Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor R Scherzer-Attali, R Pellarin, M Convertino, A Frydman-Marom, ... PLoS one 5 (6), e11101, 2010 | 179 | 2010 |
9, 10‐Anthraquinone hinders β‐aggregation: How does a small molecule interfere with Aβ‐peptide amyloid fibrillation? M Convertino, R Pellarin, M Catto, A Carotti, A Caflisch Protein Science 18 (4), 792-800, 2009 | 124 | 2009 |
miRNA-711 binds and activates TRPA1 extracellularly to evoke acute and chronic pruritus Q Han, D Liu, M Convertino, Z Wang, C Jiang, YH Kim, X Luo, X Zhang, ... Neuron 99 (3), 449-463. e6, 2018 | 109 | 2018 |
Pharmacological chaperones: design and development of new therapeutic strategies for the treatment of conformational diseases M Convertino, J Das, NV Dokholyan ACS chemical biology 11 (6), 1471-1489, 2016 | 106 | 2016 |
Carnosine Inhibits Aβ42 Aggregation by Perturbing the H‐Bond Network in and around the Central Hydrophobic Cluster F Attanasio, M Convertino, A Magno, A Caflisch, A Corazza, H Haridas, ... ChemBioChem 14 (5), 583-592, 2013 | 92 | 2013 |
Reversible and tunable photoswitching of protein function through genetic encoding of azobenzene amino acids in mammalian cells J Luo, S Samanta, M Convertino, NV Dokholyan, A Deiters ChemBioChem 19 (20), 2178-2185, 2018 | 58 | 2018 |
COMT gene locus: new functional variants CB Meloto, SK Segall, S Smith, M Parisien, SA Shabalina, ... Pain 156 (10), 2072-2083, 2015 | 54 | 2015 |
Disordered binding of small molecules to Aβ (12–28) M Convertino, A Vitalis, A Caflisch Journal of Biological Chemistry 286 (48), 41578-41588, 2011 | 50 | 2011 |
Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling A Samoshkin, M Convertino, CT Viet, JS Wieskopf, O Kambur, J Marcovitz, ... Scientific reports 5 (1), 18198, 2015 | 48 | 2015 |
The molecular basis for dual fatty acid amide hydrolase (FAAH)/cyclooxygenase (COX) inhibition G Palermo, AD Favia, M Convertino, M De Vivo ChemMedChem 11 (12), 1252-1258, 2016 | 42 | 2016 |
μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids M Convertino, A Samoshkin, J Gauthier, MS Gold, W Maixner, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 62, 61-67, 2015 | 42 | 2015 |
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512 G Palermo, E Minniti, ML Greco, L Riccardi, E Simoni, M Convertino, ... Chemical communications 51 (76), 14310-14313, 2015 | 39 | 2015 |
Differences in the antinociceptive effects and binding properties of propranolol and bupranolol enantiomers LJ Martin, MH Piltonen, J Gauthier, M Convertino, EL Acland, ... The Journal of Pain 16 (12), 1321-1333, 2015 | 34 | 2015 |
Structural basis for inhibiting β-amyloid oligomerization by a non-coded β-breaker-substituted endomorphin analogue A Frydman-Marom, M Convertino, R Pellarin, A Lampel, R Shaltiel-Karyo, ... ACS Chemical Biology 6 (11), 1265-1276, 2011 | 34 | 2011 |
Discovery of novel adenosine receptor antagonists through a combined structure-and ligand-based approach followed by molecular dynamics investigation of ligand binding mode P Lagarias, E Vrontaki, G Lambrinidis, D Stamatis, M Convertino, G Ortore, ... Journal of Chemical Information and Modeling 58 (4), 794-815, 2018 | 26 | 2018 |
ApoE4-specific misfolded intermediate identified by molecular dynamics simulations B Williams II, M Convertino, J Das, NV Dokholyan PLoS computational biology 11 (10), e1004359, 2015 | 26 | 2015 |
Methylations of tryptophan-modified naphthoquinone affect its inhibitory potential toward Aβ aggregation R Scherzer-Attali, M Convertino, R Pellarin, E Gazit, D Segal, A Caflisch The Journal of Physical Chemistry B 117 (6), 1780-1789, 2013 | 19 | 2013 |
Docking and scoring with target-specific pose classifier succeeds in native-like pose identification but not binding affinity prediction in the CSAR 2014 benchmark exercise R Politi, M Convertino, K Popov, NV Dokholyan, A Tropsha Journal of Chemical Information and Modeling 56 (6), 1032-1041, 2016 | 18 | 2016 |
Differential regulation of 6-and 7-transmembrane helix variants of μ-opioid receptor in response to morphine stimulation M Convertino, A Samoshkin, CT Viet, J Gauthier, SP Li Fraine, ... PLoS One 10 (11), e0142826, 2015 | 18 | 2015 |
Molecular insights into hERG potassium channel blockade by lubeluzole R Gualdani, MM Cavalluzzi, F Tadini-Buoninsegni, M Convertino, P Gailly, ... Cellular Physiology and Biochemistry 45 (6), 2233-2245, 2018 | 14 | 2018 |