| Structure of arylamine N-acetyltransferase reveals a catalytic triad JC Sinclair, J Sandy, R Delgoda, E Sim, MEM Noble Nature structural biology 7 (7), 560-564, 2000 | 257 | 2000 |
| The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis—an enzyme which inactivates the anti-tubercular drug, isoniazid J Sandy, A Mushtaq, A Kawamura, J Sinclair, E Sim, M Noble Journal of molecular biology 318 (4), 1071-1083, 2002 | 127 | 2002 |
| Arylamine N-acetyltransferases–of mice, men and microorganisms A Upton, N Johnson, J Sandy, E Sim Trends in pharmacological sciences 22 (3), 140-146, 2001 | 124 | 2001 |
| Arylamine N‐acetyltransferase of Mycobacterium tuberculosis is a polymorphic enzyme and a site of isoniazid metabolism AM Upton, A Mushtaq, TC Victor, SL Sampson, J Sandy, DM Smith, ... Molecular microbiology 42 (2), 309-317, 2001 | 112 | 2001 |
| Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions JE Harmer, MJ Hiscox, PC Dinis, SJ Fox, A Iliopoulos, JE Hussey, ... Biochemical Journal 464 (1), 123-133, 2014 | 82 | 2014 |
| Binding of the anti‐tubercular drug isoniazid to the arylamine N‐acetyltransferase protein from Mycobacterium smegmatis J Sandy, S Holton, E Fullam, E Sim, M Noble Protein Science 14 (3), 775-782, 2005 | 78 | 2005 |
| Arylamine N-acetyltransferases: a pharmacogenomic approach to drug metabolism and endogenous function E Sim, K Pinter, A Mushtaq, A Upton, J Sandy, S Bhakta, M Noble Biochemical Society Transactions 31 (3), 615-619, 2003 | 76 | 2003 |
| Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines J Sandy, A Mushtaq, SJ Holton, P Schartau, MEM Noble, E Sim Biochemical Journal 390 (1), 115-123, 2005 | 70 | 2005 |
| Arylamine N-acetyltransferases in mycobacteria E Sim, J Sandy, D Evangelopoulos, E Fullam, S Bhakta, I Westwood, ... Current Drug Metabolism 9 (6), 510-519, 2008 | 52 | 2008 |
| Structure of Mesorhizobium loti arylamine N-acetyltransferase 1 SJ Holton, J Dairou, J Sandy, F Rodrigues-Lima, JM Dupret, MEM Noble, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2005 | 50 | 2005 |
| VMXi: a fully automated, fully remote, high-flux in situ macromolecular crystallography beamline J Sanchez-Weatherby, J Sandy, H Mikolajek, CMC Lobley, M Mazzorana, ... Journal of synchrotron radiation 26 (1), 291-301, 2019 | 44 | 2019 |
| Applications of thin-film sandwich crystallization platforms D Axford, P Aller, J Sanchez-Weatherby, J Sandy Acta Crystallographica Section F: Structural Biology Communications 72 (4 …, 2016 | 41 | 2016 |
| xia2. multiplex: a multi-crystal data-analysis pipeline RJ Gildea, J Beilsten-Edmands, D Axford, S Horrell, P Aller, J Sandy, ... Acta Crystallographica Section D: Structural Biology 78 (6), 752-769, 2022 | 34 | 2022 |
| NMR investigation of the catalytic mechanism of arylamine N-acetyltransferase from Salmonella typhimurium R Delgoda, LY Lian, J Sandy, E Sim Biochimica et Biophysica Acta (BBA)-General Subjects 1620 (1-3), 8-14, 2003 | 30 | 2003 |
| Mutational and expression analysis of tbnat and its response to isoniazid C Sholto-Douglas-Vernon, J Sandy, TC Victor, E Sim, PD Helden Journal of medical microbiology 54 (12), 1189-1197, 2005 | 29 | 2005 |
| Application of in situ diffraction in high-throughput structure determination platforms P Aller, J Sanchez-Weatherby, J Foadi, G Winter, CMC Lobley, D Axford, ... Structural Proteomics: High-Throughput Methods, 233-253, 2015 | 23 | 2015 |
| Structural investigation of mutant Mycobacterium smegmatis arylamine N-acetyltransferase: a model for a naturally occurring functional polymorphism in Mycobacterium … A Kawamura, J Sandy, A Upton, M Noble, E Sim Protein expression and purification 27 (1), 75-84, 2003 | 22 | 2003 |
| Crystal structure of the human Tip41 orthologue, TIPRL, reveals a novel fold and a binding site for the PP2Ac C-terminus V Scorsato, TB Lima, GL Righetto, NIT Zanchin, J Brandão-Neto, J Sandy, ... Scientific reports 6 (1), 30813, 2016 | 19 | 2016 |
| A generic protocol for protein crystal dehydration using the HC1b humidity controller CMC Lobley, J Sandy, J Sanchez-Weatherby, M Mazzorana, T Krojer, ... Acta Crystallographica Section D: Structural Biology 72 (5), 629-640, 2016 | 19 | 2016 |
| Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high throughput screening I M Westwood, A Kawamura, A J Russell, J Sandy, S G Davies, E Sim Combinatorial chemistry & high throughput screening 14 (2), 117-124, 2011 | 19 | 2011 |
