Glucocorticoid receptor phosphorylation differentially affects target gene expression W Chen, T Dang, RD Blind, Z Wang, CN Cavasotto, AB Hittelman, ... Molecular Endocrinology 22 (8), 1754-1766, 2008 | 335 | 2008 |
Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation BC Lin, M Suzawa, RD Blind, SC Tobias, SE Bulun, TS Scanlan, ... Cancer research 69 (13), 5415-5423, 2009 | 190 | 2009 |
Differential recruitment of glucocorticoid receptor phospho-isoforms to glucocorticoid-induced genes RD Blind, MJ Garabedian The Journal of steroid biochemistry and molecular biology 109 (1-2), 150-157, 2008 | 152 | 2008 |
Direct modification and activation of a nuclear receptor–PIP2 complex by the inositol lipid kinase IPMK RD Blind, M Suzawa, HA Ingraham Science signaling 5 (229), ra44-ra44, 2012 | 111 | 2012 |
The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1 RD Blind, EP Sablin, KM Kuchenbecker, HJ Chiu, AM Deacon, D Das, ... Proceedings of the National Academy of Sciences 111 (42), 15054-15059, 2014 | 100 | 2014 |
Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2) RJ Whitby, J Stec, RD Blind, S Dixon, LM Leesnitzer, LA Orband-Miller, ... Journal of medicinal chemistry 54 (7), 2266-2281, 2011 | 94 | 2011 |
Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands EP Sablin, RD Blind, IN Krylova, JG Ingraham, F Cai, JD Williams, ... Molecular endocrinology 23 (1), 25-34, 2009 | 92 | 2009 |
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks R Haliyur, X Tong, M Sanyoura, S Shrestha, J Lindner, DC Saunders, ... The Journal of clinical investigation 129 (1), 246-251, 2019 | 84 | 2019 |
Regulation of C. elegans Fat Uptake and Storage by Acyl-CoA Synthase-3 Is Dependent on NR5A Family Nuclear Hormone Receptornhr-25 BC Mullaney, RD Blind, GA Lemieux, CL Perez, IC Elle, NJ Faergeman, ... Cell metabolism 12 (4), 398-410, 2010 | 76 | 2010 |
Stabilization of the unliganded glucocorticoid receptor by TSG101 N Ismaili, R Blind, MJ Garabedian Journal of Biological Chemistry 280 (12), 11120-11126, 2005 | 68 | 2005 |
Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket EP Sablin, RD Blind, R Uthayaruban, HJ Chiu, AM Deacon, D Das, ... Journal of structural biology 192 (3), 342-348, 2015 | 58 | 2015 |
Phospholipid regulation of the nuclear receptor superfamily MK Crowder, CD Seacrist, RD Blind Advances in biological regulation 63, 6-14, 2017 | 44 | 2017 |
Nuclear phosphoinositide regulation of chromatin BL Hamann, RD Blind Journal of cellular physiology 233 (1), 107-123, 2018 | 37 | 2018 |
Inositol polyphosphate multikinase (IPMK) in transcriptional regulation and nuclear inositide metabolism MM Malabanan, RD Blind Biochemical Society Transactions 44 (1), 279-285, 2016 | 34 | 2016 |
Disentangling biological signaling networks by dynamic coupling of signaling lipids to modifying enzymes RD Blind Advances in biological regulation 54, 25-38, 2014 | 33 | 2014 |
Structural analyses of inositol phosphate second messengers bound to signaling effector proteins RD Blind Advances in biological regulation 75, 100667, 2020 | 32 | 2020 |
Integrated structural modeling of full-length LRH-1 reveals inter-domain interactions contribute to receptor structure and function CD Seacrist, G Kuenze, RM Hoffmann, BE Moeller, JE Burke, J Meiler, ... Structure 28 (7), 830-846. e9, 2020 | 27 | 2020 |
Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease JM Bryant, RD Blind Journal of Lipid Research 60 (2), 299-311, 2019 | 17 | 2019 |
Ligand structural motifs can decouple glucocorticoid receptor transcriptional activation from target promoter occupancy RD Blind, I Pineda-Torra, Y Xu, HE Xu, MJ Garabedian Biochemical and biophysical research communications 420 (4), 839-844, 2012 | 13 | 2012 |
Crystallographic and kinetic analyses of human IPMK reveal disordered domains modulate ATP binding and kinase activity CD Seacrist, RD Blind Scientific reports 8 (1), 16672, 2018 | 11 | 2018 |