Time-lapse 3-D measurements of a glucose biosensor in multicellular spheroids by light sheet fluorescence microscopy in commercial 96-well plates V Maioli, G Chennell, H Sparks, T Lana, S Kumar, D Carling, A Sardini, ... Scientific Reports 6 (1), 37777, 2016 | 61 | 2016 |
Heterogeneity in tumor chromatin-doxorubicin binding revealed by in vivo fluorescence lifetime imaging confocal endomicroscopy H Sparks, H Kondo, S Hooper, I Munro, G Kennedy, C Dunsby, P French, ... Nature communications 9 (1), 2662, 2018 | 41 | 2018 |
Dual-view oblique plane microscopy (dOPM) H Sparks, L Dent, C Bakal, A Behrens, G Salbreux, C Dunsby Biomedical optics express 11 (12), 7204-7220, 2020 | 32 | 2020 |
A flexible wide‐field FLIM endoscope utilising blue excitation light for label‐free contrast of tissue H Sparks, S Warren, J Guedes, N Yoshida, TC Charn, N Guerra, T Tatla, ... Journal of biophotonics 8 (1-2), 168-178, 2015 | 32 | 2015 |
Characterisation of new gated optical image intensifiers for fluorescence lifetime imaging H Sparks, F Görlitz, DJ Kelly, SC Warren, PA Kellett, E Garcia, ... Review of Scientific Instruments 88 (1), 2017 | 26 | 2017 |
Development a flexible light‐sheet fluorescence microscope for high‐speed 3D imaging of calcium dynamics and 3D imaging of cellular microstructure H Sparks, L Dvinskikh, JM Firth, AJ Francis, SE Harding, C Paterson, ... Journal of Biophotonics 13 (6), e201960239, 2020 | 14 | 2020 |
Adaptive light-sheet fluorescence microscopy with a deformable mirror for video-rate volumetric imaging W Hong, T Wright, H Sparks, L Dvinskikh, K MacLeod, C Paterson, ... Applied Physics Letters 121 (19), 2022 | 7 | 2022 |
Video-rate remote refocusing through continuous oscillation of a membrane deformable mirror T Wright, H Sparks, C Paterson, C Dunsby Journal of Physics: Photonics 3 (4), 045004, 2021 | 7 | 2021 |
High-speed 2D light-sheet fluorescence microscopy enables quantification of spatially varying calcium dynamics in ventricular cardiomyocytes L Dvinskikh, H Sparks, KT MacLeod, C Dunsby Frontiers in Physiology 14, 1079727, 2023 | 4 | 2023 |
Alignment and characterization of remote-refocusing systems W Hong, H Sparks, C Dunsby Applied Optics 62 (28), 7431-7440, 2023 | 3 | 2023 |
Remote-refocusing light-sheet fluorescence microscopy enables 3D imaging of electromechanical coupling of hiPSC-derived and adult cardiomyocytes in co-culture L Dvinskikh, H Sparks, L Brito, KT MacLeod, SE Harding, C Dunsby Scientific Reports 13 (1), 3342, 2023 | 3 | 2023 |
Active mesh and neural network pipeline for cell aggregate segmentation MB Smith, H Sparks, J Almagro, A Chaigne, A Behrens, C Dunsby, ... Biophysical journal 122 (9), 1586-1599, 2023 | 2 | 2023 |
Environmentally dependent and independent control of 3D cell shape LG Dent, N Curry, H Sparks, V Bousgouni, V Maioli, S Kumar, I Munro, ... Cell Reports 43 (5), 2024 | 1 | 2024 |
2D LSFM timelapse of cardiomyocyte calcium dynamics L Dvinskikh, H Sparks, K MacLeod, C Dunsby Zenodo, 2023 | 1 | 2023 |
Environmentally dependent and independent control of cell shape determination by rho gtpase regulators in melanoma LG Dent, N Curry, H Sparks, V Bousgouni, V Maioli, S Kumar, I Munro, ... bioRxiv, 2021.10. 11.463377, 2021 | 1 | 2021 |
Development and biomedical application of fluorescence lifetime imaging endoscopes H Sparks Imperial College London, 2015 | 1 | 2015 |
Imaging of MAP kinase dynamics reveals endocytic regulation of pulsatile signalling and network re-wiring in response to targeted therapy in EGFR-mutant non-small cell lung cancer AMI Le Marois, S Bailey, S Hooper, S Kumar, H Sparks, Y Alexandrov, ... bioRxiv, 2024.05. 14.594112, 2024 | | 2024 |
Dual-view oblique plane microscopy for multi-well plate time-lapse 3D imaging assays in cancer research H Sparks, L Dent, CDH Ratcliffe, N Gustafsson, N Curry, E Sahai, C Bakal, ... Novel Techniques in Microscopy, NM3C. 3, 2023 | | 2023 |
Working at the interface of physics and biology: An early career researcher perspective C Dilliway, O Dyer, E Mandrou, D Mitchell, G Menon, H Sparks, ... Iscience 25 (12), 2022 | | 2022 |
Dual-view oblique plane microscopy H Sparks, J Almagro, A Behrens, G Salbreux, C Dunsby Novel Techniques in Microscopy, NM2C. 5, 2021 | | 2021 |