| Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination F Gong, LY Chiu, B Cox, F Aymard, T Clouaire, JW Leung, M Cammarata, ... Genes & development 29 (2), 197-211, 2015 | 246 | 2015 |
| Engineered proteins detect spontaneous DNA breakage in human and bacterial cells C Shee, BD Cox, F Gu, EM Luengas, MC Joshi, LY Chiu, D Magnan, ... Elife 2, e01222, 2013 | 136 | 2013 |
| Acetylation reader proteins: linking acetylation signaling to genome maintenance and cancer F Gong, LY Chiu, KM Miller PLoS genetics 12 (9), e1006272, 2016 | 118 | 2016 |
| Bacteria-to-human protein networks reveal origins of endogenous DNA damage J Xia, LY Chiu, RB Nehring, MAB Núñez, Q Mei, M Perez, Y Zhai, ... Cell 176 (1), 127-143. e24, 2019 | 84 | 2019 |
| ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair JWC Leung, N Makharashvili, P Agarwal, LY Chiu, R Pourpre, ... Genes & development 31 (3), 260-274, 2017 | 82 | 2017 |
| Bromodomain proteins: repairing DNA damage within chromatin LY Chiu, F Gong, KM Miller Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 49 | 2017 |
| Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers LY Chiu, PS Kishnani, TP Chuang, CY Tang, CY Liu, D Bali, D Koeberl, ... Journal of gastroenterology 49, 1274-1284, 2014 | 46 | 2014 |
| A new class of selective ATM inhibitors as combination partners of DNA double-strand break inducing cancer therapies A Zimmermann, FT Zenke, LY Chiu, H Dahmen, U Pehl, T Fuchss, ... Molecular cancer therapeutics 21 (6), 859-870, 2022 | 22 | 2022 |
| DNA-PK inhibitor, M3814, as a new combination partner of mylotarg in the treatment of acute myeloid leukemia MI Carr, A Zimmermann, LY Chiu, FT Zenke, A Blaukat, LT Vassilev Frontiers in oncology 10, 127, 2020 | 22 | 2020 |
| DNA-PK inhibitor peposertib amplifies radiation-induced inflammatory micronucleation and enhances TGFβ/PD-L1 targeted cancer immunotherapy MI Carr, LY Chiu, Y Guo, C Xu, AS Lazorchak, H Yu, G Qin, J Qi, B Marelli, ... Molecular Cancer Research 20 (4), 568-582, 2022 | 21 | 2022 |
| Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses Y Lan, TL Yeung, H Huang, AA Wegener, S Saha, M Toister-Achituv, ... Journal for Immunotherapy of Cancer 10 (7), 2022 | 11 | 2022 |
| M3814, as a New Combination Partner of Mylotarg in the Treatment of Acute Myeloid Leukemia. Front MI Carr, A Zimmermann, LY Chiu, FT Zenke, A Blaukat, LT Vassilev, ... Oncol 10 (127), 10.3389, 2020 | 9 | 2020 |
| Selective ATM inhibition augments radiation-induced inflammatory signaling and cancer cell death LY Chiu, Q Sun, FT Zenke, A Blaukat, LT Vassilev Aging (Albany NY) 15 (2), 492, 2023 | 8 | 2023 |
| Selective inhibition of ATM-dependent double-strand break repair and checkpoint control synergistically enhances the efficacy of ATR inhibitors A Turchick, A Zimmermann, LY Chiu, H Dahmen, B Elenbaas, FT Zenke, ... Molecular Cancer Therapeutics 22 (7), 859-872, 2023 | 3 | 2023 |
| Effect of extended treatment with IAP inhibitor xevinapant post radiotherapy (RT) on efficacy and the tumor microenvironment (TME) in preclinical models. TL Yeung, F Jiang, J Qi, H Yu, LY Chiu, B Marelli, H Wang, ... Journal of Clinical Oncology 41 (16_suppl), 6027-6027, 2023 | 3 | 2023 |
| Extended treatment with IAP inhibitor xevinapant post radiotherapy improves therapeutic efficacy and promotes antitumor immunity in preclinical models TL Yeung, F Jiang, H Huang, H Yu, LY Chiu, M Bonnemaison, B Marelli, ... Cancer Research 84 (6_Supplement), 2921-2921, 2024 | | 2024 |
| Inhibition of ATM-dependent checkpoint control and DNA double-strand break repair enhances the efficacy of ATR inhibitors A Turchick, A Zimmermann, LY Chiu, H Dahmen, B Elenbaas, FT Zenke, ... Cancer Research 83 (7_Supplement), 6212-6212, 2023 | | 2023 |
| Identification and regulation of DNA damage response pathways in human cancer cells LY Chiu | | 2018 |
