Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands S Morizane, K Yamasaki, B Mühleisen, PF Kotol, M Murakami, Y Aoyama, ... Journal of Investigative Dermatology 132 (1), 135-143, 2012 | 252 | 2012 |
Japanese guidelines for the management and treatment of generalized pustular psoriasis: the new pathogenesis and treatment of GPP H Fujita, T Terui, K Hayama, M Akiyama, S Ikeda, T Mabuchi, A Ozawa, ... The Journal of dermatology 45 (11), 1235-1270, 2018 | 224 | 2018 |
A mitotic cascade of NIMA family kinases: Nercc1/Nek9 activates the Nek6 and Nek7 kinases C Belham, J Roig, JA Caldwell, Y Aoyama, BE Kemp, M Comb, J Avruch Journal of Biological Chemistry 278 (37), 34897-34909, 2003 | 207 | 2003 |
Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell–cell adhesion E Calautti, M Grossi, C Mammucari, Y Aoyama, M Pirro, Y Ono, J Li, ... The Journal of cell biology 156 (1), 137-148, 2002 | 206 | 2002 |
Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human … Y Aoyama, Y Kitajima Journal of Investigative Dermatology 112 (1), 67-71, 1999 | 161 | 1999 |
A pathogenic autoantibody, pemphigus vulgaris‐IgG, induces phosphorylation of desmoglein 3, and its dissociation from plakoglobin in cultured keratinocytes Y Aoyama, MK Owada, Y Kitajima European journal of immunology 29 (7), 2233-2240, 1999 | 159 | 1999 |
IgG from patients with bullous pemphigoid depletes cultured keratinocytes of the 180-kDa bullous pemphigoid antigen (type XVII collagen) and weakens cell attachment H Iwata, N Kamio, Y Aoyama, Y Yamamoto, Y Hirako, K Owaribe, ... Journal of Investigative Dermatology 129 (4), 919-926, 2009 | 143 | 2009 |
Sequelae in 145 patients with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: survey conducted by the Asian Research Committee on … Y Kano, M Tohyama, M Aihara, S Matsukura, H Watanabe, H Sueki, ... The Journal of Dermatology 42 (3), 276-282, 2015 | 139 | 2015 |
Th2 cytokines increase kallikrein 7 expression and function in atopic dermatitis S Morizane, K Yamasaki, A Kajita, K Ikeda, M Zhan, Y Aoyama, RL Gallo, ... The Journal of allergy and clinical immunology 130 (1), 259, 2012 | 137 | 2012 |
Transmembrane signaling for adhesive regulation of desmosomes and hemidesmosomes, and for cell-cell detachment induced by pemphigus IgG in cultured keratinocytes: involvement … Y Kitajima, Y Aoyama, M Seishima Journal of investigative dermatology symposium proceedings 4 (2), 137-144, 1999 | 134 | 1999 |
Are desmoglein autoantibodies essential for the immunopathogenesis of pemphigus vulgaris, or just ‘witnesses of disease'? R Paus, M Amagai, AR Ahmed, Y Kitajima, JC Bystryn, Y Milner, ... Experimental dermatology 15 (10), 815-815, 2006 | 131 | 2006 |
Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases Y Aoyama, J Avruch, X Zhang Oncogene 23 (19), 3426-3433, 2004 | 126 | 2004 |
Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron … M Sato, Y Aoyama, Y Kitajima Laboratory investigation 80 (10), 1583-1592, 2000 | 106 | 2000 |
Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity Y Yamamoto, Y Aoyama, E Shu, K Tsunoda, M Amagai, Y Kitajima Journal of Biological Chemistry 282 (24), 17866-17876, 2007 | 100 | 2007 |
Methylprednisolone pulse therapy for Stevens-Johnson syndrome/toxic epidermal necrolysis: clinical evaluation and analysis of biomarkers K Hirahara, Y Kano, Y Sato, C Horie, A Okazaki, T Ishida, Y Aoyama, ... Journal of the American Academy of Dermatology 69 (3), 496-498, 2013 | 91 | 2013 |
Deformylation of 32-oxo-24, 25-dihydrolanosterol by the purified cytochrome P-45014DM (lanosterol 14 α-demethylase) from yeast evidence confirming the intermediate step of … Y Aoyama, Y Yoshida, Y Sonoda, Y Sato Journal of Biological Chemistry 264 (31), 18502-18505, 1989 | 90 | 1989 |
A randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoid M Amagai, S Ikeda, T Hashimoto, M Mizuashi, A Fujisawa, H Ihn, ... Journal of dermatological science 85 (2), 77-84, 2017 | 88 | 2017 |
Japanese guidelines for the management of pemphigus Committee for Guidelines for the Management of Pemphigus Disease, ... The Journal of dermatology 41 (6), 471-486, 2014 | 85 | 2014 |
Immune reconstitution inflammatory syndrome in non‐HIV immunosuppressed patients H Sueki, Y Mizukawa, Y Aoyama The Journal of Dermatology 45 (1), 3-9, 2018 | 83 | 2018 |
Pityriasis rubra pilaris type V as an autoinflammatory disease by CARD14 mutations T Takeichi, K Sugiura, T Nomura, T Sakamoto, Y Ogawa, N Oiso, Y Futei, ... JAMA dermatology 153 (1), 66-70, 2017 | 80 | 2017 |