Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia LM Hablitz, HS Vinitsky, Q Sun, FF Stæger, B Sigurdsson, KN Mortensen, ... Science advances 5 (2), eaav5447, 2019 | 407 | 2019 |
The glymphatic system: Current understanding and modeling T Bohr, PG Hjorth, SC Holst, S Hrabětová, V Kiviniemi, T Lilius, ... IScience 25 (9), 2022 | 106 | 2022 |
Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs TO Lilius, K Blomqvist, NL Hauglund, G Liu, FF Stæger, S Bærentzen, ... Journal of Controlled Release 304, 29-38, 2019 | 92 | 2019 |
The glymphatic system: implications for drugs for central nervous system diseases TJ Lohela, TO Lilius, M Nedergaard Nature Reviews Drug Discovery 21 (10), 763-779, 2022 | 78 | 2022 |
A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in … YA Sidorova, MM Bespalov, AW Wong, O Kambur, V Jokinen, TO Lilius, ... Frontiers in pharmacology 8, 365, 2017 | 54 | 2017 |
Differential spinal and supraspinal activation of glia in a rat model of morphine tolerance V Jokinen, Y Sidorova, H Viisanen, I Suleymanova, H Tiilikainen, Z Li, ... Neuroscience 375, 10-24, 2018 | 52 | 2018 |
Mapping of CSF transport using high spatiotemporal resolution dynamic contrast‐enhanced MRI in mice: effect of anesthesia EH Stanton, NDÅ Persson, RS Gomolka, T Lilius, B Sigurðsson, H Lee, ... Magnetic Resonance in Medicine 85 (6), 3326-3342, 2021 | 51 | 2021 |
Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat TO Lilius, V Jokinen, MS Neuvonen, M Niemi, EA Kalso, PV Rauhala British Journal of Pharmacology 172 (11), 2799-2813, 2015 | 50 | 2015 |
Simultaneous detection of morphine and codeine in the presence of ascorbic acid and uric acid and in human plasma at nafion single-walled carbon nanotube thin-film electrode N Wester, E Mynttinen, J Etula, T Lilius, E Kalso, EI Kauppinen, T Laurila, ... ACS omega 4 (18), 17726-17734, 2019 | 44 | 2019 |
Simultaneous electrochemical detection of tramadol and O-desmethyltramadol with Nafion-coated tetrahedral amorphous carbon electrode E Mynttinen, N Wester, T Lilius, E Kalso, J Koskinen, T Laurila Electrochimica Acta 295, 347-353, 2019 | 41 | 2019 |
Spared nerve injury causes sexually dimorphic mechanical allodynia and differential gene expression in spinal cords and dorsal root ganglia in rats FHG Ahlström, K Mätlik, H Viisanen, KJ Blomqvist, X Liu, TO Lilius, ... Molecular neurobiology 58, 5396-5419, 2021 | 38 | 2021 |
Electrochemical detection of oxycodone and its main metabolites with Nafion-coated single-walled carbon nanotube electrodes E Mynttinen, N Wester, T Lilius, E Kalso, B Mikladal, I Varjos, S Sainio, ... Analytical Chemistry 92 (12), 8218-8227, 2020 | 38 | 2020 |
A survey of molecular imaging of opioid receptors P Cumming, J Marton, TO Lilius, DE Olberg, A Rominger Molecules 24 (22), 4190, 2019 | 36 | 2019 |
Single-walled carbon nanotube network electrodes for the detection of fentanyl citrate N Wester, E Mynttinen, J Etula, T Lilius, E Kalso, BF Mikladal, Q Zhang, ... ACS Applied Nano Materials 3 (2), 1203-1212, 2020 | 35 | 2020 |
Disposable nafion-coated single-walled carbon nanotube test strip for electrochemical quantitative determination of acetaminophen in a finger-prick whole blood sample N Wester, BF Mikladal, I Varjos, A Peltonen, E Kalso, T Lilius, T Laurila, ... Analytical Chemistry 92 (19), 13017-13024, 2020 | 32 | 2020 |
Modulation of morphine-induced antinociception in acute and chronic opioid treatment by ibudilast TO Lilius, PV Rauhala, O Kambur, EA Kalso The Journal of the American Society of Anesthesiologists 111 (6), 1356-1364, 2009 | 32 | 2009 |
Pregabalin enhances the antinociceptive effect of oxycodone and morphine in thermal models of nociception in the rat without any pharmacokinetic interactions V Jokinen, TO Lilius, J Laitila, M Niemi, PV Rauhala, EA Kalso European journal of pain 20 (2), 297-306, 2016 | 31 | 2016 |
Selective detection of morphine in the presence of paracetamol with anodically pretreated dual layer Ti/tetrahedral amorphous carbon electrodes N Wester, J Etula, T Lilius, S Sainio, T Laurila, J Koskinen Electrochemistry Communications 86, 166-170, 2018 | 29 | 2018 |
Genomewide association study of simvastatin pharmacokinetics AJH Mykkänen, S Taskinen, M Neuvonen, M Paile‐Hyvärinen, ... Clinical Pharmacology & Therapeutics 112 (3), 676-686, 2022 | 28 | 2022 |
Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine: from behaviour to drug availability T Lilius, E Kangas, M Niemi, P Rauhala, E Kalso British journal of anaesthesia 120 (4), 818-826, 2018 | 24 | 2018 |