Structure-based design of prefusion-stabilized SARS-CoV-2 spikes CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ... Science 369 (6510), 1501-1505, 2020 | 1106 | 2020 |
Antibody engineering J Maynard, G Georgiou Annual review of biomedical engineering 2 (1), 339-376, 2000 | 522 | 2000 |
Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity JA Maynard, CBM Maassen, SH Leppla, K Brasky, JL Patterson, ... Nature biotechnology 20 (6), 597-601, 2002 | 384 | 2002 |
Structural evidence for a germline-encoded T cell receptor–major histocompatibility complex interaction'codon' D Feng, CJ Bond, LK Ely, J Maynard, KC Garcia Nature immunology 8 (9), 975-983, 2007 | 251 | 2007 |
Rhizoremediation of Trichloroethylene by a Recombinant, Root-Colonizing Pseudomonas fluorescensStrain Expressing Toluene ortho-Monooxygenase … DC Yee, JA Maynard, TK Wood Applied and Environmental Microbiology 64 (1), 112-118, 1998 | 223 | 1998 |
Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity J Maynard, K Petersson, DH Wilson, EJ Adams, SE Blondelle, ... Immunity 22 (1), 81-92, 2005 | 201 | 2005 |
Surface plasmon resonance for high‐throughput ligand screening of membrane‐bound proteins JA Maynard, NC Lindquist, JN Sutherland, A Lesuffleur, AE Warrington, ... Biotechnology Journal: Healthcare Nutrition Technology 4 (11), 1542-1558, 2009 | 142 | 2009 |
Concentrated dispersions of equilibrium protein nanoclusters that reversibly dissociate into active monomers KP Johnston, JA Maynard, TM Truskett, AU Borwankar, MA Miller, ... ACS nano 6 (2), 1357-1369, 2012 | 140 | 2012 |
In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2–x)/ZnS Core/Shell Quantum Dots MG Panthani, TA Khan, DK Reid, DJ Hellebusch, MR Rasch, JA Maynard, ... Nano letters 13 (9), 4294-4298, 2013 | 123 | 2013 |
Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics H Im, JN Sutherland, JA Maynard, SH Oh Analytical chemistry 84 (4), 1941-1947, 2012 | 120 | 2012 |
A novel all helix fold of the AP180 amino-terminal domain for phosphoinositide binding and clathrin assembly in synaptic vesicle endocytosis Y Mao, J Chen, JA Maynard, B Zhang, FA Quiocho Cell 104 (3), 433-440, 2001 | 111 | 2001 |
When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions ARM Bradbury, ND Trinklein, H Thie, IC Wilkinson, AK Tandon, ... MAbs 10 (4), 539-546, 2018 | 103 | 2018 |
The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes SM Costello, SR Shoemaker, HT Hobbs, AW Nguyen, CL Hsieh, ... Nature Structural & Molecular Biology 29 (3), 229-238, 2022 | 94 | 2022 |
Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing CA Kowalsky, MS Faber, A Nath, HE Dann, VW Kelly, L Liu, P Shanker, ... Journal of Biological Chemistry 290 (44), 26457-26470, 2015 | 94 | 2015 |
Frozen-state storage stability of a monoclonal antibody: aggregation is impacted by freezing rate and solute distribution MA Miller, MA Rodrigues, MA Glass, SK Singh, KP Johnston, JA Maynard Journal of pharmaceutical sciences 102 (4), 1194-1208, 2013 | 93 | 2013 |
Forward engineering of synthetic bio-logical AND gates KI Ramalingam, JR Tomshine, JA Maynard, YN Kaznessis Biochemical Engineering Journal 47 (1-3), 38-47, 2009 | 80 | 2009 |
Recent advances incorporating superparamagnetic nanoparticles into immunoassays Y Ha, S Ko, I Kim, Y Huang, K Mohanty, C Huh, JA Maynard ACS Applied Nano Materials 1 (2), 512-521, 2018 | 70 | 2018 |
A cocktail of humanized anti–pertussis toxin antibodies limits disease in murine and baboon models of whooping cough AW Nguyen, EK Wagner, JR Laber, LL Goodfield, WE Smallridge, ... Science translational medicine 7 (316), 316ra195-316ra195, 2015 | 69 | 2015 |
Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses RP Silva, Y Huang, AW Nguyen, CL Hsieh, OS Olaluwoye, TS Kaoud, ... Elife 12, 2023 | 65* | 2023 |
High-level bacterial secretion of single-chain αβ T-cell receptors J Maynard, EJ Adams, M Krogsgaard, K Petersson, CW Liu, KC Garcia Journal of immunological methods 306 (1-2), 51-67, 2005 | 63 | 2005 |