Hepatocyte differentiation KM Olsavsky Goyak, EM Laurenzana, CJ Omiecinski Hepatocytes: Methods and Protocols, 115-138, 2010 | 51 | 2010 |
Use and validation of HT/HC assays to support 21st century toxicity evaluations G Patlewicz, T Simon, K Goyak, RD Phillips, JC Rowlands, SD Seidel, ... Regulatory Toxicology and Pharmacology 65 (2), 259-268, 2013 | 46 | 2013 |
Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures KMO Goyak, MC Johnson, SC Strom, CJ Omiecinski Toxicology and applied pharmacology 231 (2), 216-224, 2008 | 46 | 2008 |
Pathway-based toxicity: History, current approaches, and liver fibrosis and steatosis as prototypes C Willett, JC Rae, KO Goyak, B Landesmann, G Minsavage, ... ALTEX-Alternatives to animal experimentation 31 (4), 407-421, 2014 | 28 | 2014 |
Developing scientific confidence in HTS-derived prediction models: Lessons learned from an endocrine case study LAT Cox, D Popken, MS Marty, JC Rowlands, G Patlewicz, KO Goyak, ... Regulatory Toxicology and Pharmacology 69 (3), 443-450, 2014 | 27 | 2014 |
Evaluating the MoA/human relevance framework for F-344 rat liver epithelioid granulomas with mineral oil hydrocarbons D Adenuga, K Goyak, RJ Lewis Critical Reviews in Toxicology 47 (9), 754-770, 2017 | 24 | 2017 |
Acute, subchronic, and developmental toxicological properties of lubricating oil base stocks WE Dalbey, RH McKee, KO Goyak, RW Biles, J Murray, R White International Journal of Toxicology 33 (1_suppl), 110S-135S, 2014 | 21 | 2014 |
Comparative toxicokinetics of low-viscosity mineral oil in Fischer 344 rats, Sprague–Dawley rats, and humans–Implications for an Acceptable Daily Intake (ADI) PJ Boogaard, KO Goyak, RW Biles, LLP van Stee, MS Miller, MJ Miller Regulatory Toxicology and Pharmacology 63 (1), 69-77, 2012 | 21 | 2012 |
A quantitative screening‐level approach to incorporate chemical exposure and risk into alternative assessment evaluations SM Arnold, B Greggs, KO Goyak, BD Landenberger, AM Mason, ... Integrated environmental assessment and management 13 (6), 1007-1022, 2017 | 20 | 2017 |
Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action C Willett, JC Rae, KO Goyak, G Minsavage, C Westmoreland, M Andersen, ... Altex 31 (4), 500, 2014 | 19 | 2014 |
Applying evidence-based methods to the development and use of adverse outcome pathways RBM De Vries, M Angrish, P Browne, J Brozek, AA Rooney, DS Wikoff, ... Altex 38 (2), 336, 2021 | 17 | 2021 |
Development of a screening tool to prioritize testing for the carcinogenic hazard of residual aromatic extracts and related petroleum streams KO Goyak, MH Kung, M Chen, KK Aldous, JJ Freeman Toxicology Letters 264, 99-105, 2016 | 14 | 2016 |
The toxicological effects of heavy fuel oil category substances RH McKee, F Reitman, C Schreiner, R White, JH Charlap, TP O’Neill, ... International Journal of Toxicology 33 (1_suppl), 95S-109S, 2014 | 11 | 2014 |
Application of adverse outcome pathway networks to integrate mechanistic data informing the choice of a point of departure for hydrogen sulfide exposure limits KO Goyak, RJ Lewis Critical Reviews in Toxicology 51 (3), 193-208, 2021 | 8 | 2021 |
Paving asphalt products exhibit a lack of carcinogenic and mutagenic activity KO Goyak, RH McKee, GD Minsavage, C McGowan, WC Daughtrey, ... International Journal of Toxicology 30 (5), 492-497, 2011 | 8 | 2011 |
Subchronic and developmental toxicity of aromatic extracts WE Dalbey, RH McKee, KO Goyak, JH Charlap, C Parker, R White International Journal of Toxicology 33 (1_suppl), 136S-155S, 2014 | 6 | 2014 |
Applying a scientific confidence framework to a HTS-derived prediction model for endocrine endpoints: lessons learned from a case study LA Cox, D Douglas, S Marty, JC Rowlands, G Patlewicz, KO Goyak, ... Reg. Toxicol. Pharmacol 69, 443-450, 2014 | 5 | 2014 |
Characterization of the noncancer hazards of gas oils RH McKee, CA Schreiner, R White, M Saperstein, JH Charlap, TP O'Neill, ... International Journal of Toxicology 33 (1_suppl), 78S-94S, 2014 | 4 | 2014 |
The last resort requirement under REACH: From principle to practice DS Macmillan, A Bergqvist, E Burgess-Allen, I Callan, J Dawick, B Carrick, ... Regulatory Toxicology and Pharmacology 147, 105557, 2024 | 3 | 2024 |
Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats KO Goyak, SS Sarang, A Franzen, SJ Borghoff, JP Ryman-Rasmussen Critical Reviews in Toxicology 52 (5), 345-357, 2022 | 3 | 2022 |