Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation YJ Chai, E Sierecki, VM Tomatis, RS Gormal, N Giles, IC Morrow, D Xia, ... The Journal of cell biology 214 (6), 705, 2016 | 74 | 2016 |
Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin VM Tomatis, A Papadopulos, NT Malintan, S Martin, T Wallis, RS Gormal, ... The Journal of cell biology 200 (3), 301, 2013 | 74 | 2013 |
Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB T Wang, S Martin, TH Nguyen, CB Harper, RS Gormal, ... Nature communications 7 (1), 12976, 2016 | 69 | 2016 |
Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking A Papadopulos, GA Gomez, S Martin, J Jackson, RS Gormal, DJ Keating, ... Nature communications 6 (1), 6297, 2015 | 67 | 2015 |
Trapping of syntaxin1a in presynaptic nanoclusters by a clinically relevant general anesthetic AT Bademosi, J Steeves, S Karunanithi, OH Zalucki, RS Gormal, S Liu, ... Cell reports 22 (2), 427-440, 2018 | 62 | 2018 |
The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming R Kasula, YJ Chai, AT Bademosi, CB Harper, RS Gormal, IC Morrow, ... The Journal of cell biology 214 (7), 847, 2016 | 55 | 2016 |
The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane S Martin, VM Tomatis, A Papadopulos, MP Christie, NT Malintan, ... Journal of cell science 126 (11), 2353-2360, 2013 | 55 | 2013 |
An acto-myosin II constricting ring initiates the fission of activity-dependent bulk endosomes in neurosecretory cells RS Gormal, TH Nguyen, S Martin, A Papadopulos, FA Meunier Journal of Neuroscience 35 (4), 1380-1389, 2015 | 48 | 2015 |
Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies RS Gormal, P Padmanabhan, R Kasula, AT Bademosi, S Coakley, ... Proceedings of the National Academy of Sciences 117 (48), 30476-30487, 2020 | 37 | 2020 |
Increased polyubiquitination and proteasomal degradation of a Munc18-1 disease-linked mutant causes temperature-sensitive defect in exocytosis S Martin, A Papadopulos, VM Tomatis, E Sierecki, NT Malintan, ... Cell reports 9 (1), 206-218, 2014 | 37 | 2014 |
Hericerin derivatives activates a pan‐neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory R Martínez‐Mármol, YJ Chai, JN Conroy, Z Khan, SM Hong, SB Kim, ... Journal of Neurochemistry 165 (6), 791-808, 2023 | 29 | 2023 |
Secretagogue stimulation of neurosecretory cells elicits filopodial extensions uncovering new functional release sites A Papadopulos, S Martin, VM Tomatis, RS Gormal, FA Meunier Journal of Neuroscience 33 (49), 19143-19153, 2013 | 23 | 2013 |
p110δ PI3-kinase inhibition perturbs APP and TNFα trafficking, reduces plaque burden, dampens neuroinflammation, and prevents cognitive decline in an Alzheimer's disease mouse … R Martínez-Mármol, N Mohannak, L Qian, T Wang, RS Gormal, ... Journal of Neuroscience 39 (40), 7976-7991, 2019 | 22 | 2019 |
Super-resolved trajectory-derived nanoclustering analysis using spatiotemporal indexing TP Wallis, A Jiang, K Young, H Hou, K Kudo, AJ McCann, N Durisic, ... Nature communications 14 (1), 3353, 2023 | 15 | 2023 |
Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1‐SV2 plasma membrane nanocluster for synaptic vesicle entry M Joensuu, P Syed, SH Saber, V Lanoue, TP Wallis, J Rae, A Blum, ... The EMBO Journal 42 (13), e112095, 2023 | 10 | 2023 |
A role for tropomyosins in activity-dependent bulk endocytosis? R Gormal, N Valmas, T Fath, F Meunier Molecular and Cellular Neuroscience 84, 112-118, 2017 | 10 | 2017 |
ENA/VASP proteins regulate exocytosis by mediating myosin VI-dependent recruitment of secretory granules to the cortical actin network VM Tomatis, P Josh, A Papadopulos, RS Gormal, V Lanoue, S Martin, ... Molecular and Cellular Neuroscience 84, 100-111, 2017 | 9 | 2017 |
Fyn nanoclustering requires switching to an open conformation and is enhanced by FTLD-Tau biomolecular condensates R Martínez-Mármol, C Small, A Jiang, T Palliyaguru, TP Wallis, ... Molecular Psychiatry 28 (2), 946-962, 2023 | 8 | 2023 |
Molecular videogaming: super-resolved trajectory-based nanoclustering analysis using spatio-temporal indexing TP Wallis, A Jiang, H Hou, RS Gormal, N Durisic, G Balistreri, M Joensuu, ... bioRxiv, 2021.09. 08.459552, 2021 | 8 | 2021 |
Hericerin derivatives from Hericium erinaceus exert BDNF-like neurotrophic activity in central hippocampal neurons and enhance memory R Martínez-Mármol, YJ Chai, Z Khan, SB Kim, SM Hong, RS Gormal, ... bioRxiv, 2020.08. 28.271676, 2020 | 7 | 2020 |