TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury S Balakrishna, W Song, S Achanta, SF Doran, B Liu, MM Kaelberer, Z Yu, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 307 (2 …, 2014 | 197 | 2014 |
Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death N Rimmerman, D Ben-Hail, Z Porat, A Juknat, E Kozela, MP Daniels, ... Cell death & disease 4 (12), e949-e949, 2013 | 175 | 2013 |
Chronic Adolescent Δ9-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by … M Murphy, S Mills, J Winstone, E Leishman, J Wager-Miller, H Bradshaw, ... Cannabis and cannabinoid research 2 (1), 235-246, 2017 | 122 | 2017 |
Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model of inflammation S Raboune, JM Stuart, E Leishman, SM Takacs, B Rhodes, A Basnet, ... Frontiers in cellular neuroscience 8, 195, 2014 | 117 | 2014 |
Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain E Leishman, K Mackie, S Luquet, HB Bradshaw Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 112 | 2016 |
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons LW Tung, GL Lu, YH Lee, L Yu, HJ Lee, E Leishman, H Bradshaw, ... Nature communications 7 (1), 12199, 2016 | 111 | 2016 |
Experimental colitis in mice is attenuated by changes in the levels of endocannabinoid metabolites induced by selective inhibition of fatty acid amide hydrolase (FAAH) M Sałaga, A Mokrowiecka, PK Zakrzewski, A Cygankiewicz, E Leishman, ... Journal of Crohn's and Colitis 8 (9), 998-1009, 2014 | 104 | 2014 |
Combinatory approaches prevent preterm birth profoundly exacerbated by gene-environment interactions J Cha, A Bartos, M Egashira, H Haraguchi, T Saito-Fujita, E Leishman, ... The Journal of clinical investigation 123 (9), 4063-4075, 2013 | 93 | 2013 |
Δ9-Tetrahydrocannabinol and cannabidiol differentially regulate intraocular pressure S Miller, L Daily, E Leishman, H Bradshaw, A Straiker Investigative ophthalmology & visual science 59 (15), 5904-5911, 2018 | 79 | 2018 |
Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice DJ Morgan, BJ Davis, CS Kearn, D Marcus, AJ Cook, J Wager-Miller, ... Journal of Neuroscience 34 (15), 5152-5163, 2014 | 75 | 2014 |
p53 coordinates decidual sestrin 2/AMPK/mTORC1 signaling to govern parturition timing W Deng, J Cha, J Yuan, H Haraguchi, A Bartos, E Leishman, B Viollet, ... The Journal of clinical investigation 126 (8), 2941-2954, 2016 | 74 | 2016 |
A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase LM Carey, RA Slivicki, E Leishman, B Cornett, K Mackie, H Bradshaw, ... Molecular pain 12, 1744806916649192, 2016 | 51 | 2016 |
Cannabidiol's Upregulation of N-acyl Ethanolamines in the Central Nervous System Requires N-acyl Phosphatidyl Ethanolamine-Specific Phospholipase D E Leishman, M Manchanda, R Thelen, S Miller, K Mackie, HB Bradshaw Cannabis and cannabinoid research 3 (1), 228-241, 2018 | 50 | 2018 |
Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the … E Leishman, B Cornett, K Spork, A Straiker, K Mackie, HB Bradshaw Pharmacological research 110, 159-172, 2016 | 48 | 2016 |
Chemotherapy‐induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol DI Brierley, JR Harman, N Giallourou, E Leishman, AE Roashan, ... Journal of Cachexia, Sarcopenia and Muscle 10 (4), 844-859, 2019 | 47 | 2019 |
Evidence for a GPR18 role in diurnal regulation of intraocular pressure S Miller, E Leishman, O Oehler, L Daily, N Murataeva, J Wager-Miller, ... Investigative ophthalmology & visual science 57 (14), 6419-6426, 2016 | 47 | 2016 |
Δ9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult E Leishman, M Murphy, K Mackie, HB Bradshaw Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 46 | 2018 |
Combined inhibition of monoacylglycerol lipase and cyclooxygenases synergistically reduces neuropathic pain in mice MS Crowe, E Leishman, ML Banks, R Gujjar, A Mahadevan, ... British journal of pharmacology 172 (7), 1700-1712, 2015 | 42 | 2015 |
Lipopolysaccharide-induced murine embryonic resorption involves changes in endocannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1 … ML Wolfson, F Correa, E Leishman, C Vercelli, C Cymeryng, J Blanco, ... Molecular and cellular endocrinology 411, 214-222, 2015 | 34 | 2015 |
Phencyclidine disrupts the auditory steady state response in rats E Leishman, BF O’Donnell, JB Millward, JL Vohs, O Rass, GP Krishnan, ... PLoS One 10 (8), e0134979, 2015 | 33 | 2015 |