| Direct observation of the interconversion of normal and toxic forms of α-synuclein N Cremades, SIA Cohen, E Deas, AY Abramov, AY Chen, A Orte, ... Cell 149 (5), 1048-1059, 2012 | 980 | 2012 |
| Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein CW Bertoncini, YS Jung, CO Fernandez, W Hoyer, C Griesinger, TM Jovin, ... Proceedings of the National Academy of Sciences 102 (5), 1430-1435, 2005 | 929 | 2005 |
| Structural characterization of copper (II) binding to α-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease RM Rasia, CW Bertoncini, D Marsh, W Hoyer, D Cherny, M Zweckstetter, ... Proceedings of the National Academy of Sciences 102 (12), 4294-4299, 2005 | 481 | 2005 |
| Interaction of α-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement A Binolfi, RM Rasia, CW Bertoncini, M Ceolin, M Zweckstetter, ... Journal of the American Chemical Society 128 (30), 9893-9901, 2006 | 429 | 2006 |
| Defining long-range order and local disorder in native α-synuclein using residual dipolar couplings P Bernadó, CW Bertoncini, C Griesinger, M Zweckstetter, M Blackledge Journal of the American Chemical Society 127 (51), 17968-17969, 2005 | 280 | 2005 |
| Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation CW Bertoncini, CO Fernandez, C Griesinger, TM Jovin, M Zweckstetter Journal of Biological Chemistry 280 (35), 30649-30652, 2005 | 257 | 2005 |
| Protein amyloids develop an intrinsic fluorescence signature during aggregation FTS Chan, GSK Schierle, JR Kumita, CW Bertoncini, CM Dobson, ... Analyst 138 (7), 2156-2162, 2013 | 225 | 2013 |
| Site-specific interactions of Cu (II) with α and β-synuclein: Bridging the molecular gap between metal binding and aggregation A Binolfi, GR Lamberto, R Duran, L Quintanar, CW Bertoncini, JM Souza, ... Journal of the American Chemical Society 130 (35), 11801-11812, 2008 | 201 | 2008 |
| In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging GS Kaminski Schierle, S Van De Linde, M Erdelyi, EK Esbjörner, T Klein, ... Journal of the American Chemical Society 133 (33), 12902-12905, 2011 | 178 | 2011 |
| Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged α-synuclein MJ Roberti, CW Bertoncini, R Klement, EA Jares-Erijman, TM Jovin Nature methods 4 (4), 345-351, 2007 | 162 | 2007 |
| Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease G Toth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ... PloS one 9 (2), e87133, 2014 | 161 | 2014 |
| Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses M Yolamanova, C Meier, AK Shaytan, V Vas, CW Bertoncini, F Arnold, ... Nature nanotechnology 8 (2), 130-136, 2013 | 154 | 2013 |
| Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ (1–40) and Aβ (1–42) aggregation EK Esbjörner, F Chan, E Rees, M Erdelyi, LM Luheshi, CW Bertoncini, ... Chemistry & biology 21 (6), 732-742, 2014 | 145 | 2014 |
| Structural characterization of the intrinsically unfolded protein β-synuclein, a natural negative regulator of α-synuclein aggregation CW Bertoncini, RM Rasia, GR Lamberto, A Binolfi, M Zweckstetter, ... Journal of molecular biology 372 (3), 708-722, 2007 | 140 | 2007 |
| Bioinorganic chemistry of copper coordination to alpha-synuclein: Relevance to Parkinson's disease A Binolfi, L Quintanar, CW Bertoncini, C Griesinger, CO Fernández Coordination Chemistry Reviews 256 (19-20), 2188-2201, 2012 | 137 | 2012 |
| EPI-001, a compound active against castration-resistant prostate cancer, targets transactivation unit 5 of the androgen receptor E De Mol, RB Fenwick, CTW Phang, V Buzon, E Szulc, A De La Fuente, ... ACS chemical biology 11 (9), 2499-2505, 2016 | 135 | 2016 |
| Chaperone proteostasis in Parkinson's disease: Stabilization of the Hsp70/α‐synuclein complex by Hip C Roodveldt, CW Bertoncini, A Andersson, AT Van Der Goot, ST Hsu, ... The EMBO journal 28 (23), 3758-3770, 2009 | 133 | 2009 |
| A FRET sensor for non‐invasive imaging of amyloid formation in vivo GS Kaminski Schierle, CW Bertoncini, FTS Chan, AT Van Der Goot, ... ChemPhysChem 12 (3), 673-680, 2011 | 127 | 2011 |
| Structural and mechanistic basis behind the inhibitory interaction of PcTS on α-synuclein amyloid fibril formation GR Lamberto, A Binolfi, ML Orcellet, CW Bertoncini, M Zweckstetter, ... Proceedings of the National Academy of Sciences 106 (50), 21057-21062, 2009 | 127 | 2009 |
| On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with Congo red and lacmoid C Lendel, CW Bertoncini, N Cremades, CA Waudby, M Vendruscolo, ... Biochemistry 48 (35), 8322-8334, 2009 | 125 | 2009 |
