Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT KB Leszczynska, IP Foskolou, AG Abraham, S Anbalagan, C Tellier, ... The Journal of clinical investigation 125 (6), 2385-2398, 2015 | 138 | 2015 |
Replication stress and chromatin context link ATM activation to a role in DNA replication MM Olcina, IP Foskolou, S Anbalagan, JM Senra, IM Pires, Y Jiang, ... Molecular cell 52 (5), 758-766, 2013 | 124 | 2013 |
Ribonucleotide reductase requires subunit switching in hypoxia to maintain DNA replication IP Foskolou, C Jorgensen, KB Leszczynska, MM Olcina, H Tarhonskaya, ... Molecular cell 66 (2), 206-220. e9, 2017 | 83 | 2017 |
Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A IP Foskolou, D Stellas, I Rozani, MD Lavigne, PK Politis Oncogene 32 (8), 947-960, 2013 | 53 | 2013 |
Challenges to DNA replication in hypoxic conditions N Ng, K Purshouse, IP Foskolou, MM Olcina, EM Hammond The FEBS journal 285 (9), 1563-1571, 2018 | 52 | 2018 |
Modified Hypoxia-Inducible Factor Expression in CD8+ T Cells Increases Antitumor Efficacy P Veliça, PP Cunha, N Vojnovic, IP Foskolou, D Bargiela, M Gojkovic, ... Cancer immunology research 9 (4), 401-414, 2021 | 35 | 2021 |
Oxygen regulation of TET enzymes R Matuleviciute, PP Cunha, RS Johnson, IP Foskolou The FEBS Journal, 2021 | 34 | 2021 |
Hypoxia-induced SETX links replication stress with the unfolded protein response S Ramachandran, T Ma, N Ng, I Foskolou, MS Hwang, P Victori, ... Nature Communications 12 (3686), 2021 | 28 | 2021 |
The S enantiomer of 2-hydroxyglutarate increases central memory CD8 populations and improves CAR-T therapy outcome IP Foskolou, L Barbieri, A Vernet, D Bargiela, PP Cunha, P Velica, E Suh, ... Blood Advances 4 (18), 4483-4493, 2020 | 26 | 2020 |
Glutarate regulates T cell metabolism and anti-tumour immunity E Minogue, PP Cunha, BJ Wadsworth, GL Grice, SK Sah-Teli, R Hughes, ... Nature Metabolism 5 (10), 1747-1764, 2023 | 15* | 2023 |
Vitamin B6 metabolism determines T cell anti-tumor responses D Bargiela, PP Cunha, P Veliça, IP Foskolou, L Barbieri, H Rundqvist, ... Frontiers in Immunology 13, 837669, 2022 | 15 | 2022 |
Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells L Barbieri, P Veliça, PA Gameiro, PP Cunha, IP Foskolou, E Rullman, ... Frontiers in Immunology 14, 1101433, 2023 | 13 | 2023 |
Prox1 inhibits neurite outgrowth during central nervous system development V Kaltezioti, IP Foskolou, MD Lavigne, E Ninou, M Tsampoula, M Fousteri, ... Cellular and Molecular Life Sciences 78, 3443-3465, 2021 | 13 | 2021 |
Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy PP Cunha, E Minogue, LCM Krause, RM Hess, D Bargiela, BJ Wadsworth, ... Elife 12, e84280, 2023 | 12 | 2023 |
The Debaryomyces hansenii carboxylate transporters Jen1 homologues are functional in Saccharomyces cerevisiae I Soares-Silva, D Ribas, IP Foskolou, B Barata, D Bessa, S Paiva, ... FEMS Yeast Research 15 (8), fov094, 2015 | 12 | 2015 |
Lactate potentiates differentiation and expansion of cytotoxic T cells H Rundqvist, P Veliça, L Barbieri, PA Gameiro, PP Cunha, M Gojkovic, ... BioRxiv, 571745, 2019 | 10 | 2019 |
Measuring DNA replication in hypoxic conditions IP Foskolou, D Biasoli, MM Olcina, EM Hammond Tumor Microenvironment: Study Protocols, 11-25, 2016 | 7 | 2016 |
The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function IP Foskolou, PP Cunha, E Sánchez-López, EA Minogue, BP Nicolet, ... Cell reports 42 (9), 2023 | 5 | 2023 |
RRM2B: An oxygen-requiring protein with a role in hypoxia IP Foskolou, EM Hammond Molecular & Cellular Oncology 4 (5), e1335272, 2017 | 5 | 2017 |
2-hydroxyglutarate rides the cancer-immunity cycle IP Foskolou, L Bunse, J Van den Bossche Current opinion in biotechnology 83, 102976, 2023 | 3 | 2023 |