Artificial Metalloenzymes: Reaction Scope and Optimization Strategies F Schwizer, Y Okamoto, T Heinisch, Y Gu, MM Pellizzoni, V Lebrun, ... Chemical reviews 1 (118), 142-231, 2018 | 582 | 2018 |
Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes V Köhler, YM Wilson, M Dürrenberger, D Ghislieri, E Churakova, T Quinto, ... Nature Chemistry 5 (2), 93-99, 2013 | 335 | 2013 |
Cytochromes P450 as useful biocatalysts: addressing the limitations E O'Reilly, V Köhler, SL Flitsch, NJ Turner Chemical Communications 47 (9), 2490-2501, 2011 | 271 | 2011 |
Enantioselective biocatalytic oxidative desymmetrization of substituted pyrrolidines V Köhler, KR Bailey, A Znabet, J Raftery, M Helliwell, NJ Turner Angewandte Chemie 122 (12), 2228-2230, 2010 | 155 | 2010 |
Highly stereoselective synthesis of substituted prolyl peptides using a combination of biocatalytic desymmetrization and multicomponent reactions A Znabet, E Ruijter, FJJ de Kanter, V Köhler, M Helliwell, NJ Turner, ... Angewandte Chemie 122 (31), 5417-5420, 2010 | 138 | 2010 |
Artificial concurrent catalytic processes involving enzymes V Köhler, NJ Turner Chemical Communications 51 (3), 450-464, 2015 | 124 | 2015 |
Chiral Boron‐Bridged Bisoxazolines: Readily Available Anionic Ligands for Asymmetric Catalysis C Mazet, V Köhler, A Pfaltz Angewandte Chemie International Edition 44 (31), 4888-4891, 2005 | 109 | 2005 |
The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution KE Atkin, R Reiss, V Koehler, KR Bailey, S Hart, JP Turkenburg, ... Journal of molecular biology 384 (5), 1218-1231, 2008 | 97 | 2008 |
Efficient In Situ Regeneration of NADH Mimics by an Artificial Metalloenzyme Y Okamoto, V Kohler, CE Paul, F Hollmann, TR Ward ACS Catalysis 6 (6), 3553-3557, 2016 | 96 | 2016 |
Improving the catalytic performance of an artificial metalloenzyme by computational design T Heinisch, M Pellizzoni, M Dürrenberger, CE Tinberg, V Köhler, ... Journal of the American Chemical Society 137 (32), 10414-10419, 2015 | 93 | 2015 |
Kinetic resolution of diols and pyridyl alcohols by Cu (II)(borabox)-catalyzed acylation C Mazet, S Roseblade, V Köhler, A Pfaltz Organic letters 8 (9), 1879-1882, 2006 | 93 | 2006 |
Recent trends in biomimetic NADH regeneration T Quinto, V Köhler, TR Ward Topics in catalysis 57, 321-331, 2014 | 85 | 2014 |
OsO4⋅Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis‐Dihydroxylation of Olefins V Köhler, J Mao, T Heinisch, A Pordea, A Sardo, YM Wilson, L Knörr, ... Angewandte Chemie 123 (46), 11055-11058, 2011 | 84 | 2011 |
An NAD (P) H-dependent artificial transfer hydrogenase for multienzymatic cascades Y Okamoto, V Kohler, TR Ward Journal of the American Chemical Society 138 (18), 5781-5784, 2016 | 83 | 2016 |
Genetic optimization of the catalytic efficiency of artificial imine reductases based on biotin–streptavidin technology F Schwizer, V Köhler, M Dürrenberger, L Knörr, TR Ward ACS Catalysis 3 (8), 1752-1755, 2013 | 59 | 2013 |
Protein-based hybrid catalysts—design and evolution V Köhler, YM Wilson, C Lo, A Sardo, TR Ward Current opinion in biotechnology 21 (6), 744-752, 2010 | 51 | 2010 |
Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope A Robin, V Köhler, A Jones, A Ali, PP Kelly, E O'Reilly, NJ Turner, ... Beilstein journal of organic chemistry 7 (1), 1494-1498, 2011 | 46 | 2011 |
Expanding the chemical diversity in artificial imine reductases based on the biotin–streptavidin technology T Quinto, F Schwizer, JM Zimbron, A Morina, V Köhler, TR Ward ChemCatChem 6 (4), 1010-1014, 2014 | 38 | 2014 |
First domino mukaiyama-aldol cyclizations of 1, 3-Bis (trimethylsiloxy)-1, 3-butadienes with 1, 2-diketones P Langer, V Koehler Organic Letters 2 (11), 1597-1599, 2000 | 37 | 2000 |
ery, M. Helliwell and NJ Turner V Köhler, KR Bailey, A Znabet, J Ra Angew. Chem., Int. Ed 49, 2182-2184, 2010 | 29 | 2010 |