Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease S Kriks, JW Shim, J Piao, YM Ganat, DR Wakeman, Z Xie, L Carrillo-Reid, ... Nature 480 (7378), 547-551, 2011 | 2109 | 2011 |
Human iPSC-based modeling of late-onset disease via progerin-induced aging JD Miller, YM Ganat, S Kishinevsky, RL Bowman, B Liu, EY Tu, ... Cell stem cell 13 (6), 691-705, 2013 | 807 | 2013 |
Oxidative stress and cellular pathologies in Parkinson’s disease L Puspita, SY Chung, J Shim Molecular brain 10, 1-12, 2017 | 473 | 2017 |
In vitro and in vivo analyses of human embryonic stem cell‐derived dopamine neurons CH Park, YK Minn, JY Lee, DH Choi, MY Chang, JW Shim, JY Ko, HC Koh, ... Journal of neurochemistry 92 (5), 1265-1276, 2005 | 354 | 2005 |
Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease YH Rhee, JY Ko, MY Chang, SH Yi, D Kim, CH Kim, JW Shim, AY Jo, ... The Journal of clinical investigation 121 (6), 2326-2335, 2011 | 308 | 2011 |
Parkin and PINK1 patient iPSC-derived midbrain dopamine neurons exhibit mitochondrial dysfunction and α-synuclein accumulation SY Chung, S Kishinevsky, JR Mazzulli, J Graziotto, A Mrejeru, ... Stem cell reports 7 (4), 664-677, 2016 | 215 | 2016 |
Loss of SATB1 induces p21-dependent cellular senescence in post-mitotic dopaminergic neurons M Riessland, B Kolisnyk, TW Kim, J Cheng, J Ni, JA Pearson, EJ Park, ... Cell stem cell 25 (4), 514-530. e8, 2019 | 129 | 2019 |
Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival HS Lee, EJ Bae, SH Yi, JW Shim, AY Jo, JS Kang, EH Yoon, YH Rhee, ... Stem cells 28 (3), 501-512, 2010 | 129 | 2010 |
Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells … JW Shim, HC Koh, MY Chang, E Roh, CY Choi, YJ Oh, H Son, YS Lee, ... Journal of Neuroscience 24 (4), 843-852, 2004 | 127 | 2004 |
Generation of functional dopamine neurons from neural precursor cells isolated from the subventricular zone and white matter of the adult rat brain using Nurr1 overexpression JW Shim, CH Park, YC Bae, JY Bae, S Chung, MY Chang, HC Koh, ... Stem cells 25 (5), 1252-1262, 2007 | 124 | 2007 |
Basic fibroblast growth factor promotes bone marrow stromal cell transplantation-mediated neural regeneration in traumatic brain injury SH Bhang, YE Lee, SW Cho, JW Shim, SH Lee, CY Choi, JW Chang, ... Biochemical and Biophysical Research Communications 359 (1), 40-45, 2007 | 108 | 2007 |
Microbial metabolites determine host health and the status of some diseases P Sittipo, J Shim, YK Lee International journal of molecular sciences 20 (21), 5296, 2019 | 107 | 2019 |
Comprehensive transcriptome analysis of differentiation of embryonic stem cells into midbrain and hindbrain neurons JI Ahn, KH Lee, DM Shin, JW Shim, JS Lee, SY Chang, YS Lee, ... Developmental biology 265 (2), 491-501, 2004 | 62 | 2004 |
Bcl-XL/Bax Proteins Direct the Fate of Embryonic Cortical Precursor Cells MY Chang, W Sun, W Ochiai, K Nakashima, SY Kim, CH Park, JS Kang, ... Molecular and cellular biology 27 (12), 4293-4305, 2007 | 53 | 2007 |
Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro CH Park, JS Kang, EH Yoon, JW Shim, H Suh-Kim, SH Lee FEBS letters 582 (5), 537-542, 2008 | 52 | 2008 |
Generation of caudal-type serotonin neurons and hindbrain-fate organoids from hPSCs P Valiulahi, V Vidyawan, L Puspita, Y Oh, VB Juwono, P Sittipo, ... Stem Cell Reports 16 (8), 1938-1952, 2021 | 42 | 2021 |
Co-transfection with cDNA encoding the Bcl family of anti-apoptotic proteins improves the efficiency of transfection in primary fetal neural stem cells YC Kim, JW Shim, YJ Oh, H Son, YS Lee, SH Lee Journal of neuroscience methods 117 (2), 153-158, 2002 | 32 | 2002 |
Floor plate-derived dopamine neurons from hESCs efficiently engraft in animal models of PD S Kriks, JW Shim, J Piao, YM Ganat, DR Wakeman, Z Xie, L Carrillo-Reid, ... Nature 480 (7378), 547, 2011 | 31 | 2011 |
In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns T Kim, JJ Song, L Puspita, P Valiulahi, J Shim, SH Lee Experimental & Molecular Medicine 49 (3), e300-e300, 2017 | 25 | 2017 |
In vitro generation of mature dopamine neurons by decreasing and delaying the expression of exogenous Nurr1 CH Park, MS Lim, YH Rhee, SH Yi, BK Kim, JW Shim, YH Kim, SJ Jung, ... Development 139 (13), 2447-2451, 2012 | 22 | 2012 |