TSLP produced by keratinocytes promotes allergen sensitization through skin and thereby triggers atopic march in mice JM Leyva-Castillo, P Hener, H Jiang, M Li Journal of Investigative Dermatology 133 (1), 154-163, 2013 | 247 | 2013 |
IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells C Galand, JM Leyva-Castillo, J Yoon, A Han, MS Lee, ANJ McKenzie, ... Journal of Allergy and Clinical Immunology 138 (5), 1356-1366, 2016 | 218 | 2016 |
Mechanical skin injury promotes food anaphylaxis by driving intestinal mast cell expansion JM Leyva-Castillo, C Galand, C Kam, O Burton, M Gurish, MA Musser, ... Immunity 50 (5), 1262-1275. e4, 2019 | 195 | 2019 |
Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade JM Leyva-Castillo, P Hener, P Michea, H Karasuyama, S Chan, ... Nature communications 4 (1), 2847, 2013 | 168 | 2013 |
RORα-expressing T regulatory cells restrain allergic skin inflammation N Malhotra, JM Leyva-Castillo, U Jadhav, O Barreiro, C Kam, NK O’Neill, ... Science immunology 3 (21), eaao6923, 2018 | 112 | 2018 |
Human RELA haploinsufficiency results in autosomal-dominant chronic mucocutaneous ulceration YR Badran, F Dedeoglu, JM Leyva Castillo, W Bainter, TK Ohsumi, ... Journal of Experimental Medicine 214 (7), 1937-1947, 2017 | 95 | 2017 |
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization J Yoon, JM Leyva-Castillo, G Wang, C Galand, MK Oyoshi, L Kumar, ... Journal of Experimental Medicine 213 (10), 2147-2166, 2016 | 94 | 2016 |
ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation JM Leyva-Castillo, C Galand, S Mashiko, R Bissonnette, A McGurk, ... Journal of Allergy and Clinical Immunology 145 (6), 1606-1614. e4, 2020 | 87 | 2020 |
A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma H Harb, E Stephen-Victor, E Crestani, M Benamar, A Massoud, Y Cui, ... Nature immunology 21 (11), 1359-1370, 2020 | 86 | 2020 |
IL-22 derived from γδ T cells restricts Staphylococcus aureus infection of mechanically injured skin N Malhotra, J Yoon, JM Leyva-Castillo, C Galand, N Archer, LS Miller, ... Journal of Allergy and Clinical Immunology 138 (4), 1098-1107. e3, 2016 | 63 | 2016 |
Mast cell–derived IL-13 downregulates IL-12 production by skin dendritic cells to inhibit the TH1 cell response to cutaneous antigen exposure JM Leyva-Castillo, M Das, E Artru, J Yoon, C Galand, RS Geha Journal of Allergy and Clinical Immunology 147 (6), 2305-2315. e3, 2021 | 49 | 2021 |
IL-22 promotes allergic airway inflammation in epicutaneously sensitized mice JM Leyva-Castillo, J Yoon, RS Geha Journal of Allergy and Clinical Immunology 143 (2), 619-630. e7, 2019 | 49 | 2019 |
S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis L Deng, F Costa, KJ Blake, S Choi, A Chandrabalan, MS Yousuf, S Shiers, ... Cell 186 (24), 5375-5393. e25, 2023 | 34 | 2023 |
Counterregulation between thymic stromal lymphopoietin–and IL-23–driven immune axes shapes skin inflammation in mice with epidermal barrier defects J Li, JM Leyva-Castillo, P Hener, A Eisenmann, S Zaafouri, N Jonca, ... Journal of Allergy and Clinical Immunology 138 (1), 150-161. e13, 2016 | 28 | 2016 |
Single-cell transcriptome profile of mouse skin undergoing antigen-driven allergic inflammation recapitulates findings in atopic dermatitis skin lesions JM Leyva-Castillo, L Sun, SY Wu, S Rockowitz, P Sliz, RS Geha Journal of Allergy and Clinical Immunology 150 (2), 373-384, 2022 | 26 | 2022 |
Linker-Improved Chimeric Endolysin Selectively Kills Staphylococcus aureus In Vitro, on Reconstituted Human Epidermis, and in a Murine Model of Skin Infection F Eichenseher, BL Herpers, P Badoux, JM Leyva-Castillo, RS Geha, ... Antimicrobial Agents and Chemotherapy 66 (5), e02273-21, 2022 | 24 | 2022 |
Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection JM Leyva-Castillo, M Das, J Kane, M Strakosha, S Singh, DSH Wong, ... JCI insight 6 (21), 2021 | 21 | 2021 |
Allergic skin inflammation and S. aureus skin colonization are mutually reinforcing JM Leyva-Castillo, A McGurk, MDR Geha Clinical Immunology 218, 108511, 2020 | 20 | 2020 |
Thymic stromal lymphopoietin and atopic diseases JM Leyva-Castillo, M Li Revue Française d'Allergologie 54 (5), 364-376, 2014 | 13 | 2014 |
The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice B Yang, H Wilkie, M Das, M Timilshina, W Bainter, B Woods, M Daya, ... Journal of Allergy and Clinical Immunology 151 (5), 1296-1306. e7, 2023 | 11 | 2023 |