Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ... Nature genetics 36 (6), 585-595, 2004 | 2819 | 2004 |
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy B Ravikumar, R Duden, DC Rubinsztein Human molecular genetics 11 (9), 1107-1117, 2002 | 1352 | 2002 |
Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum F Letourneur, EC Gaynor, S Hennecke, C Demolliere, R Duden, SD Emr, ... Cell 79 (7), 1199-1207, 1994 | 1008 | 1994 |
β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to β-adaptin R Duden, G Griffiths, R Frank, P Argos, TE Kreis Cell 64 (3), 649-665, 1991 | 595 | 1991 |
The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra-Golgi trafficking, interacts with Golgi SNAREs and COPI vesicle coat proteins ES Suvorova, R Duden, VV Lupashin The Journal of cell biology 157 (4), 631-643, 2002 | 271 | 2002 |
ER-to-Golgi transport: Cop I and Cop II function R Duden Molecular membrane biology 20 (3), 197-207, 2003 | 250 | 2003 |
KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET I Majoul, M Straub, SW Hell, R Duden, HD Soeling Developmental cell 1 (1), 139-153, 2001 | 245 | 2001 |
Beta-COP localizes mainly to the cis-Golgi side in exocrine pancreas. A Oprins, R Duden, TE Kreis, HJ Geuze, JW Slot The Journal of cell biology 121 (1), 49-59, 1993 | 234 | 1993 |
COP I domains required for coatomer integrity, and novel interactions with ARF and ARF‐GAP A Eugster, G Frigerio, M Dale, R Duden The EMBO journal, 2000 | 233 | 2000 |
Drebrin is a novel connexin-43 binding partner that links gap junctions to the submembrane cytoskeleton E Butkevich, S Hülsmann, D Wenzel, T Shirao, R Duden, I Majoul Current biology 14 (8), 650-658, 2004 | 231 | 2004 |
Yeast beta-and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic. R Duden, M Hosobuchi, S Hamamoto, M Winey, B Byers, R Schekman Journal of Biological Chemistry 269 (39), 24486-24495, 1994 | 181 | 1994 |
Delta‐and zeta‐COP, two coatomer subunits homologous to clathrin‐associated proteins, are involved in ER retrieval. P Cosson, C Demolliere, S Hennecke, R Duden, F Letourneur The EMBO journal 15 (8), 1792-1798, 1996 | 180 | 1996 |
ARF-GAP–mediated interaction between the ER-Golgi v-SNAREs and the COPI coat U Rein, U Andag, R Duden, HD Schmitt, A Spang The Journal of cell biology 157 (3), 395-404, 2002 | 170 | 2002 |
γ‐COP appendage domain–structure and function PJ Watson, G Frigerio, BM Collins, R Duden, DJ Owen Traffic 5 (2), 79-88, 2004 | 160 | 2004 |
New Mutants of Saccharomyces cerevisiae Affected in the Transport of Proteins From the Endoplasmic Reticulum to the Golgi Complex LJ Wuestehube, R Duden, A Eun, S Hamamoto, P Korn, R Ram, ... Genetics 142 (2), 393-406, 1996 | 160 | 1996 |
Organization of desmosomal plaque proteins in cells growing at low calcium concentrations. R Duden, WW Franke The Journal of cell biology 107 (3), 1049-1063, 1988 | 158 | 1988 |
Molecular basis for recognition of dilysine trafficking motifs by COPI LP Jackson, M Lewis, HM Kent, MA Edeling, PR Evans, R Duden, ... Developmental cell 23 (6), 1255-1262, 2012 | 149 | 2012 |
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae S Springer, E Chen, R Duden, M Marzioch, A Rowley, S Hamamoto, ... Proceedings of the National Academy of Sciences 97 (8), 4034-4039, 2000 | 149 | 2000 |
The α-and β′-COP WD40 domains mediate cargo-selective interactions with distinct di-lysine motifs A Eugster, G Frigerio, M Dale, R Duden Molecular biology of the cell 15 (3), 1011-1023, 2004 | 142 | 2004 |
Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy B Ravikumar, A Stewart, H Kita, K Kato, R Duden, DC Rubinsztein Human molecular genetics 12 (9), 985-994, 2003 | 142 | 2003 |