpn2 in Mice Causes Features of Anemia Including Iron Deficiency H Lei, A Shawki, M Spalinger, V Canale, A Santos, P Chatterjee, ... Physiology 38 (S1), 5725802, 2023 | | 2023 |
556 INTESTINAL EPITHELIAL PTPN2 RESTRICTS ADHERENT-INVASIVE E. COLI COLONIZATION AND PROMOTES IL-22 PRODUCTION IN MICE P Chatterjee, M Spalinger, A Shawki, SM Manz, AN Santos, A Sayoc, ... Gastroenterology 164 (6), S-97, 2023 | | 2023 |
PTPN2 regulates bacterial clearance in a mouse model of enteropathogenic and enterohemorrhagic E. coli infection MR Spalinger, V Canale, A Becerra, A Shawki, AN Santos, P Chatterjee, ... JCI insight 8 (4), 2023 | | 2023 |
Role of Autoimmune Susceptibility Gene, PTPN2, in Mediating Host-Pathobiont Interaction P Chatterjee University of California, Riverside, 2023 | | 2023 |
Intestinal Epithelial PTPN2 Restricts Adherent‐Invasive E. coli Colonization and Promotes Anti‐Microbial Peptide Responses in Mice P Chatterjee, M Spalinger, A Shawki, A Santos, C Gries, A Sayoc, ... The FASEB Journal 36, 2022 | | 2022 |
Loss of PTPN2 Activity Alters Iron Handling Protein Expression in IBD Patients and Causes Iron Deficiency in Mice H Lei, A Shawki, MR Spalinger, V Canale, AN Santos, P Chatterjee, ... The FASEB Journal 36, 2022 | | 2022 |
Loss of PTPN2 in Intestinal Epithelial Cells Increases Invasion of Human Intestinal Epithelial Cells and Intestinal Permeability in Mice by Adherent‐invasive E. coli P Chatterjee, M Spalinger, A Shawki, C Gries, A Sayoc, A Santos, ... The FASEB Journal 35, 2021 | | 2021 |
Fr457 THE IBD-CANDIDATE GENE, PTPN2, IS A KEY REGULATOR OF ILEAL PANETH CELL FUNCTION IN MICE. V Canale, P Chaterjee, A Sayoc, AN Santos, M Spalinger, A Shawki, ... Gastroenterology 160 (6), S-324, 2021 | | 2021 |
28 LOSS OF PTPN2 COMPROMISES THE ABILITY OF MACROPHAGES TI CLEAR ADHERENT-INVASIVE E. COLI M Spalinger, A Shawki, P Chatterjee, V Canale, AN Santos, A Sayoc, ... Gastroenterology 160 (6), S-7, 2021 | | 2021 |
619 A LOSS OF FUNCTION SNP IN THE PTPN2 GENE IN IBD PATIENT-DERIVED MACROPHAGES PROMOTES AIEC INFECTION AND COMPROMISES AUTOPHAGY AND LYSOSOME-DEPENDENT BACTERIAL CLEARANCE M Spalinger, A Shawki, P Chatterjee, AN Santos, A Sayoc, S Lang, ... Gastroenterology 158 (6), S-133, 2020 | | 2020 |
The IBD candidate gene, PTPN2, Restricts Epithelial and Macrophage Invasion of a Novel Reporter Adherent‐Invasive Escherichia coli P Chatterjee, M Spalinger, C Gries, A Shawki, J Borneman, D McCole The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |