Therapeutic siRNA: state of the art B Hu, L Zhong, Y Weng, L Peng, Y Huang, Y Zhao, XJ Liang Signal transduction and targeted therapy 5 (1), 101, 2020 | 1014 | 2020 |
Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte S Guo, Y Huang, Q Jiang, Y Sun, L Deng, Z Liang, Q Du, J Xing, Y Zhao, ... ACS nano 4 (9), 5505-5511, 2010 | 467 | 2010 |
Preclinical and clinical advances of GalNAc-decorated nucleic acid therapeutics Y Huang Molecular Therapy-Nucleic Acids 6, 116-132, 2017 | 301 | 2017 |
The challenge and prospect of mRNA therapeutics landscape Y Weng, C Li, T Yang, B Hu, M Zhang, S Guo, H Xiao, XJ Liang, Y Huang Biotechnology advances 40, 107534, 2020 | 282 | 2020 |
Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu, L Wang, T Sun, N Li, L Han, ... Chinese chemical letters 34 (2), 107518, 2023 | 278 | 2023 |
RNAi therapeutic and its innovative biotechnological evolution Y Weng, H Xiao, J Zhang, XJ Liang, Y Huang Biotechnology advances 37 (5), 801-825, 2019 | 274 | 2019 |
Multifunctional aptamer-based nanoparticles for targeted drug delivery to circumvent cancer resistance J Liu, T Wei, J Zhao, Y Huang, H Deng, A Kumar, C Wang, Z Liang, X Ma, ... Biomaterials 91, 44-56, 2016 | 215 | 2016 |
Adaptive amphiphilic dendrimer‐based nanoassemblies as robust and versatile siRNA delivery systems X Liu, J Zhou, T Yu, C Chen, Q Cheng, K Sengupta, Y Huang, H Li, C Liu, ... Angewandte Chemie International Edition 53 (44), 11822-11827, 2014 | 213 | 2014 |
Bioinspired exosome-like therapeutics and delivery nanoplatforms M Lu, Y Huang Biomaterials 242, 119925, 2020 | 211 | 2020 |
An estrogen receptor α suppressor, microRNA‐22, is downregulated in estrogen receptor α‐positive human breast cancer cell lines and clinical samples J Xiong, D Yu, N Wei, H Fu, T Cai, Y Huang, C Wu, X Zheng, Q Du, D Lin, ... The FEBS journal 277 (7), 1684-1694, 2010 | 193 | 2010 |
Functionalized nanoscale micelles improve drug delivery for cancer therapy in vitro and in vivo T Wei, J Liu, H Ma, Q Cheng, Y Huang, J Zhao, S Huo, X Xue, Z Liang, ... Nano letters 13 (6), 2528-2534, 2013 | 187 | 2013 |
Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice J Zhou, CP Neff, X Liu, J Zhang, H Li, DD Smith, P Swiderski, T Aboellail, ... Molecular Therapy 19 (12), 2228-2238, 2011 | 186 | 2011 |
A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy Y Dong, T Yu, L Ding, E Laurini, Y Huang, M Zhang, Y Weng, S Lin, ... Journal of the American Chemical Society 140 (47), 16264-16274, 2018 | 183 | 2018 |
Elimination pathways of systemically delivered siRNA Y Huang, J Hong, S Zheng, Y Ding, S Guo, H Zhang, X Zhang, Q Du, ... Molecular Therapy 19 (2), 381-385, 2011 | 168 | 2011 |
Clinical advances of siRNA therapeutics B Hu, Y Weng, XH Xia, X Liang, Y Huang The journal of gene medicine 21 (7), e3097, 2019 | 162 | 2019 |
Membrane‐destabilizing ionizable lipid empowered imaging‐guided siRNA delivery and cancer treatment S Guo, K Li, B Hu, C Li, M Zhang, A Hussain, X Wang, Q Cheng, F Yang, ... Exploration 1 (1), 35-49, 2021 | 130 | 2021 |
Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly (2-(dimethylamino) ethyl methacrylate)) as an effective gene carrier S Guo, Y Huang, T Wei, W Zhang, W Wang, D Lin, X Zhang, A Kumar, ... Biomaterials 32 (3), 879-889, 2011 | 121 | 2011 |
Intracellular cleavable poly (2-dimethylaminoethyl methacrylate) functionalized mesoporous silica nanoparticles for efficient siRNA delivery in vitro and in vivo D Lin, Q Cheng, Q Jiang, Y Huang, Z Yang, S Han, Y Zhao, S Guo, ... Nanoscale 5 (10), 4291-4301, 2013 | 111 | 2013 |
Enhanced endosomal/lysosomal escape by distearoyl phosphoethanolamine-polycarboxybetaine lipid for systemic delivery of siRNA Y Li, Q Cheng, Q Jiang, Y Huang, H Liu, Y Zhao, W Cao, G Ma, F Dai, ... Journal of controlled release 176, 104-114, 2014 | 109 | 2014 |
Ultrabright and multicolorful fluorescence of amphiphilic polyethyleneimine polymer dots for efficiently combined imaging and therapy Y Sun, W Cao, S Li, S Jin, K Hu, L Hu, Y Huang, X Gao, Y Wu, XJ Liang Scientific reports 3 (1), 3036, 2013 | 98 | 2013 |