3D structures of individual mammalian genomes studied by single-cell Hi-C TJ Stevens, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee, M Leeb, ... Nature 544 (7648), 59-64, 2017 | 795 | 2017 |
Chromatin organization is a major influence on regional mutation rates in human cancer cells B Schuster-Böckler, B Lehner nature 488 (7412), 504-507, 2012 | 709 | 2012 |
Synonymous mutations frequently act as driver mutations in human cancers F Supek, B Miñana, J Valcárcel, T Gabaldón, B Lehner Cell 156 (6), 1324-1335, 2014 | 613 | 2014 |
Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways B Lehner, C Crombie, J Tischler, A Fortunato, AG Fraser Nature genetics 38 (8), 896-903, 2006 | 593 | 2006 |
Intergenerational and transgenerational epigenetic inheritance in animals MF Perez, B Lehner Nature cell biology 21 (2), 143-151, 2019 | 463 | 2019 |
The rules and impact of nonsense-mediated mRNA decay in human cancers RGH Lindeboom, F Supek, B Lehner Nature genetics 48 (10), 1112-1118, 2016 | 437 | 2016 |
Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity T Vavouri, JI Semple, R Garcia-Verdugo, B Lehner Cell 138 (1), 198-208, 2009 | 413 | 2009 |
Transgenerational transmission of environmental information in C. elegans A Klosin, E Casas, C Hidalgo-Carcedo, T Vavouri, B Lehner Science 356 (6335), 320-323, 2017 | 404 | 2017 |
Differential DNA mismatch repair underlies mutation rate variation across the human genome F Supek, B Lehner Nature 521 (7550), 81-84, 2015 | 389 | 2015 |
Tissue specificity and the human protein interaction network A Bossi, B Lehner Molecular systems biology 5 (1), 260, 2009 | 379 | 2009 |
In search of antisense G Lavorgna, D Dahary, B Lehner, R Sorek, CM Sanderson, G Casari Trends in biochemical sciences 29 (2), 88-94, 2004 | 377 | 2004 |
Molecular mechanisms of epistasis within and between genes B Lehner Trends in Genetics 27 (8), 323-331, 2011 | 348 | 2011 |
A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans I Lee, B Lehner, C Crombie, W Wong, AG Fraser, EM Marcotte Nature genetics 40 (2), 181-188, 2008 | 347 | 2008 |
Antisense transcripts in the human genome B Lehner, G Williams, RD Campbell, CM Sanderson Trends in Genetics 18 (2), 63-65, 2002 | 302 | 2002 |
A first-draft human protein-interaction map B Lehner, AG Fraser Genome biology 5, 1-9, 2004 | 280 | 2004 |
A concentration-dependent liquid phase separation can cause toxicity upon increased protein expression B Bolognesi, NL Gotor, R Dhar, D Cirillo, M Baldrighi, GG Tartaglia, ... Cell reports 16 (1), 222-231, 2016 | 262 | 2016 |
Selection to minimise noise in living systems and its implications for the evolution of gene expression B Lehner Molecular systems biology 4 (1), 170, 2008 | 261 | 2008 |
Genotype to phenotype: lessons from model organisms for human genetics B Lehner Nature Reviews Genetics 14 (3), 168-178, 2013 | 255 | 2013 |
Predicting mutation outcome from early stochastic variation in genetic interaction partners A Burga, MO Casanueva, B Lehner Nature 480 (7376), 250-253, 2011 | 212 | 2011 |
The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy RGH Lindeboom, M Vermeulen, B Lehner, F Supek Nature genetics 51 (11), 1645-1651, 2019 | 206 | 2019 |