Decreased consumption of branched-chain amino acids improves metabolic health L Fontana, NE Cummings, SIA Apelo, JC Neuman, I Kasza, BA Schmidt, ... Cell reports 16 (2), 520-530, 2016 | 426 | 2016 |
Restoration of metabolic health by decreased consumption of branched‐chain amino acids NE Cummings, EM Williams, I Kasza, EN Konon, MD Schaid, BA Schmidt, ... The Journal of physiology 596 (4), 623-645, 2018 | 305 | 2018 |
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine D Yu, NE Richardson, CL Green, AB Spicer, ME Murphy, V Flores, C Jang, ... Cell metabolism 33 (5), 905-922. e6, 2021 | 249 | 2021 |
Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and life span in mice NE Richardson, EN Konon, HS Schuster, AT Mitchell, C Boyle, ... Nature Aging 1 (1), 73-86, 2021 | 192 | 2021 |
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system SI Arriola Apelo, JC Neuman, EL Baar, FA Syed, NE Cummings, HK Brar, ... Aging cell 15 (1), 28-38, 2016 | 180 | 2016 |
Intermittent administration of rapamycin extends the life span of female C57BL/6J mice SI Arriola Apelo, CP Pumper, EL Baar, NE Cummings, DW Lamming Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 129 | 2016 |
Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice HH Pak, SA Haws, CL Green, M Koller, MT Lavarias, NE Richardson, ... Nature Metabolism 3 (10), 1327-1341, 2021 | 108 | 2021 |
Central nervous system regulation of organismal energy and glucose homeostasis MG Myers Jr, AH Affinati, N Richardson, MW Schwartz Nature Metabolism 3 (6), 737-750, 2021 | 81 | 2021 |
Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms D Yu, SE Yang, BR Miller, JA Wisinski, DS Sherman, JA Brinkman, ... The FASEB Journal 32 (6), 3471, 2018 | 81 | 2018 |
Calorie-restriction-induced insulin sensitivity is mediated by adipose mTORC2 and not required for lifespan extension D Yu, JL Tomasiewicz, SE Yang, BR Miller, MH Wakai, DS Sherman, ... Cell reports 29 (1), 236-248. e3, 2019 | 76 | 2019 |
Restriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft model DW Lamming, NE Cummings, AL Rastelli, F Gao, E Cava, B Bertozzi, ... Oncotarget 6 (31), 31233, 2015 | 75 | 2015 |
Regulation of metabolic health and aging by nutrient-sensitive signaling pathways NE Cummings, DW Lamming Molecular and cellular endocrinology 455, 13-22, 2017 | 66 | 2017 |
Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction CL Green, HH Pak, NE Richardson, V Flores, D Yu, JL Tomasiewicz, ... Cell metabolism 34 (2), 209-226. e5, 2022 | 52 | 2022 |
Protein restriction and branched‐chain amino acid restriction promote geroprotective shifts in metabolism ME Trautman, NE Richardson, DW Lamming Aging cell 21 (6), e13626, 2022 | 40 | 2022 |
Decoding perineuronal net glycan sulfation patterns in the Alzheimer's disease brain AF Logsdon, KL Francis, NE Richardson, SJ Hu, CL Faber, BA Phan, ... Alzheimer's & Dementia 18 (5), 942-954, 2022 | 36 | 2022 |
Ovariectomy uncouples lifespan from metabolic health and reveals a sex-hormone-dependent role of hepatic mTORC2 in aging SI Arriola Apelo, A Lin, JA Brinkman, E Meyer, M Morrison, ... Elife 9, e56177, 2020 | 29 | 2020 |
Proposal of a new model for CL regression or maintenance during pregnancy on the basis of timing of regression of contralateral, accessory CL in pregnant cows GM Baez, E Trevisol, RV Barletta, BO Cardoso, A Ricci, JN Guenther, ... Theriogenology 89, 214-225, 2017 | 29 | 2017 |
Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission JM Brown, MA Bentsen, DM Rausch, BA Phan, D Wieck, H Wasanwala, ... IScience 24 (9), 2021 | 23 | 2021 |
The metabolic response to a low amino acid diet is independent of diet-induced shifts in the composition of the gut microbiome HH Pak, NE Cummings, CL Green, JA Brinkman, D Yu, JL Tomasiewicz, ... Scientific reports 9 (1), 67, 2019 | 22 | 2019 |
Age-dependent protection of insulin secretion in diet induced obese mice ER De Leon, JA Brinkman, RJ Fenske, T Gregg, BA Schmidt, ... Scientific reports 8 (1), 17814, 2018 | 22 | 2018 |