| Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ... The Journal of clinical investigation 127 (6), 2081-2090, 2017 | 195 | 2017 |
| Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting JG Kiselar, PA Janmey, SC Almo, MR Chance Proceedings of the National Academy of Sciences 100 (7), 3942-3947, 2003 | 152 | 2003 |
| Selective PP2A enhancement through biased heterotrimer stabilization D Leonard, W Huang, S Izadmehr, CM O’Connor, DD Wiredja, Z Wang, ... Cell 181 (3), 688-701. e16, 2020 | 149 | 2020 |
| Hydroxyl radical probe of protein surfaces using synchrotron X-ray radiolysis and mass spectrometry JG Kiselar, SD Maleknia, M Sullivan, KM Downard, MR Chance International journal of radiation biology 78 (2), 101-114, 2002 | 148 | 2002 |
| Future directions of structural mass spectrometry using hydroxyl radical footprinting JG Kiselar, MR Chance Journal of mass spectrometry 45 (12), 1373-1382, 2010 | 120 | 2010 |
| Secondary reactions and strategies to improve quantitative protein footprinting G Xu, J Kiselar, Q He, MR Chance Analytical chemistry 77 (10), 3029-3037, 2005 | 117 | 2005 |
| The Beamline X28C of the Center for Synchrotron Biosciences: a national resource for biomolecular structure and dynamics experiments using synchrotron footprinting S Gupta, M Sullivan, J Toomey, J Kiselar, MR Chance Journal of synchrotron radiation 14 (3), 233-243, 2007 | 100 | 2007 |
| Structural analysis of gelsolin using synchrotron protein footprinting JG Kiselar, PA Janmey, SC Almo, MR Chance Molecular & Cellular Proteomics 2 (10), 1120-1132, 2003 | 96 | 2003 |
| Direct Identification of Protein Epitopes by Mass Spectrometry without Immobilization of Antibody and Isolation of Antibody− Peptide Complexes JG Kiselar, KM Downard Analytical chemistry 71 (9), 1792-1801, 1999 | 90 | 1999 |
| Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase SM Stanford, AE Aleshin, V Zhang, RJ Ardecky, MP Hedrick, J Zou, ... Nature chemical biology 13 (6), 624-632, 2017 | 86 | 2017 |
| Antigenic surveillance of the influenza virus by mass spectrometry JG Kiselar, KM Downard Biochemistry 38 (43), 14185-14191, 1999 | 83 | 1999 |
| Small-molecule activators of protein phosphatase 2A for the treatment of castration-resistant prostate cancer K McClinch, RA Avelar, D Callejas, S Izadmehr, D Wiredja, A Perl, ... Cancer research 78 (8), 2065-2080, 2018 | 77 | 2018 |
| GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis JM Goodwin, WG Walkup IV, K Hooper, T Li, C Kishi-Itakura, A Ng, ... Science Advances 7 (40), eabj2485, 2021 | 72 | 2021 |
| Visualizing Arp2/3 complex activation mediated by binding of ATP and WASp using structural mass spectrometry JG Kiselar, R Mahaffy, TD Pollard, SC Almo, MR Chance Proceedings of the National Academy of Sciences 104 (5), 1552-1557, 2007 | 69 | 2007 |
| Preservation and detection of specific antibody—peptide complexes by matrix-assisted laser desorption ionization mass spectrometry JG Kiselar, KM Downard Journal of the American Society for Mass Spectrometry 11 (8), 746-750, 2000 | 67 | 2000 |
| Integrated algorithms for high-throughput examination of covalently labeled biomolecules by structural mass spectrometry P Kaur, JG Kiselar, MR Chance Analytical chemistry 81 (19), 8141-8149, 2009 | 65 | 2009 |
| Quantitative Protein Topography Analysis and High-Resolution Structure Prediction Using Hydroxyl Radical Labeling and Tandem-Ion Mass Spectrometry (MS)*[S] P Kaur, J Kiselar, S Yang, MR Chance Molecular & Cellular Proteomics 14 (4), 1159-1168, 2015 | 62 | 2015 |
| Nerve growth factor regulates transient receptor potential vanilloid 2 via extracellular signal-regulated kinase signaling to enhance neurite outgrowth in developing neurons MR Cohen, WM Johnson, JM Pilat, J Kiselar, A DeFrancesco-Lisowitz, ... Molecular and Cellular Biology 35 (24), 4238-4252, 2015 | 57 | 2015 |
| High-resolution hydroxyl radical protein footprinting: Biophysics tool for drug discovery J Kiselar, MR Chance Annual review of biophysics 47 (1), 315-333, 2018 | 54 | 2018 |
| Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains W Huang, Y Peng, J Kiselar, X Zhao, A Albaqami, D Mendez, Y Chen, ... Nature communications 9 (1), 3520, 2018 | 51 | 2018 |
