ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments A Lachmann, H Xu, J Krishnan, SI Berger, AR Mazloom, A Ma'ayan Bioinformatics 26 (19), 2438-2444, 2010 | 952 | 2010 |
Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity MM Janas, MK Schlegel, CE Harbison, VO Yilmaz, Y Jiang, R Parmar, ... Nature communications 9 (1), 723, 2018 | 218 | 2018 |
Comparison of somatic mutation calling methods in amplicon and whole exome sequence data H Xu, J DiCarlo, RV Satya, Q Peng, Y Wang BMC genomics 15, 1-10, 2014 | 201 | 2014 |
Oct4 links multiple epigenetic pathways to the pluripotency network J Ding, H Xu, F Faiola, A Ma'ayan, J Wang Cell research 22 (1), 155-167, 2012 | 193 | 2012 |
Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers EY Chen, H Xu, S Gordonov, MP Lim, MH Perkins, A Ma'ayan Bioinformatics 28 (1), 105-111, 2012 | 178 | 2012 |
TET2-driven clonal hematopoiesis and response to canakinumab: an exploratory analysis of the CANTOS randomized clinical trial EC Svensson, A Madar, CD Campbell, Y He, M Sultan, ML Healey, H Xu, ... JAMA cardiology 7 (5), 521-528, 2022 | 157 | 2022 |
Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells H Xu, YS Ang, A Sevilla, IR Lemischka, A Ma'ayan PLoS computational biology 10 (8), e1003777, 2014 | 124 | 2014 |
ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells H Xu, C Baroukh, R Dannenfelser, EY Chen, CM Tan, Y Kou, YE Kim, ... Database 2013, bat045, 2013 | 121 | 2013 |
Reversal of siRNA-mediated gene silencing in vivo I Zlatev, A Castoreno, CR Brown, J Qin, S Waldron, MK Schlegel, ... Nature biotechnology 36 (6), 509-511, 2018 | 76 | 2018 |
Network‐and attribute‐based classifiers can prioritize genes and pathways for autism spectrum disorders and intellectual disability Y Kou, C Betancur, H Xu, JD Buxbaum, A Ma'Ayan American Journal of Medical Genetics Part C: Seminars in Medical Genetics …, 2012 | 43 | 2012 |
Toward a complete in silico, multi‐layered embryonic stem cell regulatory network H Xu, C Schaniel, IR Lemischka, A Ma'ayan Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2 (6), 708-733, 2010 | 34 | 2010 |
SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells H Xu, IR Lemischka, A Ma'ayan BMC systems biology 4, 1-10, 2010 | 33 | 2010 |
Activation of Alternate Pro-Survival Pathways Accounts for Acquired Sunitinib Resistance in U87MG Glioma Xenografts Q Zhou, H Lv, AR Mazloom, H Xu, A Ma'ayan, JM Gallo JPET, 2012 | 21 | 2012 |
GalNAc-siRNA conjugate ALN-HBV targets a highly conserved, pan-genotypic X-orf viral site and mediates profound and durable HBsAg silencing in vitro and in vivo L Sepp-Lorenzino, AG Sprague, T Mayo, TM Nguyen, SS Morskaya, H Xu, ... Hepatology 62, 224A-225A, 2015 | 9 | 2015 |
An esrrb and nanog cell fate regulatory module controlled by feed forward loop interactions A Sevilla, D Papatsenko, AR Mazloom, H Xu, A Vasileva, RD Unwin, ... Frontiers in cell and developmental biology 9, 630067, 2021 | 8 | 2021 |
Sterol regulatory element binding protein (SREBP) chaperone (SCAP) iRNA compositions and methods of use thereof K Fitzgerald, H Xu, G Hinkle US Patent 10,767,177, 2020 | 6 | 2020 |
Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity. Nat Commun 9 (1): 723 MM Janas, MK Schlegel, CE Harbison, VO Yilmaz, Y Jiang, R Parmar, ... | 5 | 2018 |
Quantitative approaches to model pluripotency and differentiation in stem cells D Papatsenko, H Xu, A Ma’ayan, I Lemischka Stem Cells Handbook, 59-74, 2013 | 5 | 2013 |
Effects of IL-1β inhibition on anemia and clonal hematopoiesis in the randomized CANTOS trial J Woo, D Lu, A Lewandowski, H Xu, P Serrano, M Healey, DP Yates, ... Blood Advances 7 (24), 7471-7484, 2023 | 4 | 2023 |
Clinical characteristics of heart failure with reduced ejection fraction patients with rare pathogenic variants in dilated cardiomyopathy‐associated genes: A subgroup analysis … A Barat, CW Chen, N Patel‐Murray, JJV McMurray, M Packer, ... European Journal of Heart Failure 25 (8), 1256-1266, 2023 | 3 | 2023 |