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Hugh Sparks
Hugh Sparks
在 ic.ac.uk 的电子邮件经过验证
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Time-lapse 3-D measurements of a glucose biosensor in multicellular spheroids by light sheet fluorescence microscopy in commercial 96-well plates
V Maioli, G Chennell, H Sparks, T Lana, S Kumar, D Carling, A Sardini, ...
Scientific Reports 6 (1), 37777, 2016
612016
Heterogeneity in tumor chromatin-doxorubicin binding revealed by in vivo fluorescence lifetime imaging confocal endomicroscopy
H Sparks, H Kondo, S Hooper, I Munro, G Kennedy, C Dunsby, P French, ...
Nature communications 9 (1), 2662, 2018
412018
Dual-view oblique plane microscopy (dOPM)
H Sparks, L Dent, C Bakal, A Behrens, G Salbreux, C Dunsby
Biomedical optics express 11 (12), 7204-7220, 2020
322020
A flexible wide‐field FLIM endoscope utilising blue excitation light for label‐free contrast of tissue
H Sparks, S Warren, J Guedes, N Yoshida, TC Charn, N Guerra, T Tatla, ...
Journal of biophotonics 8 (1-2), 168-178, 2015
322015
Characterisation of new gated optical image intensifiers for fluorescence lifetime imaging
H Sparks, F Görlitz, DJ Kelly, SC Warren, PA Kellett, E Garcia, ...
Review of Scientific Instruments 88 (1), 2017
262017
Development a flexible light‐sheet fluorescence microscope for high‐speed 3D imaging of calcium dynamics and 3D imaging of cellular microstructure
H Sparks, L Dvinskikh, JM Firth, AJ Francis, SE Harding, C Paterson, ...
Journal of Biophotonics 13 (6), e201960239, 2020
142020
Adaptive light-sheet fluorescence microscopy with a deformable mirror for video-rate volumetric imaging
W Hong, T Wright, H Sparks, L Dvinskikh, K MacLeod, C Paterson, ...
Applied Physics Letters 121 (19), 2022
72022
Video-rate remote refocusing through continuous oscillation of a membrane deformable mirror
T Wright, H Sparks, C Paterson, C Dunsby
Journal of Physics: Photonics 3 (4), 045004, 2021
72021
High-speed 2D light-sheet fluorescence microscopy enables quantification of spatially varying calcium dynamics in ventricular cardiomyocytes
L Dvinskikh, H Sparks, KT MacLeod, C Dunsby
Frontiers in Physiology 14, 1079727, 2023
42023
Alignment and characterization of remote-refocusing systems
W Hong, H Sparks, C Dunsby
Applied Optics 62 (28), 7431-7440, 2023
32023
Remote-refocusing light-sheet fluorescence microscopy enables 3D imaging of electromechanical coupling of hiPSC-derived and adult cardiomyocytes in co-culture
L Dvinskikh, H Sparks, L Brito, KT MacLeod, SE Harding, C Dunsby
Scientific Reports 13 (1), 3342, 2023
32023
Active mesh and neural network pipeline for cell aggregate segmentation
MB Smith, H Sparks, J Almagro, A Chaigne, A Behrens, C Dunsby, ...
Biophysical journal 122 (9), 1586-1599, 2023
22023
Environmentally dependent and independent control of 3D cell shape
LG Dent, N Curry, H Sparks, V Bousgouni, V Maioli, S Kumar, I Munro, ...
Cell Reports 43 (5), 2024
12024
2D LSFM timelapse of cardiomyocyte calcium dynamics
L Dvinskikh, H Sparks, K MacLeod, C Dunsby
Zenodo, 2023
12023
Environmentally dependent and independent control of cell shape determination by rho gtpase regulators in melanoma
LG Dent, N Curry, H Sparks, V Bousgouni, V Maioli, S Kumar, I Munro, ...
bioRxiv, 2021.10. 11.463377, 2021
12021
Development and biomedical application of fluorescence lifetime imaging endoscopes
H Sparks
Imperial College London, 2015
12015
Imaging of MAP kinase dynamics reveals endocytic regulation of pulsatile signalling and network re-wiring in response to targeted therapy in EGFR-mutant non-small cell lung cancer
AMI Le Marois, S Bailey, S Hooper, S Kumar, H Sparks, Y Alexandrov, ...
bioRxiv, 2024.05. 14.594112, 2024
2024
Dual-view oblique plane microscopy for multi-well plate time-lapse 3D imaging assays in cancer research
H Sparks, L Dent, CDH Ratcliffe, N Gustafsson, N Curry, E Sahai, C Bakal, ...
Novel Techniques in Microscopy, NM3C. 3, 2023
2023
Working at the interface of physics and biology: An early career researcher perspective
C Dilliway, O Dyer, E Mandrou, D Mitchell, G Menon, H Sparks, ...
Iscience 25 (12), 2022
2022
Dual-view oblique plane microscopy
H Sparks, J Almagro, A Behrens, G Salbreux, C Dunsby
Novel Techniques in Microscopy, NM2C. 5, 2021
2021
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