The landscape of somatic mutation in normal colorectal epithelial cells H Lee-Six, S Olafsson, P Ellis, RJ Osborne, MA Sanders, L Moore, ... Nature 574 (7779), 532-537, 2019 | 594 | 2019 |
Tobacco smoking and somatic mutations in human bronchial epithelium K Yoshida, KHC Gowers, H Lee-Six, DP Chandrasekharan, T Coorens, ... Nature 578 (7794), 266-272, 2020 | 415 | 2020 |
The mutational landscape of normal human endometrial epithelium L Moore, D Leongamornlert, THH Coorens, MA Sanders, P Ellis, ... Nature 580 (7805), 640-646, 2020 | 405 | 2020 |
Somatic mutation landscapes at single-molecule resolution F Abascal, LMR Harvey, E Mitchell, ARJ Lawson, SV Lensing, P Ellis, ... Nature 593 (7859), 405-410, 2021 | 335 | 2021 |
Somatic mutation rates scale with lifespan across mammals A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ... Nature 604 (7906), 517-524, 2022 | 295 | 2022 |
The mutational landscape of human somatic and germline cells L Moore, A Cagan, THH Coorens, MDC Neville, R Sanghvi, MA Sanders, ... Nature 597 (7876), 381-386, 2021 | 240 | 2021 |
Extensive heterogeneity in somatic mutation and selection in the human bladder ARJ Lawson, F Abascal, THH Coorens, Y Hooks, L O’Neill, C Latimer, ... Science 370 (6512), 75-82, 2020 | 233 | 2020 |
Clonal dynamics of haematopoiesis across the human lifespan E Mitchell, M Spencer Chapman, N Williams, KJ Dawson, N Mende, ... Nature 606 (7913), 343-350, 2022 | 229 | 2022 |
Inherent mosaicism and extensive mutation of human placentas THH Coorens, TRW Oliver, R Sanghvi, U Sovio, E Cook, R Vento-Tormo, ... Nature 592 (7852), 80-85, 2021 | 164 | 2021 |
Somatic evolution in non-neoplastic IBD-affected colon S Olafsson, RE McIntyre, T Coorens, T Butler, H Jung, PS Robinson, ... Cell 182 (3), 672-684. e11, 2020 | 151 | 2020 |
Embryonal precursors of Wilms tumor THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ... Science 366 (6470), 1247-1251, 2019 | 128 | 2019 |
Increased somatic mutation burdens in normal human cells due to defective DNA polymerases PS Robinson, THH Coorens, C Palles, E Mitchell, F Abascal, S Olafsson, ... Nature genetics 53 (10), 1434-1442, 2021 | 125 | 2021 |
Lineage tracing of human development through somatic mutations M Spencer Chapman, AM Ranzoni, B Myers, N Williams, THH Coorens, ... Nature 595 (7865), 85-90, 2021 | 116 | 2021 |
Extensive phylogenies of human development inferred from somatic mutations THH Coorens, L Moore, PS Robinson, R Sanghvi, J Christopher, ... Nature 597 (7876), 387-392, 2021 | 110 | 2021 |
Convergent somatic mutations in metabolism genes in chronic liver disease SWK Ng, FJ Rouhani, SF Brunner, N Brzozowska, SJ Aitken, M Yang, ... Nature 598 (7881), 473-478, 2021 | 107 | 2021 |
The origins and vulnerabilities of two transmissible cancers in Tasmanian devils MR Stammnitz, THH Coorens, KC Gori, D Hayes, B Fu, J Wang, ... Cancer cell 33 (4), 607-619. e15, 2018 | 107 | 2018 |
Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing P Ellis, L Moore, MA Sanders, TM Butler, SF Brunner, H Lee-Six, ... Nature Protocols 16 (2), 841-871, 2021 | 97 | 2021 |
A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre MA Molè, THH Coorens, MN Shahbazi, A Weberling, BAT Weatherbee, ... Nature communications 12 (1), 3679, 2021 | 86 | 2021 |
Genetic and chemotherapeutic influences on germline hypermutation J Kaplanis, B Ide, R Sanghvi, M Neville, P Danecek, T Coorens, ... Nature 605 (7910), 503-508, 2022 | 61* | 2022 |
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours L Custers, E Khabirova, THH Coorens, TRW Oliver, C Calandrini, ... Nature communications 12 (1), 1407, 2021 | 52 | 2021 |