The aryl hydrocarbon receptor (AhR) as a breast cancer drug target JR Baker, JA Sakoff, A McCluskey Medicinal research reviews 40 (3), 972-1001, 2020 | 52 | 2020 |
Role of clathrin and dynamin in clathrin mediated endocytosis/synaptic vesicle recycling and implications in neurological diseases KL Prichard, NS O'Brien, SR Murcia, JR Baker, A McCluskey Frontiers in Cellular Neuroscience 15, 754110, 2022 | 27 | 2022 |
Dichlorophenylacrylonitriles as AhR ligands that display selective breast cancer cytotoxicity in vitro JR Baker, J Gilbert, S Paula, X Zhu, JA Sakoff, A McCluskey ChemMedChem 13 (14), 1447-1458, 2018 | 26 | 2018 |
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs) ED Vita Chemical Communications 58 (78), 10933-10936, 2022 | 18 | 2022 |
In situ epoxide generation by dimethyldioxirane oxidation and the use of epichlorohydrin in the flow synthesis of a library of β-amino alcohols PJ Cossar, JR Baker, N Cain, A McCluskey Royal Society open science 5 (4), 171190, 2018 | 15 | 2018 |
In vitro Activity of Robenidine Analog NCL195 in Combination With Outer Membrane Permeabilizers Against Gram-Negative Bacterial Pathogens and Impact on … H Pi, HT Nguyen, H Venter, AR Boileau, L Woolford, S Garg, SW Page, ... Frontiers in Microbiology 11, 1556, 2020 | 14 | 2020 |
Modelling and Phenotypic Screening of NAP‐6 and 10‐Cl‐BBQ, AhR Ligands Displaying Selective Breast Cancer Cytotoxicity in Vitro JR Baker, BL Pollard, AJS Lin, J Gilbert, S Paula, X Zhu, JA Sakoff, ... ChemMedChem 16 (9), 1499-1512, 2021 | 13 | 2021 |
Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents JR Baker, CC Russell, J Gilbert, A McCluskey, JA Sakoff RSC medicinal chemistry 12 (6), 929-942, 2021 | 12 | 2021 |
Amino alcohol acrylonitriles as activators of the aryl hydrocarbon receptor pathway: An unexpected MTT phenotypic screening outcome JR Baker, CC Russell, J Gilbert, JA Sakoff, A McCluskey ChemMedChem 15 (6), 490-505, 2020 | 12 | 2020 |
Gram‐Positive and Gram‐Negative Antibiotic Activity of Asymmetric and Monomeric Robenidine Analogues CC Russell, A Stevens, H Pi, M Khazandi, AD Ogunniyi, KA Young, ... ChemMedChem 13 (23), 2573-2580, 2018 | 12 | 2018 |
FAST hydrogenations as a continuous platform for green aromatic nitroreductions MDT Rahman, S Wharry, M Smyth, H Manyar, TS Moody Synlett 31 (06), 581-586, 2020 | 9 | 2020 |
A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone A Ghods, J Gilbert, JR Baker, CC Russell, JA Sakoff, A McCluskey Royal Society Open Science 5 (4), 171189, 2018 | 9 | 2018 |
Systematic literature review reveals suboptimal use of chemical probes in cell-based biomedical research J Sterling, JR Baker, A McCluskey, L Munoz Nature Communications 14 (1), 3228, 2023 | 8 | 2023 |
Development and interpretation of a QSAR model for in vitro breast cancer (MCF-7) cytotoxicity of 2-phenylacrylonitriles DT Stanton, JR Baker, A McCluskey, S Paula Journal of Computer-Aided Molecular Design 35 (5), 613-628, 2021 | 8 | 2021 |
5-Aryl-2-(naphtha-1-yl) sulfonamido-thiazol-4 (5 H)-ones as clathrin inhibitors MJ Robertson, A Horatscheck, S Sauer, L von Kleist, JR Baker, ... Organic & Biomolecular Chemistry 14 (47), 11266-11278, 2016 | 8 | 2016 |
3, 5-Bis (trifluoromethyl) phenylsulfonamides, a novel pancreatic cancer active lead. Investigation of the terminal aromatic moiety J Sun, JI Ambrus, JR Baker, CC Russell, PJ Cossar, JA Sakoff, CJ Scarlett, ... Bioorganic & Medicinal Chemistry Letters 61, 128591, 2022 | 5 | 2022 |
Discovery of 4,6‐bis(2‐((E)‐benzylidene)hydrazinyl)pyrimidin‐2‐Amine with Antibiotic Activity CC Russell, A Stevens, KA Young, JR Baker, SN McCluskey, M Khazandi, ... ChemistryOpen 8 (7), 896-907, 2019 | 5 | 2019 |
Binding of chlorinated phenylacrylonitriles to the aryl hydrocarbon receptor: computational docking and molecular dynamics simulations S Paula, JR Baker, X Zhu, A McCluskey Molecular docking and molecular dynamics, 2019 | 5 | 2019 |
Recent developments in the use of flow hydrogenation in the field of medicinal chemistry CC Russell, JR Baker, PJ Cossar, A McCluskey New Advances in Hydrogenation Processes-Fundamentals and Applications, 2017 | 5 | 2017 |
A facile hybrid ‘flow and batch’access to substituted 3, 4-dihydro-2 H-benzo [b][1, 4] oxazinones AJS Lin, CC Russell, JR Baker, SL Frailey, JA Sakoff, A McCluskey Organic & Biomolecular Chemistry 14 (37), 8732-8742, 2016 | 5 | 2016 |