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Po-Ru Loh
Po-Ru Loh
Brigham and Women's Hospital / Harvard Medical School
在 broadinstitute.org 的电子邮件经过验证 - 首页
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引用次数
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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
BK Bulik-Sullivan, PR Loh, HK Finucane, S Ripke, J Yang, ...
Nature genetics 47 (3), 291-295, 2015
44132015
Fast, sensitive and accurate integration of single-cell data with Harmony
I Korsunsky, N Millard, J Fan, K Slowikowski, F Zhang, K Wei, ...
Nature methods 16 (12), 1289-1296, 2019
41302019
An atlas of genetic correlations across human diseases and traits
B Bulik-Sullivan, HK Finucane, V Anttila, A Gusev, FR Day, PR Loh, ...
Nature genetics 47 (11), 1236-1241, 2015
34702015
Next-generation genotype imputation service and methods
S Das, L Forer, S Schönherr, C Sidore, AE Locke, A Kwong, SI Vrieze, ...
Nature genetics 48 (10), 1284-1287, 2016
32882016
Partitioning heritability by functional annotation using genome-wide association summary statistics
HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ...
Nature genetics 47 (11), 1228-1235, 2015
22202015
Efficient Bayesian mixed-model analysis increases association power in large cohorts
PR Loh, G Tucker, BK Bulik-Sullivan, BJ Vilhjálmsson, HK Finucane, ...
Nature genetics 47 (3), 284-290, 2015
15412015
Reference-based phasing using the Haplotype Reference Consortium panel
PR Loh, P Danecek, PF Palamara, C Fuchsberger, Y A Reshef, ...
Nature genetics 48 (11), 1443-1448, 2016
15312016
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
13352015
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
HK Finucane, YA Reshef, V Anttila, K Slowikowski, A Gusev, A Byrnes, ...
Nature genetics 50 (4), 621-629, 2018
8902018
Leveraging polygenic functional enrichment to improve GWAS power
G Kichaev, G Bhatia, PR Loh, S Gazal, K Burch, MK Freund, A Schoech, ...
The American Journal of Human Genetics 104 (1), 65-75, 2019
8312019
Mixed-model association for biobank-scale datasets
PR Loh, G Kichaev, S Gazal, AP Schoech, AL Price
Nature genetics 50 (7), 906-908, 2018
6302018
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
FR Day, DJ Thompson, H Helgason, DI Chasman, H Finucane, P Sulem, ...
Nature genetics 49 (6), 834-841, 2017
5052017
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
PR Loh, G Bhatia, A Gusev, HK Finucane, BK Bulik-Sullivan, SJ Pollack, ...
Nature genetics 47 (12), 1385-1392, 2015
5002015
Inferring admixture histories of human populations using linkage disequilibrium
PR Loh, M Lipson, N Patterson, P Moorjani, JK Pickrell, D Reich, B Berger
Genetics 193 (4), 1233-1254, 2013
4882013
Genome-wide associations for birth weight and correlations with adult disease
M Horikoshi, RN Beaumont, FR Day, NM Warrington, MN Kooijman, ...
Nature 538 (7624), 248-252, 2016
4672016
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
NM Warrington, RN Beaumont, M Horikoshi, FR Day, Ø Helgeland, ...
Nature genetics 51 (5), 804-814, 2019
4662019
Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ...
Nature genetics 49 (10), 1421-1427, 2017
4322017
Fast and accurate long-range phasing in a UK Biobank cohort
PR Loh, PF Palamara, AL Price
Nature genetics 48 (7), 811-816, 2016
3652016
Fast principal-component analysis reveals convergent evolution of ADH1B in Europe and East Asia
KJ Galinsky, G Bhatia, PR Loh, S Georgiev, S Mukherjee, NJ Patterson, ...
The American Journal of Human Genetics 98 (3), 456-472, 2016
3632016
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
3462022
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