| p53 is regulated by the lysine demethylase LSD1 J Huang, R Sengupta, AB Espejo, MG Lee, JA Dorsey, M Richter, ... Nature 449 (7158), 105-108, 2007 | 954 | 2007 |
| Repression of p53 activity by Smyd2-mediated methylation J Huang, L Perez-Burgos, BJ Placek, R Sengupta, M Richter, JA Dorsey, ... Nature 444 (7119), 629-632, 2006 | 755 | 2006 |
| Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth CHASLB Jiajun Zhu, Morgan A. Sammons, Greg Donahue, Zhixun Dou, Masoud ... Nature, 2015 | 497 | 2015 |
| G9a and Glp methylate lysine 373 in the tumor suppressor p53 J Huang, J Dorsey, S Chuikov, X Zhang, T Jenuwein, D Reinberg, ... Journal of Biological Chemistry 285 (13), 9636-9641, 2010 | 461 | 2010 |
| T cell stemness and dysfunction in tumors are triggered by a common mechanism SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ... Science 363 (6434), eaau0135, 2019 | 432 | 2019 |
| Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes J Yang, J Huang, M Dasgupta, N Sears, M Miyagi, B Wang, MR Chance, ... Proceedings of the National Academy of Sciences 107 (50), 21499-21504, 2010 | 361 | 2010 |
| The emerging field of dynamic lysine methylation of non-histone proteins J Huang, SL Berger Current opinion in genetics & development 18 (2), 152-158, 2008 | 341 | 2008 |
| Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells M Li, Y He, W Dubois, X Wu, J Shi, J Huang Molecular cell, 2012 | 312 | 2012 |
| The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression E Shema, I Tirosh, Y Aylon, J Huang, C Ye, N Moskovits, N Raver-Shapira, ... Genes & development 22 (19), 2664-2676, 2008 | 310 | 2008 |
| Single-chain estrogen receptors (ERs) reveal that the ERα/β heterodimer emulates functions of the ERα dimer in genomic estrogen signaling pathways X Li, J Huang, P Yi, RA Bambara, R Hilf, M Muyan Molecular and cellular biology, 2004 | 231 | 2004 |
| Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines F Liu, D Barsyte-Lovejoy, A Allali-Hassani, Y He, JM Herold, X Chen, ... Journal of medicinal chemistry 54 (17), 6139-6150, 2011 | 167 | 2011 |
| A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells KH Lee, M Li, AM Michalowski, X Zhang, H Liao, L Chen, Y Xu, X Wu, ... Proceedings of the National Academy of Sciences 107 (1), 69-74, 2010 | 160 | 2010 |
| The effects of estrogen-responsive element-and ligand-induced structural changes on the recruitment of cofactors and transcriptional responses by ERα and ERβ P Yi, MD Driscoll, J Huang, S Bhagat, R Hilf, RA Bambara, M Muyan Molecular Endocrinology 16 (4), 674-693, 2002 | 154 | 2002 |
| Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue J Shi, CN Marconett, J Duan, PL Hyland, P Li, Z Wang, W Wheeler, ... Nature communications 5 (1), 3365, 2014 | 153 | 2014 |
| Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1 J Huang, JR Kent, B Placek, KA Whelan, CM Hollow, PY Zeng, NW Fraser, ... Journal of virology 80 (12), 5740-5746, 2006 | 133 | 2006 |
| The histone variant H3. 3 regulates gene expression during lytic infection with herpes simplex virus type 1 BJ Placek, J Huang, JR Kent, J Dorsey, L Rice, NW Fraser, SL Berger Journal of virology 83 (3), 1416-1421, 2009 | 125 | 2009 |
| Direct regulation of alternative splicing by SMAD3 through PCBP1 is essential to the tumor-promoting role of TGF-β V Tripathi, KM Sixt, S Gao, X Xu, J Huang, R Weigert, M Zhou, YE Zhang Molecular cell 64 (3), 549-564, 2016 | 100 | 2016 |
| Current developments of targeting the p53 signaling pathway for cancer treatment J Huang Pharmacology & therapeutics 220, 107720, 2021 | 97 | 2021 |
| An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells M Li, H Gou, BK Tripathi, J Huang, S Jiang, W Dubois, T Waybright, M Lei, ... Cell Stem Cell, 2015 | 94 | 2015 |
| Targeting protein lysine methylation and demethylation in cancers Y He, I Korboukh, J Jin, J Huang Acta Biochim Biophys Sin 44 (1), 70-79, 2012 | 82 | 2012 |
Yunlong HeJohns Hopkins University, National Institutes of Health在 jhmi.edu 的电子邮件经过验证
