| Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27Kip1 H Kiyokawa, RD Kineman, KO Manova-Todorova, VC Soares, ... Cell 85 (5), 721-732, 1996 | 1537 | 1996 |
| Targeted disruption of CDK4 delays cell cycle entry with enhanced p27Kip1 activity T Tsutsui, B Hesabi, DS Moons, PP Pandolfi, KS Hansel, A Koff, ... Molecular and Cellular Biology 19 (10), 7011-7019, 1999 | 514 | 1999 |
| Requirement for CDK4 kinase function in breast cancer Q Yu, E Sicinska, Y Geng, M Ahnström, A Zagozdzon, Y Kong, H Gardner, ... Cancer cell 9 (1), 23-32, 2006 | 504 | 2006 |
| Cdc2–cyclin E complexes regulate the G1/S phase transition E Aleem, H Kiyokawa, P Kaldis Nature cell biology 7 (8), 831, 2005 | 492 | 2005 |
| The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. C Missero, F Di Cunto, H Kiyokawa, A Koff, GP Dotto Genes & development 10 (23), 3065-3075, 1996 | 391 | 1996 |
| The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration X Wang, H Kiyokawa, MB Dennewitz, RH Costa Proceedings of the National Academy of Sciences 99 (26), 16881-16886, 2002 | 374 | 2002 |
| Formation of p27-CDK complexes during the human mitotic cell cycle. TJ Soos, H Kiyokawa, JS Yan, MS Rubin, A Giordano, A DeBlasio, ... Cell growth & differentiation: the molecular biology journal of the American …, 1996 | 328 | 1996 |
| Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1 P Casaccia-Bonnefil, R Tikoo, H Kiyokawa, V Friedrich, MV Chao, A Koff Genes & development 11 (18), 2335-2346, 1997 | 315 | 1997 |
| Rapamycin resistance tied to defective regulation of p27Kip1. Y Luo, SO Marx, H Kiyokawa, A Koff, J Massagué, AR Marks Molecular and Cellular Biology 16 (12), 6744-6751, 1996 | 276 | 1996 |
| Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner JE Skeen, PT Bhaskar, CC Chen, WS Chen, X Peng, V Nogueira, ... Cancer cell 10 (4), 269-280, 2006 | 269 | 2006 |
| Enhanced ribosomal association of p27Kip1 mRNA is a mechanism contributing to accumulation during growth arrest SS Millard, JS Yan, H Nguyen, M Pagano, H Kiyokawa, A Koff Journal of Biological Chemistry 272 (11), 7093-7098, 1997 | 265 | 1997 |
| Akt induces β-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity S Fatrai, L Elghazi, N Balcazar, C Cras-Méneur, I Krits, H Kiyokawa, ... Diabetes 55 (2), 318-325, 2006 | 254 | 2006 |
| The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis K Krupczak-Hollis, X Wang, VV Kalinichenko, GA Gusarova, IC Wang, ... Developmental biology 276 (1), 74-88, 2004 | 246 | 2004 |
| Posttranslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism J Langenfeld, H Kiyokawa, D Sekula, J Boyle, E Dmitrovsky Proceedings of the National Academy of Sciences 94 (22), 12070-12074, 1997 | 246 | 1997 |
| Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation V Gandin, A Miluzio, AM Barbieri, A Beugnet, H Kiyokawa, PC Marchisio, ... Nature 455 (7213), 684, 2008 | 241 | 2008 |
| Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation C Berthet, KD Klarmann, MB Hilton, HC Suh, JR Keller, H Kiyokawa, ... Developmental cell 10 (5), 563-573, 2006 | 199 | 2006 |
| Cdk4 promotes adipogenesis through PPARγ activation A Abella, P Dubus, M Malumbres, SG Rane, H Kiyokawa, A Sicard, ... Cell metabolism 2 (4), 239-249, 2005 | 190 | 2005 |
| Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence X Zou, D Ray, A Aziyu, K Christov, AD Boiko, AV Gudkov, H Kiyokawa Genes & development 16 (22), 2923-2934, 2002 | 181 | 2002 |
| Myogenic hyperuricemia I Mineo, N Kono, N Hara, T Shimizu, Y Yamada, M Kawachi, H Kiyokawa, ... New England Journal of Medicine 317 (2), 75-80, 1987 | 169 | 1987 |
| Loss of cyclin-dependent kinase inhibitors produces adipocyte hyperplasia and obesity A Naaz, DR Holsberger, GA Iwamoto, A Nelson, H Kiyokawa, PS Cooke The FASEB journal 18 (15), 1925-1927, 2004 | 153 | 2004 |
