Structural alterations of the epidermal growth factor receptor gene in human gliomas. AJ Wong, JM Ruppert, SH Bigner, CH Grzeschik, PA Humphrey, ... Proceedings of the National Academy of Sciences 89 (7), 2965-2969, 1992 | 1104 | 1992 |
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. AJ Wong, SH Bigner, DD Bigner, KW Kinzler, SR Hamilton, B Vogelstein Proceedings of the National Academy of Sciences 84 (19), 6899-6903, 1987 | 1055 | 1987 |
Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors DK Moscatello, M Holgado-Madruga, AK Godwin, G Ramirez, G Gunn, ... Cancer research 55 (23), 5536-5539, 1995 | 871 | 1995 |
Identification of an amplified, highly expressed gene in a human glioma KW Kinzler, SH Bigner, DD Bigner, JM Trent, ML Law, SJ O'Brien, ... Science 236 (4797), 70-73, 1987 | 871 | 1987 |
A Grb2-associated docking protein in EGF-and insulin-receptor signalling M Holgado-Madruga, DR Emlet, DK Moscatello, AK Godwin, AJ Wong Nature 379 (6565), 560-564, 1996 | 847 | 1996 |
Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas CJ Wikstrand, LP Hale, SK Batra, ML Hill, PA Humphrey, SN Kurpad, ... Cancer research 55 (14), 3140-3148, 1995 | 650 | 1995 |
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma. PA Humphrey, AJ Wong, B Vogelstein, MR Zalutsky, GN Fuller, GE Archer, ... Proceedings of the National Academy of Sciences 87 (11), 4207-4211, 1990 | 476 | 1990 |
Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway I Okamoto, Y Kawano, D Murakami, T Sasayama, N Araki, T Miki, ... The Journal of cell biology 155 (5), 755-762, 2001 | 467 | 2001 |
Actin filament stress fibers in vascular endothelial cells in vivo AJ Wong, TD Pollard, IM Herman Science 219 (4586), 867-869, 1983 | 430 | 1983 |
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts SH Bigner, PA Humphrey, AJ Wong, B Vogelstein, J Mark, HS Friedman, ... Cancer research 50 (24), 8017-8022, 1990 | 407 | 1990 |
Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor M Holgado-Madruga, DK Moscatello, DR Emlet, R Dieterich, AJ Wong Proceedings of the National Academy of Sciences 94 (23), 12419-12424, 1997 | 396 | 1997 |
Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor DK Moscatello, M Holgado-Madruga, DR Emlet, RB Montgomery, ... Journal of Biological Chemistry 273 (1), 200-206, 1998 | 395 | 1998 |
The GLI-Kruppel Family of Human Genes JM Ruppert, KW Kinzler, AJ Wong, SH Bigner, FT Kao, ML Law, ... Molecular and cellular biology 8 (8), 3104-3113, 1988 | 385 | 1988 |
Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas IE Garcia de Palazzo, GP Adams, P Sundareshan, AJ Wong, JR Testa, ... Cancer research 53 (14), 3217-3220, 1993 | 365 | 1993 |
The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor … CR Maroun, MA Naujokas, M Holgado-Madruga, AJ Wong, M Park Molecular and cellular biology 20 (22), 8513-8525, 2000 | 347 | 2000 |
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma M Monje, SS Mitra, ME Freret, TB Raveh, J Kim, M Masek, JL Attema, G Li, ... Proceedings of the National Academy of Sciences 108 (11), 4453-4458, 2011 | 345 | 2011 |
Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts PA Humphrey, AJ Wong, B Vogelstein, HS Friedman, MH Werner, ... Cancer research 48 (8), 2231-2238, 1988 | 341 | 1988 |
Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor. DK Moscatello, M Santra, DM Mann, DJ McQuillan, AJ Wong, RV Iozzo The Journal of clinical investigation 101 (2), 406-412, 1998 | 337 | 1998 |
Gene Amplification of c-myc and N-myc in Small Cell Carcinoma of the Lung AJ Wong, JM Ruppert, J Eggleston, SR Hamilton, SB Baylin, B Vogelstein Science 233 (4762), 461-464, 1986 | 314 | 1986 |
Transformational and altered signal transduction by a naturally occurring mutant EGF receptor. DK Moscatello, RB Montgomery, P Sundareshan, H McDanel, MY Wong, ... Oncogene 13 (1), 85-96, 1996 | 293 | 1996 |