The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation Z Li, J Guo, Y Wu, Q Zhou Nucleic acids research 41 (1), 277-287, 2013 | 340 | 2013 |
LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection PJ Vorster, J Guo, A Yoder, W Wang, Y Zheng, X Xu, D Yu, M Spear, Y Wu Journal of Biological Chemistry 286 (14), 12554-12564, 2011 | 115 | 2011 |
Spinoculation triggers dynamic actin and cofilin activity that facilitates HIV-1 infection of transformed and resting CD4 T cells J Guo, W Wang, D Yu, Y Wu Journal of virology 85 (19), 9824-9833, 2011 | 106 | 2011 |
Single-particle tracking of human immunodeficiency virus type 1 productive entry into human primary macrophages Q Li, W Li, W Yin, J Guo, ZP Zhang, D Zeng, X Zhang, Y Wu, XE Zhang, ... ACS nano 11 (4), 3890-3903, 2017 | 88 | 2017 |
The trinity of the cortical actin in the initiation of HIV-1 infection M Spear, J Guo, Y Wu Retrovirology 9, 1-13, 2012 | 61 | 2012 |
Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors Y Yin, K Zheng, N Eid, S Howard, JH Jeong, F Yi, J Guo, CM Park, ... Journal of medicinal chemistry 58 (4), 1846-1861, 2015 | 57 | 2015 |
Effects of microtubule modulators on HIV-1 infection of transformed and resting CD4 T cells A Yoder, J Guo, D Yu, Z Cui, XE Zhang, Y Wu Journal of virology 85 (6), 3020-3024, 2011 | 47 | 2011 |
A dichotomy in cortical actin and chemotactic actin activity between human memory and naive T cells contributes to their differential susceptibility to HIV-1 infection W Wang, J Guo, D Yu, PJ Vorster, WJ Chen, Y Wu Journal of Biological Chemistry 287 (42), 35455-35469, 2012 | 42 | 2012 |
Discovery of novel small-molecule inhibitors of LIM domain kinase for inhibiting HIV-1 F Yi, J Guo, D Dabbagh, M Spear, S He, K Kehn-Hall, J Fontenot, Y Yin, ... Journal of virology 91 (13), 10.1128/jvi. 02418-16, 2017 | 41 | 2017 |
HIV-1 triggers WAVE2 phosphorylation in primary CD4 T cells and macrophages, mediating Arp2/3-dependent nuclear migration M Spear, J Guo, A Turner, D Yu, W Wang, B Meltzer, S He, X Hu, H Shang, ... Journal of Biological Chemistry 289 (10), 6949-6959, 2014 | 40 | 2014 |
Therapeutic doses of irradiation activate viral transcription and induce apoptosis in HIV-1 infected cells S Iordanskiy, R Van Duyne, GC Sampey, CM Woodson, K Fry, ... Virology 485, 1-15, 2015 | 35 | 2015 |
Genistein interferes with SDF-1-and HIV-mediated actin dynamics and inhibits HIV infection of resting CD4 T cells J Guo, X Xu, TK Rasheed, A Yoder, D Yu, H Liang, F Yi, T Hawley, T Jin, ... Retrovirology 10, 1-15, 2013 | 35 | 2013 |
Novel anti‐HIV therapeutics targeting chemokine receptors and actin regulatory pathways M Spear, J Guo, Y Wu Immunological reviews 256 (1), 300-312, 2013 | 26 | 2013 |
Tat controls transcriptional persistence of unintegrated HIV genome in primary human macrophages B Meltzer, D Dabbagh, J Guo, F Kashanchi, M Tyagi, Y Wu Virology 518, 241-252, 2018 | 24 | 2018 |
Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody S He, Y Fu, J Guo, M Spear, J Yang, B Trinité, C Qin, S Fu, Y Jiang, ... Science Advances 5 (1), eaat7911, 2019 | 17 | 2019 |
Involvement of LIM kinase 1 in actin polarization in human CD4 T cells X Xu, J Guo, PJ Vorster, Y Wu Communicative & integrative biology 5 (4), 381-383, 2012 | 17 | 2012 |
BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection I Guendel, BW Meltzer, A Baer, SM Dever, K Valerie, J Guo, Y Wu, ... Virology journal 12, 1-14, 2015 | 15 | 2015 |
Inhibition of HIV replication in vitro by clinical immunosuppressants and chemotherapeutic agents T Hawley, M Spear, J Guo, Y Wu Cell & Bioscience 3, 1-6, 2013 | 15 | 2013 |
Studies using IPS cells support a possible link between ZIKA and microcephaly J Guo Cell & Bioscience 6, 1-2, 2016 | 10 | 2016 |
Genistein and HIV infection J Guo, Y Wu HIV/AIDS, 125-134, 2018 | 6 | 2018 |