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Marino Convertino
Marino Convertino
Design Therapeutics
在 parion.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor
R Scherzer-Attali, R Pellarin, M Convertino, A Frydman-Marom, ...
PLoS one 5 (6), e11101, 2010
1792010
9, 10‐Anthraquinone hinders β‐aggregation: How does a small molecule interfere with Aβ‐peptide amyloid fibrillation?
M Convertino, R Pellarin, M Catto, A Carotti, A Caflisch
Protein Science 18 (4), 792-800, 2009
1242009
miRNA-711 binds and activates TRPA1 extracellularly to evoke acute and chronic pruritus
Q Han, D Liu, M Convertino, Z Wang, C Jiang, YH Kim, X Luo, X Zhang, ...
Neuron 99 (3), 449-463. e6, 2018
1092018
Pharmacological chaperones: design and development of new therapeutic strategies for the treatment of conformational diseases
M Convertino, J Das, NV Dokholyan
ACS chemical biology 11 (6), 1471-1489, 2016
1062016
Carnosine Inhibits Aβ42 Aggregation by Perturbing the H‐Bond Network in and around the Central Hydrophobic Cluster
F Attanasio, M Convertino, A Magno, A Caflisch, A Corazza, H Haridas, ...
ChemBioChem 14 (5), 583-592, 2013
922013
Reversible and tunable photoswitching of protein function through genetic encoding of azobenzene amino acids in mammalian cells
J Luo, S Samanta, M Convertino, NV Dokholyan, A Deiters
ChemBioChem 19 (20), 2178-2185, 2018
582018
COMT gene locus: new functional variants
CB Meloto, SK Segall, S Smith, M Parisien, SA Shabalina, ...
Pain 156 (10), 2072-2083, 2015
542015
Disordered binding of small molecules to Aβ (12–28)
M Convertino, A Vitalis, A Caflisch
Journal of Biological Chemistry 286 (48), 41578-41588, 2011
502011
Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling
A Samoshkin, M Convertino, CT Viet, JS Wieskopf, O Kambur, J Marcovitz, ...
Scientific reports 5 (1), 18198, 2015
482015
The molecular basis for dual fatty acid amide hydrolase (FAAH)/cyclooxygenase (COX) inhibition
G Palermo, AD Favia, M Convertino, M De Vivo
ChemMedChem 11 (12), 1252-1258, 2016
422016
μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids
M Convertino, A Samoshkin, J Gauthier, MS Gold, W Maixner, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 62, 61-67, 2015
422015
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512
G Palermo, E Minniti, ML Greco, L Riccardi, E Simoni, M Convertino, ...
Chemical communications 51 (76), 14310-14313, 2015
392015
Differences in the antinociceptive effects and binding properties of propranolol and bupranolol enantiomers
LJ Martin, MH Piltonen, J Gauthier, M Convertino, EL Acland, ...
The Journal of Pain 16 (12), 1321-1333, 2015
342015
Structural basis for inhibiting β-amyloid oligomerization by a non-coded β-breaker-substituted endomorphin analogue
A Frydman-Marom, M Convertino, R Pellarin, A Lampel, R Shaltiel-Karyo, ...
ACS Chemical Biology 6 (11), 1265-1276, 2011
342011
Discovery of novel adenosine receptor antagonists through a combined structure-and ligand-based approach followed by molecular dynamics investigation of ligand binding mode
P Lagarias, E Vrontaki, G Lambrinidis, D Stamatis, M Convertino, G Ortore, ...
Journal of Chemical Information and Modeling 58 (4), 794-815, 2018
262018
ApoE4-specific misfolded intermediate identified by molecular dynamics simulations
B Williams II, M Convertino, J Das, NV Dokholyan
PLoS computational biology 11 (10), e1004359, 2015
262015
Methylations of tryptophan-modified naphthoquinone affect its inhibitory potential toward Aβ aggregation
R Scherzer-Attali, M Convertino, R Pellarin, E Gazit, D Segal, A Caflisch
The Journal of Physical Chemistry B 117 (6), 1780-1789, 2013
192013
Docking and scoring with target-specific pose classifier succeeds in native-like pose identification but not binding affinity prediction in the CSAR 2014 benchmark exercise
R Politi, M Convertino, K Popov, NV Dokholyan, A Tropsha
Journal of Chemical Information and Modeling 56 (6), 1032-1041, 2016
182016
Differential regulation of 6-and 7-transmembrane helix variants of μ-opioid receptor in response to morphine stimulation
M Convertino, A Samoshkin, CT Viet, J Gauthier, SP Li Fraine, ...
PLoS One 10 (11), e0142826, 2015
182015
Molecular insights into hERG potassium channel blockade by lubeluzole
R Gualdani, MM Cavalluzzi, F Tadini-Buoninsegni, M Convertino, P Gailly, ...
Cellular Physiology and Biochemistry 45 (6), 2233-2245, 2018
142018
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