Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein L He, A Sabet, S Djedjos, R Miller, X Sun, MA Hussain, S Radovick, ... Cell 137 (4), 635-646, 2009 | 605 | 2009 |
Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation J Wang, D Gallagher, LM DeVito, GI Cancino, D Tsui, L He, GM Keller, ... Cell stem cell 11 (1), 23-35, 2012 | 504 | 2012 |
Metformin action: concentrations matter L He, FE Wondisford Cell metabolism 21 (2), 159-162, 2015 | 469 | 2015 |
Metformin improves mitochondrial respiratory activity through activation of AMPK Y Wang, H An, T Liu, C Qin, H Sesaki, S Guo, S Radovick, M Hussain, ... Cell reports 29 (6), 1511-1523. e5, 2019 | 298 | 2019 |
Current understanding of metformin effect on the control of hyperglycemia in diabetes H An, L He The Journal of endocrinology 228 (3), R97, 2016 | 233 | 2016 |
CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain J Wang, ICG Weaver, A Gauthier-Fisher, H Wang, L He, J Yeomans, ... Developmental cell 18 (1), 114-125, 2010 | 223 | 2010 |
Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK)*♦ J Cao, S Meng, E Chang, K Beckwith-Fickas, L Xiong, RN Cole, ... Journal of Biological Chemistry 289 (30), 20435-20446, 2014 | 200 | 2014 |
Metformin activates AMP-activated protein kinase by promoting formation of the αβγ heterotrimeric complex S Meng, J Cao, Q He, L Xiong, E Chang, S Radovick, FE Wondisford, ... Journal of Biological Chemistry 290 (6), 3793-3802, 2015 | 177 | 2015 |
Metformin acts on two different molecular pathways to enhance adult neural precursor proliferation/self-renewal and differentiation M Fatt, K Hsu, L He, F Wondisford, FD Miller, DR Kaplan, J Wang Stem cell reports 5 (6), 988-995, 2015 | 134 | 2015 |
Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane: role of TRB3 in inhibition of Akt/protein kinase B activation L He, FA Simmen, HM Mehendale, MJJ Ronis, TM Badger Journal of Biological Chemistry 281 (16), 11126-11134, 2006 | 128 | 2006 |
Exosomes mediate epithelium–mesenchyme crosstalk in organ development N Jiang, L Xiang, L He, G Yang, J Zheng, C Wang, Y Zhang, S Wang, ... ACS nano 11 (8), 7736-7746, 2017 | 120 | 2017 |
Inhibition of the Interferon-γ/Signal Transducers and Activators of Transcription (STAT) Pathway by Hypermethylation at a STAT-binding Site in the p21 WAF1 Promoter Region B Chen, L He, VH Savell, JJ Jenkins, DM Parham Cancer research 60 (12), 3290-3298, 2000 | 120 | 2000 |
Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats JC Rowlands, L He, R Hakkak, MJJ Ronis, TM Badger The Journal of nutrition 131 (12), 3281-3287, 2001 | 108 | 2001 |
Inhibition of growth and induction of apoptosis in human cancer cell lines by an ethyl acetate fraction from shiitake mushrooms N Fang, Q Li, S Yu, J Zhang, L He, MJJ Ronis, TM Badger Journal of Alternative & Complementary Medicine 12 (2), 125-132, 2006 | 105 | 2006 |
Regenerative endodontics for adult patients L He, SG Kim, Q Gong, J Zhong, S Wang, X Zhou, L Ye, J Ling, JJ Mao Journal of endodontics 43 (9), S57-S64, 2017 | 104 | 2017 |
Interest rate sensitivities of REIT returns LT He, JR Webb, FCN Myer International Real Estate Review 6 (1), 1-21, 2003 | 93 | 2003 |
Novel mechanism of Foxo1 phosphorylation in glucagon signaling in control of glucose homeostasis Y Wu, Q Pan, H Yan, K Zhang, X Guo, Z Xu, W Yang, Y Qi, CA Guo, ... Diabetes 67 (11), 2167-2182, 2018 | 87 | 2018 |
An application of interval methods to stock market forecasting C Hu, LT He Reliable Computing 13 (5), 423-434, 2007 | 74 | 2007 |
Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions CJ Romero, E Pine-Twaddell, DI Sima, RS Miller, L He, F Wondisford, ... Molecular and cellular biology 32 (21), 4258-4269, 2012 | 70 | 2012 |
Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity J Cao, J Peng, H An, Q He, T Boronina, S Guo, MF White, PA Cole, L He Nature Communications 8 (1), 131, 2017 | 63 | 2017 |