Identification of human brain tumour initiating cells SK Singh, C Hawkins, ID Clarke, JA Squire, J Bayani, T Hide, ... nature 432 (7015), 396-401, 2004 | 9247 | 2004 |
Identification of a cancer stem cell in human brain tumors SK Singh, ID Clarke, M Terasaki, VE Bonn, C Hawkins, J Squire, PB Dirks Cancer research 63 (18), 5821-5828, 2003 | 6897 | 2003 |
Erlotinib in lung cancer—molecular and clinical predictors of outcome MS Tsao, A Sakurada, JC Cutz, CQ Zhu, S Kamel-Reid, J Squire, ... New England Journal of Medicine 353 (2), 133-144, 2005 | 2308 | 2005 |
Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists … NI Lindeman, PT Cagle, MB Beasley, DA Chitale, S Dacic, G Giaccone, ... Journal of Thoracic Oncology 8 (7), 823-859, 2013 | 1939 | 2013 |
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens SM Pollard, K Yoshikawa, ID Clarke, D Danovi, S Stricker, R Russell, ... Cell stem cell 4 (6), 568-580, 2009 | 1149 | 2009 |
Mutations in SUFU predispose to medulloblastoma MD Taylor, L Liu, C Raffel, C Hui, TG Mainprize, X Zhang, R Agatep, ... Nature genetics 31 (3), 306-310, 2002 | 987 | 2002 |
Role of KRAS and EGFR As Biomarkers of Response to Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21 CQ Zhu, G da Cunha Santos, K Ding, A Sakurada, JC Cutz, N Liu, ... Journal of clinical oncology 26 (26), 4268-4275, 2008 | 869 | 2008 |
Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer D Lechardeur, KJ Sohn, M Haardt, PB Joshi, M Monck, RW Graham, ... Gene therapy 6 (4), 482-497, 1999 | 804 | 1999 |
High-resolution mapping of mammalian genes by in situ hybridization to free chromatin. HH Heng, J Squire, LC Tsui Proceedings of the National Academy of Sciences 89 (20), 9509-9513, 1992 | 694 | 1992 |
Clinical implications of PTEN loss in prostate cancer T Jamaspishvili, DM Berman, AE Ross, HI Scher, AM De Marzo, JA Squire, ... Nature Reviews Urology 15 (4), 222-234, 2018 | 563 | 2018 |
Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome R Weksberg, D Ren Shen, Y Ling Fei, Q Li Song, J Squire Nature genetics 5 (2), 143-150, 1993 | 522 | 1993 |
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions R Tomasini, K Tsuchihara, M Wilhelm, M Fujitani, A Rufini, CC Cheung, ... Genes & development 22 (19), 2677-2691, 2008 | 516 | 2008 |
Genetic origin of mutations predisposing to retinoblastoma WK Cavenee, MF Hansen, M Nordenskjold, E Kock, I Maumenee, ... Science 228 (4698), 501-503, 1985 | 511 | 1985 |
EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer AM Haslehurst, M Koti, M Dharsee, P Nuin, K Evans, J Geraci, T Childs, ... BMC cancer 12, 1-10, 2012 | 451 | 2012 |
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity M Meyer, J Reimand, X Lan, R Head, X Zhu, M Kushida, J Bayani, ... Proceedings of the National Academy of Sciences 112 (3), 851-856, 2015 | 417 | 2015 |
Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith–Wiedemann syndrome R Weksberg, C Shuman, O Caluseriu, AC Smith, YL Fei, J Nishikawa, ... Human Molecular Genetics 11 (11), 1317-1325, 2002 | 390 | 2002 |
Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study E Lalonde, AS Ishkanian, J Sykes, M Fraser, H Ross-Adams, N Erho, ... The lancet oncology 15 (13), 1521-1532, 2014 | 380 | 2014 |
Cause and consequences of genetic and epigenetic alterations in human cancer B Sadikovic, K Al-Romaih, JA Squire, M Zielenska Current genomics 9 (6), 394-408, 2008 | 371 | 2008 |
Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype H Ouyang, L Mou, C Luk, N Liu, J Karaskova, J Squire, MS Tsao The American journal of pathology 157 (5), 1623-1631, 2000 | 367 | 2000 |
FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome M Yoshimoto, IW Cunha, RA Coudry, FP Fonseca, CH Torres, FA Soares, ... British journal of cancer 97 (5), 678-685, 2007 | 363 | 2007 |