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Zachariah L. McLean
Zachariah L. McLean
Research Fellow, Massachusetts General Hospital, Harvard Medical School
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Genetic modifiers of Huntington disease differentially influence motor and cognitive domains
JM Lee, Y Huang, M Orth, T Gillis, J Siciliano, E Hong, JS Mysore, ...
The American Journal of Human Genetics 109 (5), 885-899, 2022
492022
Increased MAP kinase inhibition enhances epiblast-specific gene expression in bovine blastocysts
Z McLean, F Meng, H Henderson, P Turner, B Oback
Biology of reproduction 91 (2), 49, 1-10, 2014
412014
Embryo-mediated genome editing for accelerated genetic improvement of livestock
Z McLean, B Oback, G Laible
Frontiers of Agricultural Science and Engineering 7 (2), 148-160, 2020
312020
Testes of DAZL null neonatal sheep lack prospermatogonia but maintain normal somatic cell morphology and marker expression
ZL McLean, SJ Appleby, J Wei, RG Snell, B Oback
Molecular Reproduction and Development 88 (1), 3-14, 2021
102021
Controlled Cytoplast Arrest and Morula Aggregation Enhance Development, Cryoresilience, and In Vivo Survival of Cloned Sheep Embryos
ZL McLean, SJ Appleby, LM Fermin, HV Henderson, J Wei, DN Wells, ...
Cellular Reprogramming 23 (1), 14-25, 2021
72021
Splice modulators target PMS1 to reduce somatic expansion of the Huntington’s disease-associated CAG repeat
ZL McLean, D Gao, K Correia, JCL Roy, S Shibata, IN Farnum, ...
Nature Communications 15 (1), 3182, 2024
62024
Inner Cell Mass Development
B Oback, Z McLean
Encyclopedia of Reproduction (Second Edition) 3, 332-340, 2018
32018
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington’s disease
KH Kim, EP Hong, Y Lee, ZL McLean, E Elezi, R Lee, S Kwak, ...
Proceedings of the National Academy of Sciences 121 (16), e2322924121, 2024
22024
Double cytoplast embryonic cloning improves in vitro but not in vivo development from mitotic pluripotent cells in cattle
SJ Appleby, P Misica‐Turner, FC Oback, A Dhali, ZL McLean, B Oback
Frontiers in Genetics 13, 933534, 2022
22022
Testes of DAZL null sheep lack spermatogonia and maintain normal somatic cells
Z McLean, SJ Appleby, J Wei, RG Snell, B Oback
BioRxiv, 848036, 2019
22019
PMS1 as a target for splice modulation to prevent somatic CAG repeat expansion in Huntington’s disease
ZL McLean, D Gao, K Correia, JCL Roy, S Shibata, IN Farnum, ...
bioRxiv, 2023
12023
Generating cloned sheep embryos by zona-free somatic cell transfer
Z Mclean, S Appleby, L Fermin, B Oback
12020
Germline complementation in sheep
Z McLean
PhD Thesis-University of Auckland, 2020
12020
C014 The influence of rs3512 on miR-124–3p mediated regulation of FAN1 expression
KH Kim, EP Hong, Y Lee, ZL McLean, E Elezi, VC Wheeler, ...
Journal of Neurology, Neurosurgery & Psychiatry 95 (Suppl 1), A30-A31, 2024
2024
Genetic modifiers of somatic expansion and clinical phenotypes in Huntington's disease reveal shared and tissue-specific effects
Genetic Modifiers of Huntington's Disease (GeM-HD) Consortium, JM Lee, ...
bioRxiv, 2024.06. 10.597797, 2024
2024
Front Cover Image, Volume 88, Issue 1, January 2021
ZL McLean, SJ Appleby, J Wei, RG Snell, B Oback
Molecular Reproduction and Development 88 (1), i-i, 2021
2021
Male germline complementation in chimeric sheep
ZL Mclean, RG Snell, BJ Oback
TRANSGENIC RESEARCH 29 (4), 471-471, 2020
2020
‘Natural AI’: towards generating absolute transmitter rams by genome editing and embryo complementation
ZL McLean, RG Snell, B Oback
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