| Identification of neutral tumor evolution across cancer types MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva Nature Genetics, 2016 | 657 | 2016 |
| Quantification of subclonal selection in cancer from bulk sequencing data MJ Williams, B Werner, T Heide, C Curtis, CP Barnes, A Sottoriva, ... Nature Genetics, 1, 2018 | 243 | 2018 |
| Evolutionary history of human colitis-associated colorectal cancer AM Baker, W Cross, K Curtius, I Al Bakir, CHR Choi, HL Davis, D Temko, ... Gut, gutjnl-2018-316191, 2018 | 143 | 2018 |
| Clonal fitness inferred from time-series modelling of single-cell cancer genomes S Salehi, F Kabeer, N Ceglia, M Andronescu, MJ Williams, KR Campbell, ... Nature, 1-6, 2021 | 98 | 2021 |
| Subclonal reconstruction of tumors by using machine learning and population genetics G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ... Nature Genetics 52 (9), 898-907, 2020 | 98 | 2020 |
| Evolutionary dynamics of neoantigens in growing tumours E Lakatos, MJ Williams, RO Schenck, WCH Cross, J Househam, ... Nature Genetics 52 (10), 1057-1066, 2020 | 95 | 2020 |
| Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen … D Temko, IC Van Gool, E Rayner, M Glaire, S Makino, M Brown, ... The Journal of pathology, 2018 | 95 | 2018 |
| Ovarian cancer mutational processes drive site-specific immune evasion I Vázquez-García, F Uhlitz, N Ceglia, JLP Lim, M Wu, N Mohibullah, ... Nature, 1-9, 2022 | 94 | 2022 |
| Measuring Clonal Evolution in Cancer with Genomics MJ Williams, A Sottoriva, TA Graham Annual Review of Genomics and Human Genetics 20, 2019 | 81 | 2019 |
| Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data K Chkhaidze, T Heide, B Werner, MJ Williams, W Huang, G Caravagna, ... PLoS Computational Biology 15 (7), e1007243, 2019 | 73 | 2019 |
| Single-cell genomic variation induced by mutational processes in cancer T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ... Nature, 1-10, 2022 | 66* | 2022 |
| Measuring single cell divisions in human tissues from multi-region sequencing data B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ... Nature communications 11 (1), 1-9, 2020 | 64 | 2020 |
| Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology I Sequeira, M Rashid, IM Tomás, MJ Williams, TA Graham, DJ Adams, ... Nature communications 11 (1), 1-13, 2020 | 40 | 2020 |
| Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios MJ Williams, L Zapata, B Werner, C Barnes, A Sottoriva, TA Graham eLife, 661264, 2020 | 39 | 2020 |
| MLH1 deficiency leads to deregulated mitochondrial metabolism S Rashid, MO Freitas, D Cucchi, G Bridge, Z Yao, L Gay, M Williams, ... Cell death & disease 10 (11), 1-11, 2019 | 38 | 2019 |
| Crypt fusion as a homeostatic mechanism in the human colon AM Baker, C Gabbutt, MJ Williams, B Cereser, N Jawad, ... Gut, gutjnl-2018-317540, 2019 | 37 | 2019 |
| Cancer phylogenetic tree inference at scale from 1000s of single cell genomes S Salehi, F Dorri, K Chern, F Kabeer, N Rusk, T Funnell, MJ Williams, ... Peer Community Journal 3, 2023 | 33* | 2023 |
| Reply to ‘Neutral tumor evolution?’ T Heide, L Zapata, MJ Williams, B Werner, G Caravagna, CP Barnes, ... Nature genetics 50 (12), 1633, 2018 | 32 | 2018 |
| Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors L Zapata, G Caravagna, MJ Williams, E Lakatos, K AbdulJabbar, ... Nature Genetics 55 (3), 451-460, 2023 | 31* | 2023 |
| Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer W Cross, M Mossner, S Nowinski, G Cresswell, A Banerjee, M Williams, ... bioRxiv, 2020 | 15 | 2020 |
Trevor A GrahamDirector, Centre for Evolution and Cancer, ICR, London在 icr.ac.uk 的电子邮件经过验证
