Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth L Zhang, S Zhang, J Yao, FJ Lowery, Q Zhang, WC Huang, P Li, M Li, ... Nature 527 (7576), 100-104, 2015 | 1183 | 2015 |
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer K Michailidou, J Beesley, S Lindstrom, S Canisius, J Dennis, MJ Lush, ... Nature genetics 47 (4), 373-380, 2015 | 660 | 2015 |
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche JRB Perry, F Day, CE Elks, P Sulem, DJ Thompson, T Ferreira, C He, ... Nature 514 (7520), 92-97, 2014 | 607 | 2014 |
Identification of six new susceptibility loci for invasive epithelial ovarian cancer KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ... Nature genetics 47 (2), 164-171, 2015 | 310 | 2015 |
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes L Fachal, H Aschard, J Beesley, DR Barnes, J Allen, S Kar, KA Pooley, ... Nature genetics 52 (1), 56-73, 2020 | 157 | 2020 |
Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance JM Saunus, MCJ Quinn, AM Patch, JV Pearson, PJ Bailey, K Nones, ... The Journal of pathology 237 (3), 363-378, 2015 | 120 | 2015 |
Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer F Al-Ejeh, PT Simpson, JM Sanus, K Klein, M Kalimutho, W Shi, ... Oncogenesis 3 (4), e100-e100, 2014 | 108 | 2014 |
Heritable DNA methylation marks associated with susceptibility to breast cancer JE Joo, JG Dowty, RL Milne, EM Wong, PA Dugué, D English, JL Hopper, ... Nature communications 9 (1), 867, 2018 | 101 | 2018 |
In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity CE Smart, BJ Morrison, JM Saunus, AC Vargas, P Keith, L Reid, ... PLoS One 8 (6), e64388, 2013 | 92 | 2013 |
Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implications AE McCart Reed, E Kalaw, K Nones, M Bettington, M Lim, J Bennett, ... The Journal of pathology 247 (2), 214-227, 2019 | 84 | 2019 |
Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers I Blanco, K Kuchenbaecker, D Cuadras, X Wang, D Barrowdale, ... PLoS One 10 (4), e0120020, 2015 | 79 | 2015 |
Calcium signalling and breast cancer CL So, JM Saunus, SJ Roberts-Thomson, GR Monteith Seminars in Cell & Developmental Biology 94, 74-83, 2019 | 77 | 2019 |
The calcium pump plasma membrane Ca2+-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin AA Peters, MJG Milevskiy, WC Lee, MC Curry, CE Smart, JM Saunus, ... Scientific reports 6 (1), 25505, 2016 | 77 | 2016 |
Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases L Zhang, J Yao, Y Wei, Z Zhou, P Li, J Qu, A Badu-Nkansah, X Yuan, ... Science translational medicine 12 (545), eaaz5387, 2020 | 74 | 2020 |
Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines M Momeny, JM Saunus, F Marturana, AEMC Reed, D Black, G Sala, ... Oncotarget 6 (6), 3932, 2015 | 74 | 2015 |
CEP 55 is a determinant of cell fate during perturbed mitosis in breast cancer M Kalimutho, D Sinha, J Jeffery, K Nones, S Srihari, WC Fernando, ... EMBO molecular medicine 10 (9), e8566, 2018 | 71 | 2018 |
Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer MJG Milevskiy, F Al-Ejeh, JM Saunus, KS Northwood, PJ Bailey, JA Betts, ... Human molecular genetics 25 (15), 3269-3283, 2016 | 69 | 2016 |
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype S Junankar, LA Baker, DL Roden, R Nair, B Elsworth, D Gallego-Ortega, ... Nature communications 6 (1), 6548, 2015 | 61 | 2015 |
Molecular classification of breast carcinoma M Alizart, J Saunus, M Cummings, SR Lakhani Diagnostic Histopathology 18 (3), 97-103, 2012 | 61 | 2012 |
Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR JM Saunus, JD French, SL Edwards, DJ Beveridge, EC Hatchell, ... Cancer research 68 (22), 9469-9478, 2008 | 61 | 2008 |