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Signals from the lysosome: a control centre for cellular clearance and energy metabolism C Settembre, A Fraldi, DL Medina, A Ballabio Nature reviews Molecular cell biology 14 (5), 283-296, 2013 | 1715 | 2013 |
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ... Nature cell biology 17 (3), 288-299, 2015 | 1230 | 2015 |
Transcriptional activation of lysosomal exocytosis promotes cellular clearance DL Medina, A Fraldi, V Bouche, F Annunziata, G Mansueto, ... Developmental cell 21 (3), 421-430, 2011 | 770 | 2011 |
Mechanism of TrkB-mediated hippocampal long-term potentiation L Minichiello, AM Calella, DL Medina, T Bonhoeffer, R Klein, M Korte Neuron 36 (1), 121-137, 2002 | 610 | 2002 |
A block of autophagy in lysosomal storage disorders C Settembre, A Fraldi, L Jahreiss, C Spampanato, C Venturi, D Medina, ... Human molecular genetics 17 (1), 119-129, 2008 | 592 | 2008 |
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition A Luciani, VR Villella, S Esposito, N Brunetti-Pierri, D Medina, ... Nature cell biology 12 (9), 863-875, 2010 | 530 | 2010 |
mTOR-dependent phosphorylation controls TFEB nuclear export G Napolitano, A Esposito, H Choi, M Matarese, V Benedetti, C Di Malta, ... Nature communications 9 (1), 3312, 2018 | 326 | 2018 |
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders A Fraldi, F Annunziata, A Lombardi, HJ Kaiser, DL Medina, ... The EMBO journal 29 (21), 3607-3620, 2010 | 243 | 2010 |
FGF signalling regulates bone growth through autophagy L Cinque, A Forrester, R Bartolomeo, M Svelto, R Venditti, S Montefusco, ... Nature 528 (7581), 272-275, 2015 | 195 | 2015 |
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition JX Song, YR Sun, I Peluso, Y Zeng, X Yu, JH Lu, Z Xu, MZ Wang, LF Liu, ... Autophagy 12 (8), 1372-1389, 2016 | 173 | 2016 |
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis SE Mole, G Anderson, HA Band, SF Berkovic, JD Cooper, SMK Holthaus, ... The Lancet Neurology 18 (1), 107-116, 2019 | 168 | 2019 |
Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL MG De Leo, L Staiano, M Vicinanza, A Luciani, A Carissimo, M Mutarelli, ... Nature cell biology 18 (8), 839-850, 2016 | 166 | 2016 |
Brain disorders due to lysosomal dysfunction A Fraldi, AD Klein, DL Medina, C Settembre Annual review of neuroscience 39, 277-295, 2016 | 157 | 2016 |
The rapidly evolving view of lysosomal storage diseases G Parenti, DL Medina, A Ballabio EMBO molecular medicine 13 (2), e12836, 2021 | 146 | 2021 |
TRPML1: The Ca (2+) retaker of the lysosome S Di Paola, A Scotto-Rosato, DL Medina Cell calcium 69, 112-121, 2018 | 139 | 2018 |
The phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activation M Moskot, S Montefusco, J Jakóbkiewicz-Banecka, P Mozolewski, ... Journal of Biological Chemistry 289 (24), 17054-17069, 2014 | 132 | 2014 |