Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc SK Madden, AD de Araujo, M Gerhardt, DP Fairlie, JM Mason Molecular Cancer 20 (1), 3, 2021 | 286 | 2021 |
Diels–Alder ligation and surface immobilization of proteins AD De Araújo, JM Palomo, J Cramer, M Köhn, H Schröder, R Wacker, ... Angewandte Chemie International Edition 45 (2), 296-301, 2006 | 201 | 2006 |
Comparative α‐Helicity of cyclic pentapeptides in water AD De Araujo, HN Hoang, WM Kok, F Diness, P Gupta, TA Hill, RW Driver, ... Angewandte Chemie International Edition 53 (27), 6965-6969, 2014 | 188 | 2014 |
Electrophilic Helical Peptides That Bond Covalently, Irreversibly, and Selectively in a Protein-Protein Interaction Site AD de Araujo, J Lim, AC Good, RT Skerlj, DP Fairlie ACS Medicinal Chemistry Letters 8 (1), 22-26, 2017 | 164* | 2017 |
Stapling peptides using cysteine crosslinking DP Fairlie, A Dantas de Araujo Peptide Science 106 (6), 843-852, 2016 | 135 | 2016 |
Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ... Nature communications 5 (1), 3165, 2014 | 133 | 2014 |
Modulating oxytocin activity and plasma stability by disulfide bond engineering M Muttenthaler, A Andersson, AD de Araujo, Z Dekan, RJ Lewis, ... Journal of medicinal chemistry 53 (24), 8585-8596, 2010 | 133 | 2010 |
Diels–Alder ligation of peptides and proteins AD de Araújo, JM Palomo, J Cramer, O Seitz, K Alexandrov, H Waldmann Chemistry–A European Journal 12 (23), 6095-6109, 2006 | 127 | 2006 |
Total synthesis of the analgesic conotoxin MrVIB through selenocysteine‐assisted folding AD de Araujo, B Callaghan, ST Nevin, NL Daly, DJ Craik, M Moretta, ... Angewandte Chemie International Edition 29 (50), 6527-6529, 2011 | 95 | 2011 |
Direct visualization of disulfide bonds through diselenide proxies using 77Se NMR spectroscopy. M Mobli, AD de Araújo, LK Lambert, GK Pierens, MJ Windley, ... Angewandte Chemie 121 (49), 9476-9478, 2009 | 62 | 2009 |
Bicyclic helical peptides as dual inhibitors selective for Bcl2A1 and Mcl-1 proteins A D. de Araujo, J Lim, KC Wu, Y Xiang, AC Good, R Skerlj, DP Fairlie Journal of medicinal chemistry 61 (7), 2962-2972, 2018 | 45 | 2018 |
Helix Nucleation by the Smallest Known α-Helix in Water HN Hoang, RW Driver, RL Beyer, TA Hill, A D de Araujo, F Plisson, ... Angewandte Chemie International Edition 55 (29), 8275-8279, 2016 | 43 | 2016 |
Cyclization of peptides by using selenolanthionine bridges AD de Araujo, M Mobli, GF King, PF Alewood Angewandte Chemie International Edition 41 (51), 10298-10302, 2012 | 42 | 2012 |
Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability SR Perry, TA Hill, AD de Araujo, HN Hoang, DP Fairlie Organic & biomolecular chemistry 16 (3), 367-371, 2018 | 31 | 2018 |
Development of cell‐penetrating peptide‐based drug leads to inhibit MDMX: p53 and MDM2: p53 interactions G Philippe, YH Huang, O Cheneval, N Lawrence, Z Zhang, DP Fairlie, ... Peptide Science 106 (6), 853-863, 2016 | 31 | 2016 |
Chemically diverse helix-constrained peptides using selenocysteine crosslinking A Dantas de Araujo, SR Perry, DP Fairlie Organic letters 20 (5), 1453-1456, 2018 | 27 | 2018 |
p‐Nitrobenzyl protection for cysteine and selenocysteine: A more stable alternative to the acetamidomethyl group M Muttenthaler, YG Ramos, D Feytens, AD de Araujo, PF Alewood Peptide Science 94 (4), 423-432, 2010 | 25 | 2010 |
A novel long‐range n to π* interaction secures the smallest known α‐helix in water HN Hoang, C Wu, TA Hill, A Dantas de Araujo, PV Bernhardt, L Liu, ... Angewandte Chemie International Edition 58 (52), 18873-18877, 2019 | 23 | 2019 |
Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling F Plisson, TA Hill, JM Mitchell, HN Hoang, AD de Araujo, W Xu, A Cotterell, ... European Journal of Medicinal Chemistry 127, 703-714, 2017 | 23 | 2017 |
Do vicinal disulfide bridges mediate functionally important redox transformations in proteins? AD de Araujo, V Herzig, MJ Windley, S Dziemborowicz, M Mobli, ... Antioxidants & redox signaling 19 (16), 1976-1980, 2013 | 20 | 2013 |