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Tim Coorens
Tim Coorens
Broad Institute of MIT and Harvard
在 broadinstitute.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
The landscape of somatic mutation in normal colorectal epithelial cells
H Lee-Six, S Olafsson, P Ellis, RJ Osborne, MA Sanders, L Moore, ...
Nature 574 (7779), 532-537, 2019
5942019
Tobacco smoking and somatic mutations in human bronchial epithelium
K Yoshida, KHC Gowers, H Lee-Six, DP Chandrasekharan, T Coorens, ...
Nature 578 (7794), 266-272, 2020
4152020
The mutational landscape of normal human endometrial epithelium
L Moore, D Leongamornlert, THH Coorens, MA Sanders, P Ellis, ...
Nature 580 (7805), 640-646, 2020
4052020
Somatic mutation landscapes at single-molecule resolution
F Abascal, LMR Harvey, E Mitchell, ARJ Lawson, SV Lensing, P Ellis, ...
Nature 593 (7859), 405-410, 2021
3352021
Somatic mutation rates scale with lifespan across mammals
A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ...
Nature 604 (7906), 517-524, 2022
2952022
The mutational landscape of human somatic and germline cells
L Moore, A Cagan, THH Coorens, MDC Neville, R Sanghvi, MA Sanders, ...
Nature 597 (7876), 381-386, 2021
2402021
Extensive heterogeneity in somatic mutation and selection in the human bladder
ARJ Lawson, F Abascal, THH Coorens, Y Hooks, L O’Neill, C Latimer, ...
Science 370 (6512), 75-82, 2020
2332020
Clonal dynamics of haematopoiesis across the human lifespan
E Mitchell, M Spencer Chapman, N Williams, KJ Dawson, N Mende, ...
Nature 606 (7913), 343-350, 2022
2292022
Inherent mosaicism and extensive mutation of human placentas
THH Coorens, TRW Oliver, R Sanghvi, U Sovio, E Cook, R Vento-Tormo, ...
Nature 592 (7852), 80-85, 2021
1642021
Somatic evolution in non-neoplastic IBD-affected colon
S Olafsson, RE McIntyre, T Coorens, T Butler, H Jung, PS Robinson, ...
Cell 182 (3), 672-684. e11, 2020
1512020
Embryonal precursors of Wilms tumor
THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ...
Science 366 (6470), 1247-1251, 2019
1282019
Increased somatic mutation burdens in normal human cells due to defective DNA polymerases
PS Robinson, THH Coorens, C Palles, E Mitchell, F Abascal, S Olafsson, ...
Nature genetics 53 (10), 1434-1442, 2021
1252021
Lineage tracing of human development through somatic mutations
M Spencer Chapman, AM Ranzoni, B Myers, N Williams, THH Coorens, ...
Nature 595 (7865), 85-90, 2021
1162021
Extensive phylogenies of human development inferred from somatic mutations
THH Coorens, L Moore, PS Robinson, R Sanghvi, J Christopher, ...
Nature 597 (7876), 387-392, 2021
1102021
Convergent somatic mutations in metabolism genes in chronic liver disease
SWK Ng, FJ Rouhani, SF Brunner, N Brzozowska, SJ Aitken, M Yang, ...
Nature 598 (7881), 473-478, 2021
1072021
The origins and vulnerabilities of two transmissible cancers in Tasmanian devils
MR Stammnitz, THH Coorens, KC Gori, D Hayes, B Fu, J Wang, ...
Cancer cell 33 (4), 607-619. e15, 2018
1072018
Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing
P Ellis, L Moore, MA Sanders, TM Butler, SF Brunner, H Lee-Six, ...
Nature Protocols 16 (2), 841-871, 2021
972021
A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre
MA Molè, THH Coorens, MN Shahbazi, A Weberling, BAT Weatherbee, ...
Nature communications 12 (1), 3679, 2021
862021
Genetic and chemotherapeutic influences on germline hypermutation
J Kaplanis, B Ide, R Sanghvi, M Neville, P Danecek, T Coorens, ...
Nature 605 (7910), 503-508, 2022
61*2022
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours
L Custers, E Khabirova, THH Coorens, TRW Oliver, C Calandrini, ...
Nature communications 12 (1), 1407, 2021
522021
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