| Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells S Hitoshi, T Alexson, V Tropepe, D Donoviel, AJ Elia, JS Nye, RA Conlon, ... Genes & development 16 (7), 846-858, 2002 | 846 | 2002 |
| Mice lacking both presenilin genes exhibitearlyembryonic patterningdefects DB Donoviel, AK Hadjantonakis, M Ikeda, H Zheng, PSG Hyslop, ... Genes & development 13 (21), 2801-2810, 1999 | 589 | 1999 |
| Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN DB Donoviel, DD Freed, H Vogel, DG Potter, E Hawkins, JP Barrish, ... Molecular and cellular biology, 2001 | 559 | 2001 |
| Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1 Z Zhang, P Nadeau, W Song, D Donoviel, M Yuan, A Bernstein, ... Nature cell biology 2 (7), 463-465, 2000 | 529 | 2000 |
| mdmx is a negative regulator of p53 activity in vivo RA Finch, DB Donoviel, D Potter, M Shi, A Fan, DD Freed, C Wang, ... Cancer research 62 (11), 3221-3225, 2002 | 262 | 2002 |
| Presenilin-1 and presenilin-2 exhibit distinct yet overlapping γ-secretase activities MT Lai, E Chen, MC Crouthamel, J DiMuzio-Mower, M Xu, Q Huang, ... Journal of Biological Chemistry 278 (25), 22475-22481, 2003 | 212 | 2003 |
| Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice A Shiels, S Bassnett, K Varadaraj, R Mathias, K Al-Ghoul, J Kuszak, ... Physiological genomics 7 (2), 179-186, 2001 | 161 | 2001 |
| Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression N Sato, F Urano, J Yoon Leem, SH Kim, M Li, D Donoviel, A Bernstein, ... Nature cell biology 2 (12), 863-870, 2000 | 158 | 2000 |
| Analysis of muscle creatine kinase gene regulatory elements in skeletal and cardiac muscles of transgenic mice D B. Donoviel, M A. Shield, J N. Buskin, H S. Haugen, C H. Clegg, ... Molecular and cellular biology 16 (4), 1649-1658, 1996 | 125 | 1996 |
| Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice G Donoho, MA Brenneman, TX Cui, D Donoviel, H Vogel, EH Goodwin, ... Genes, Chromosomes and Cancer 36 (4), 317-331, 2003 | 117 | 2003 |
| The impact of sex and gender on adaptation to space: executive summary S Mark, GBI Scott, DB Donoviel, LB Leveton, E Mahoney, JB Charles, ... Journal of women's health 23 (11), 941-947, 2014 | 99 | 2014 |
| Notch receptor cleavage depends on but is not directly executed by presenilins Y Taniguchi, H Karlström, J Lundkvist, T Mizutani, A Otaka, M Vestling, ... Proceedings of the National Academy of Sciences 99 (6), 4014-4019, 2002 | 79 | 2002 |
| Identification and characterization of presenilin-independent Notch signaling BE Berechid, M Kitzmann, DR Foltz, AH Roach, D Seiffert, LA Thompson, ... Journal of Biological Chemistry 277 (10), 8154-8165, 2002 | 70 | 2002 |
| High‐throughput screening of mouse knockout lines identifies true lean and obese phenotypes R Brommage, U Desai, JP Revelli, DB Donoviel, GK Fontenot, ... Obesity 16 (10), 2362-2367, 2008 | 64 | 2008 |
| Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: induction by basic fibroblast growth factor DB Donoviel, SL Amacher, KW Judge, P Bornstein Journal of cellular physiology 145 (1), 16-23, 1990 | 59 | 1990 |
| Structural analysis and expression of the human thrombospondin gene promoter. DB Donoviel, P Framson, CF Eldridge, M Cooke, S Kobayashi, ... Journal of Biological Chemistry 263 (35), 18590-18593, 1988 | 58 | 1988 |
| Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene DB Donoviel, MS Donoviel, E Fan, AK Hadjantonakis, A Bernstein Mechanisms of development 78 (1-2), 203-207, 1998 | 57 | 1998 |
| Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling T Takeda, M Asahi, O Yamaguchi, S Hikoso, H Nakayama, Y Kusakari, ... The FASEB journal 19 (14), 2069-2071, 2005 | 56 | 2005 |
| Functional characterization of novel presenilin-2 variants identified in human breast cancers MD To, N Gokgoz, TG Doyle, DB Donoviel, JA Knight, PS Hyslop, ... Oncogene 25 (25), 3557-3564, 2006 | 50 | 2006 |
| Novel indications for commonly used medications as radiation protectants in spaceflight MF McLaughlin, DB Donoviel, JA Jones Aerospace medicine and human performance 88 (7), 665-676, 2017 | 38 | 2017 |
