Regulation of signaling and metabolism by lipin-mediated phosphatidic acid phosphohydrolase activity AJ Lutkewitte, BN Finck Biomolecules 10 (10), 1386, 2020 | 37 | 2020 |
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids MR Martino, M Gutiérrez-Aguilar, NKH Yiew, AJ Lutkewitte, JM Singer, ... Cell reports 39 (4), 2022 | 33 | 2022 |
Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration AJ Lutkewitte, GG Schweitzer, S Kennon-McGill, MM Clemens, LP James, ... Food and Chemical Toxicology 115, 273-283, 2018 | 29 | 2018 |
Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism D Ferguson, SJ Eichler, NKH Yiew, JR Colca, K Cho, GJ Patti, TM Shew, ... Molecular metabolism 70, 101694, 2023 | 26 | 2023 |
Monoacylglycerol acyltransferase 1 knockdown exacerbates hepatic ischemia/reperfusion injury in mice with hepatic steatosis KHH Liss, SE Ek, AJ Lutkewitte, TA Pietka, M He, P Skaria, E Tycksen, ... Liver Transplantation 27 (1), 116-133, 2021 | 15 | 2021 |
Hepatic monoacylglycerol acyltransferase 1 is induced by prolonged food deprivation to modulate the hepatic fasting response [S] AJ Lutkewitte, KS McCommis, GG Schweitzer, KT Chambers, MJ Graham, ... Journal of lipid research 60 (3), 528-538, 2019 | 15 | 2019 |
Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1 AJ Lutkewitte, JM Singer, TM Shew, MR Martino, AM Hall, M He, BN Finck Molecular Metabolism 49, 101204, 2021 | 11 | 2021 |
Mitochondrial pyruvate carrier inhibition in hepatic stellate cells attenuates fibrosis in nonalcoholic steatohepatitis in mice D Ferguson, M Habibi, SJ Eichler, A LaPoint, TM Shew, M He, ... bioRxiv, 2023.02. 13.528384, 2023 | 7* | 2023 |
Monoacylglycerol O‐acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice JM Singer, TM Shew, D Ferguson, MK Renkemeyer, TA Pietka, AM Hall, ... Obesity 30 (11), 2122-2133, 2022 | 3 | 2022 |
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice NKH Yiew, S Deja, D Ferguson, K Cho, C Jarasvaraparn, M Jacome-Sosa, ... Iscience 26 (11), 2023 | 2 | 2023 |
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice NKH Yiew, S Deja, D Ferguson, K Cho, C Jarasvaraparn, M Jacome-Sosa, ... bioRxiv, 2023 | 2 | 2023 |
Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice A LaPoint, JM Singer, D Ferguson, TM Shew, MK Renkemeyer, ... bioRxiv, 2023.02. 01.526676, 2023 | 2 | 2023 |
VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism R Kumari, ME Ponte, E Franczak, JC Prom, MF O'Neil, ME Sardiu, ... Molecular Metabolism 82, 101908, 2024 | 1 | 2024 |
Dynamic changes in the mouse hepatic lipidome following warm ischemia reperfusion injury KHH Liss, M Mousa, S Bucha, A Lutkewitte, J Allegood, LA Cowart, ... Scientific reports 14 (1), 3584, 2024 | 1 | 2024 |
Ube4A maintains metabolic homeostasis and facilitates insulin signaling in vivo S Mukherjee, M Chakraborty, EN Msengi, J Haubner, J Zhang, ... Molecular Metabolism 75, 101767, 2023 | 1 | 2023 |
1575-P: Glycerol Metabolism and Gluconeogenesis in Mice Lacking the Mitochondrial Pyruvate Carrier in Hepatocytes N YIEW, D FERGUSON, K CHO, S DEJA, C JARASVARAPARN, X FU, ... Diabetes 72 (Supplement_1), 2023 | 1 | 2023 |
Glucolipotoxic Stress-Induced Mig6 Desensitizes EGFR Signaling and Promotes Pancreatic Beta Cell Death YC Chen, AJ Lutkewitte, HD Basavarajappa, PT Fueger Metabolites 13 (5), 627, 2023 | 1 | 2023 |
Regulation of PGC1α downstream of the insulin signaling pathway plays a role in the hepatic proteotoxicity of mutant α1-antitrypsin deficiency variant Z DA Rudnick, J Huang, T Hidvegi, AS Chu, P Hale, A Munanairi, ... Gastroenterology 163 (1), 270-284, 2022 | 1 | 2022 |
Glucolipotoxicity-induced Mig6 desensitizes EGFR signaling and promotes pancreatic beta cell death YC Chen, AJ Lutkewitte, HD Basavarajappa, PT Fueger bioRxiv, 2020.11. 24.380279, 2020 | 1 | 2020 |
Monoacylglycerol O-acyltransferase 1 is required for adipocyte differentiation in vitro but does not affect adiposity in mice JM Singer, TM Shew, D Ferguson, MK Renkemeyer, TA Pietka, AM Hall, ... bioRxiv, 2022.02. 14.480414, 2022 | | 2022 |