Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle J Walklate, K Kao, M Regnier, MA Geeves Journal of Biological Chemistry 298 (3), 2022 | 33 | 2022 |
The biochemically defined super relaxed state of myosin—a paradox S Mohran, K Kooiker, M Mahoney-Schaefer, C Mandrycky, K Kao, AY Tu, ... Journal of Biological Chemistry 300 (1), 2024 | 4 | 2024 |
Sorbents for treatment of hereditary hemochromatosis A Wilson, L Laguna, L Yew, K Kao, K Bauguess, J Wang, S de la O, ... Medicinal Chemistry Research 31, 85-93, 2022 | 2 | 2022 |
Measuring the Contractile Kinetics of Isolated Myofibrils from Human-Induced Pluripotent Stem Cell Derived Cardiomyocyte (hiPSC-CM) Models of Cardiomyopathy S Mohran, S Steczina, C Mandrycky, K Kao, M Regnier Familial Cardiomyopathies: Methods and Protocols, 213-233, 2023 | 1 | 2023 |
Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration S Lee, ASV Roest, CA Blair, K Kao, SB Bremner, MC Childers, D Pathak, ... bioRxiv, 2023.06. 08.544276, 2023 | 1 | 2023 |
Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration S Lee, AS Vander Roest, CA Blair, K Kao, SB Bremner, MC Childers, ... Proceedings of the National Academy of Sciences 121 (19), e2318413121, 2024 | | 2024 |
Mechanisms of myosin, myofibril, and cardiomyocyte dysfunction with the MYH7 R403Q mutation in porcine ventricle muscle S Mohran, S Steczina, KB Kooiker, T McMillen, C Mandrycky, MC Childers, ... Biophysical Journal 123 (3), 267a, 2024 | | 2024 |
A molecular-scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation KY Kao, MC Childers, S Mohran, M Regnier Biophysical Journal 123 (3), 267a, 2024 | | 2024 |
A molecular dynamics investigation of the dysfunction of the dilated cardiomyopathy-associated MYH7 mutation R369Q AM Prabhala, MC Childers, KY Kao, M Regnier Biophysical Journal 123 (3), 267a, 2024 | | 2024 |
Molecular dynamics models demonstrate alterations in troponin’s function caused by cardiomyopathy-associated mutations S Malingen, MC Childers, T Tune, KY Kao, TL Daniel, F Moussavi-Harami, ... Biophysical Journal 123 (3), 401a-402a, 2024 | | 2024 |
Protocols for Myosin and Actin-Myosin Assays Using Rapid, Stopped-Flow Kinetics K Kao, MA Geeves Familial Cardiomyopathies: Methods and Protocols, 191-211, 2023 | | 2023 |
The β-myosin G256E mutation impairs relaxation by altering transducer stiffness MC Childers, KY Kao, S Mohran, M Regnier Biophysical Journal 122 (3), 402a, 2023 | | 2023 |
Elucidating the mechanism of Danicamtiv on force, kinetics, and myosin structure and function KB Kooiker, S Mohran, W Ma, GV Flint, KY Kao, L Qi, T McMillen, S Neys, ... Biophysical Journal 122 (3), 453a, 2023 | | 2023 |
A molecular scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation KY Kao, MC Childers, S Mohran, MA Geeves, M Regnier Biophysical Journal 122 (3), 402a, 2023 | | 2023 |
Mutation to Troponin Inhibitor3 Switch Domain Causes Restrictive Cardiomyopathy by Reducing Sensitivity to Beta-Adrenergic Stimulus JM Duran, M Manso, P Bushway, K Kao, TM Wang, S Maisel, Y Gu, ... Circulation 146 (Suppl_1), A14960-A14960, 2022 | | 2022 |
Mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation studied using CRISPR-edited hiPSC-CMs KY Kao, MC Childers, S Mohran, M Regnier Biophysical Journal 121 (3), 109a, 2022 | | 2022 |
Disease in a Dish Crispr-Edited HIPSC-CMS to Study the Cellular and Subcellular Mechanisms of HCM KY Kao, MC Childers, S Mohran, A Asencio, M Regnier Biophysical Journal 120 (3), 254a, 2021 | | 2021 |
Investigation of Advanced Adsorbents for Removal of Excess Iron from the Body A Wilson, K Kao, L Laguna, K Bauguess, G Romme, WJR Gilbert, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
A Human Variant in the the Troponin Inhibitor3 Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model JM Duran, K Kao, E Silver, S Maisel, A Shathaya, AM Manso, Y Gu, ... | | |