Pharmaceuticals from cultured algae RE Schwartz, CF Hirsch, DF Sesin, JE Flor, M Chartrain, RE Fromtling, ... Journal of industrial microbiology and biotechnology 5 (2-3), 113-123, 1990 | 432 | 1990 |
Discovery of Novel Antifungal (1,3)-β-d-Glucan Synthase Inhibitors J Onishi, M Meinz, J Thompson, J Curotto, S Dreikorn, M Rosenbach, ... Antimicrobial agents and chemotherapy 44 (2), 368-377, 2000 | 423 | 2000 |
An activator of calcium-dependent potassium channels isolated from a medicinal herb OB McManus, GH Harris, KM Giangiacomo, P Feigenbaum, JP Reuben, ... Biochemistry 32 (24), 6128-6133, 1993 | 247 | 1993 |
The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella australis producing organism, fermentation, isolation, and biological activity SM Mandala, RA Thornton, BR Frommer, JE Curotto, W Rozdilsky, ... The Journal of antibiotics 48 (5), 349-356, 1995 | 191 | 1995 |
Confronting the challenges of natural product-based antifungal discovery T Roemer, D Xu, SB Singh, CA Parish, G Harris, H Wang, JE Davies, ... Chemistry & biology 18 (2), 148-164, 2011 | 173 | 2011 |
Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase SM Mandala, RA Thornton, J Milligan, M Rosenbach, M Garcia-Calvo, ... Journal of Biological Chemistry 273 (24), 14942-14949, 1998 | 143 | 1998 |
Isolation and structure elucidation of parnafungins, antifungal natural products that inhibit mRNA polyadenylation CA Parish, SK Smith, K Calati, D Zink, K Wilson, T Roemer, B Jiang, D Xu, ... Journal of the American Chemical Society 130 (22), 7060-7066, 2008 | 97 | 2008 |
PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products B Jiang, D Xu, J Allocco, C Parish, J Davison, K Veillette, S Sillaots, W Hu, ... Chemistry & biology 15 (4), 363-374, 2008 | 96 | 2008 |
Chemical genomics-based antifungal drug discovery: targeting glycosylphosphatidylinositol (GPI) precursor biosynthesis PA Mann, CA McLellan, S Koseoglu, Q Si, E Kuzmin, A Flattery, G Harris, ... ACS Infectious Diseases 1 (1), 59-72, 2015 | 84 | 2015 |
Isolation and structure elucidation of viridiofungins A, B and C GH Harris, ETT Jones, MS Meinz, M Nallin-Omstead, GL Helms, GF Bills, ... Tetrahedron letters 34 (33), 5235-5238, 1993 | 79 | 1993 |
Isolation, Structure Elucidation, and Biological Activity of Virgineone from Lachnum virgineum Using the Genome-Wide Candida albicans Fitness Test J Ondeyka, G Harris, D Zink, A Basilio, F Vicente, G Bills, G Platas, ... Journal of natural products 72 (1), 136-141, 2009 | 70 | 2009 |
Comparison of preparative reversed phase liquid chromatography and countercurrent chromatography for the kilogram scale purification of crude spinetoram insecticide C DeAmicis, NA Edwards, MB Giles, GH Harris, P Hewitson, L Janaway, ... Journal of Chromatography A 1218 (36), 6122-6127, 2011 | 69 | 2011 |
Isolation and structure determination of pycnidione, a novel bistropolone stromelysin inhibitor from a Phoma sp. GH Harris, K Hoogsteen, KC Silverman, SL Raghoobar, GF Bills, ... Tetrahedron 49 (11), 2139-2144, 1993 | 69 | 1993 |
[35] Isolation and characterization of novel inhibitors of sphingolipid synthesis: Australifungin, viridiofungins, rustmicin, and khafrefungin SM Mandala, GH Harris Methods in enzymology 311, 335-348, 2000 | 68 | 2000 |
In vitro evidence that eukaryotic ribosomal RNA transcription is regulated by modification of RNA polymerase I MR Paule, CT Iida, PJ Perna, GH Harris, DA Knoll, JM d'Alessio Nucleic Acids Research 12 (21), 8161-8180, 1984 | 67 | 1984 |
Mechanism of maxi-K channel activation by dehydrosoyasaponin-I KM Giangiacomo, A Kamassah, G Harris, OB McManus The Journal of general physiology 112 (4), 485-501, 1998 | 65 | 1998 |
Discovery of the parnafungins, antifungal metabolites that inhibit mRNA polyadenylation, from the Fusarium larvarum complex and other Hypocrealean fungi GF Bills, G Platas, DP Overy, J Collado, A Fillola, MR Jiménez, J Martín, ... Mycologia 101 (4), 449-472, 2009 | 64 | 2009 |
Cholesterol lowering compounds H Joshua, GH Harris US Patent 5,262,435, 1993 | 62* | 1993 |
Distribution of the antifungal agents sordarins across filamentous fungi F Vicente, A Basilio, G Platas, J Collado, GF Bills, AG Del Val, J Martín, ... mycological research 113 (6-7), 754-770, 2009 | 59 | 2009 |
Transfer of pyrrolizidine and quinolizidine alkaloids toCastilleja (Scrophulariaceae) hemiparasites from composite and legume host plants FR Stermitz, GH Harris Journal of Chemical Ecology 13, 1917-1925, 1987 | 59 | 1987 |