A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium W Checkley, AC White, D Jaganath, MJ Arrowood, RM Chalmers, ... The Lancet Infectious Diseases 15 (1), 85-94, 2015 | 951 | 2015 |
Cryptosporidiosis XM Chen, JS Keithly, CV Paya, NF LaRusso New England Journal of Medicine 346 (22), 1723-1731, 2002 | 764 | 2002 |
A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection XM Chen, PL Splinter, SP O'Hara, NF LaRusso Journal of Biological Chemistry 282 (39), 28929-28938, 2007 | 544 | 2007 |
Exosomal miRNAs: biological properties and therapeutic potential G Hu, KM Drescher, XM Chen Frontiers in genetics 3, 56, 2012 | 434 | 2012 |
Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-κB XM Chen, SP O’Hara, JB Nelson, PL Splinter, AJ Small, PS Tietz, ... The Journal of Immunology 175 (11), 7447-7456, 2005 | 255 | 2005 |
MicroRNA-513 regulates B7-H1 translation and is involved in IFN-γ-induced B7-H1 expression in cholangiocytes AY Gong, R Zhou, G Hu, X Li, PL Splinter, SP O'Hara, NF LaRusso, ... The Journal of Immunology 182 (3), 1325-1333, 2009 | 246 | 2009 |
NF-kappaB p65-Dependent Transactivation of miRNA Genes following Cryptosporidium parvum Infection Stimulates Epithelial Cell Immune Responses R Zhou, G Hu, J Liu, AY Gong, KM Drescher, XM Chen PLoS pathogens 5 (12), e1000681, 2009 | 243 | 2009 |
Long non-coding RNAs (lncRNAs) and their transcriptional control of inflammatory responses NW Mathy, XM Chen Journal of Biological Chemistry 292 (30), 12375-12382, 2017 | 240 | 2017 |
LincRNA-Cox2 promotes late inflammatory gene transcription in macrophages through modulating SWI/SNF-mediated chromatin remodeling G Hu, AY Gong, Y Wang, S Ma, X Chen, J Chen, CJ Su, A Shibata, ... The Journal of Immunology 196 (6), 2799-2808, 2016 | 223 | 2016 |
Binding of NF-kappaB p65 subunit to the promoter elements is involved in LPS-induced transactivation of miRNA genes in human biliary epithelial cells R Zhou, G Hu, AY Gong, XM Chen Nucleic acids research 38 (10), 3222-3232, 2010 | 221 | 2010 |
Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense G Hu, AY Gong, AL Roth, BQ Huang, HD Ward, G Zhu, NF LaRusso, ... PLoS pathogens 9 (4), e1003261, 2013 | 195 | 2013 |
MicroRNA signatures in liver diseases XM Chen World journal of gastroenterology: WJG 15 (14), 1665, 2009 | 173 | 2009 |
Cryptosporidium parvum activates nuclear factor κB in biliary epithelia preventing epithelial cell apoptosis XM Chen, SA Levine, PL Splinter, PS Tietz, AL Ganong, C Jobin, ... Gastroenterology 120 (7), 1774-1783, 2001 | 170 | 2001 |
Mechanisms of attachment and internalization of Cryptosporidium parvum to biliary and intestinal epithelial cells XM Chen, NF LaRusso Gastroenterology 118 (2), 368-379, 2000 | 151 | 2000 |
Cryptosporidium parvum induces apoptosis in biliary epithelia by a Fas/Fas ligand-dependent mechanism XM Chen, GJ Gores, CV Paya, NF LaRusso American Journal of Physiology-Gastrointestinal and Liver Physiology 277 (3 …, 1999 | 145 | 1999 |
Agonist-induced coordinated trafficking of functionally related transport proteins for water and ions in cholangiocytes PS Tietz, RA Marinelli, XM Chen, B Huang, J Cohn, J Kole, MA McNiven, ... Journal of Biological Chemistry 278 (22), 20413-20419, 2003 | 142 | 2003 |
MicroRNA regulation of innate immune responses in epithelial cells R Zhou, SP O'hara, XM Chen Cellular & molecular immunology 8 (5), 371-379, 2011 | 140 | 2011 |
Faecalibacterium prausnitzii‐derived microbial anti‐inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction … J Xu, R Liang, W Zhang, K Tian, J Li, X Chen, T Yu, Q Chen Journal of diabetes 12 (3), 224-236, 2020 | 138 | 2020 |
The cell biology of Cryptosporidium infection SP O’Hara, XM Chen Microbes and infection 13 (8-9), 721-730, 2011 | 137 | 2011 |
MicroRNA-98 and let-7 confer cholangiocyte expression of cytokine-inducible Src homology 2-containing protein in response to microbial challenge G Hu, R Zhou, J Liu, AY Gong, AN Eischeid, JW Dittman, XM Chen The Journal of Immunology 183 (3), 1617-1624, 2009 | 137 | 2009 |