Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model K Nakamura, Y Ito, Y Kawano, K Kurozumi, M Kobune, H Tsuda, A Bizen, ... Gene therapy 11 (14), 1155-1164, 2004 | 812 | 2004 |
Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model K Kurozumi, K Nakamura, T Tamiya, Y Kawano, K Ishii, M Kobune, S Hirai, ... Molecular Therapy 11 (1), 96-104, 2005 | 548 | 2005 |
BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model K Kurozumi, K Nakamura, T Tamiya, Y Kawano, M Kobune, S Hirai, ... Molecular Therapy 9 (2), 189-197, 2004 | 488 | 2004 |
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses G Fulci, L Breymann, D Gianni, K Kurozomi, SS Rhee, J Yu, B Kaur, ... Proceedings of the National Academy of Sciences 103 (34), 12873-12878, 2006 | 402 | 2006 |
Angiogenesis and invasion in glioma M Onishi, T Ichikawa, K Kurozumi, I Date Brain tumor pathology 28, 13-24, 2011 | 350 | 2011 |
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy K Kurozumi, J Hardcastle, R Thakur, M Yang, G Christoforidis, G Fulci, ... Journal of the National Cancer Institute 99 (23), 1768-1781, 2007 | 206 | 2007 |
Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses A Otsuki, A Patel, K Kasai, M Suzuki, K Kurozumi, EA Chiocca, Y Saeki Molecular Therapy 16 (9), 1546-1555, 2008 | 193 | 2008 |
Serine/threonine kinase MLK4 determines mesenchymal identity in glioma stem cells in an NF-κB-dependent manner SH Kim, R Ezhilarasan, E Phillips, D Gallego-Perez, A Sparks, D Taylor, ... Cancer cell 29 (2), 201-213, 2016 | 165 | 2016 |
Embryonic neural stem cells transplanted in middle cerebral artery occlusion model of rats demonstrated potent therapeutic effects, compared to adult neural stem cells K Takahashi, T Yasuhara, T Shingo, K Muraoka, M Kameda, A Takeuchi, ... Brain research 1234, 172-182, 2008 | 119 | 2008 |
Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1 J Hardcastle, K Kurozumi, N Dmitrieva, MP Sayers, S Ahmad, ... Molecular Therapy 18 (2), 285-294, 2010 | 118 | 2010 |
Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging MLM Lamfers, G Fulci, D Gianni, Y Tang, K Kurozumi, B Kaur, ... Molecular Therapy 14 (6), 779-788, 2006 | 108 | 2006 |
The relationship between peritumoral brain edema and the expression of vascular endothelial growth factor and its receptors in intracranial meningiomas S Otsuka, T Tamiya, Y Ono, H Michiue, K Kurozumi, S Daido, H Kambara, ... Journal of neuro-oncology 70, 349-357, 2004 | 105 | 2004 |
Adult neural stem and progenitor cells modified to secrete GDNF can protect, migrate and integrate after intracerebral transplantation in rats with transient forebrain ischemia M Kameda, T Shingo, K Takahashi, K Muraoka, K Kurozumi, T Yasuhara, ... European Journal of Neuroscience 26 (6), 1462-1478, 2007 | 103 | 2007 |
Therapeutic effect of suicide gene-transferred mesenchymal stem cells in a rat model of glioma H Kosaka, T Ichikawa, K Kurozumi, H Kambara, S Inoue, T Maruo, ... Cancer gene therapy 19 (8), 572-578, 2012 | 99 | 2012 |
Integrated clinical, histopathological, and molecular data analysis of 190 central nervous system germ cell tumors from the iGCT Consortium H Takami, K Fukuoka, S Fukushima, T Nakamura, A Mukasa, N Saito, ... Neuro-oncology 21 (12), 1565-1577, 2019 | 93 | 2019 |
Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors K Fukuoka, Y Kanemura, T Shofuda, S Fukushima, S Yamashita, ... Acta neuropathologica communications 6, 1-18, 2018 | 92 | 2018 |
Oncolytic HSV-1 infection of tumors induces angiogenesis and upregulates CYR61 K Kurozumi, J Hardcastle, R Thakur, J Shroll, M Nowicki, A Otsuki, ... Molecular Therapy 16 (8), 1382-1391, 2008 | 90 | 2008 |
Apoptosis induction with 5-fluorocytosine/cytosine deaminase gene therapy for human malignant glioma cells mediated by adenovirus K Kurozumi, T Tamiya, Y Ono, S Otsuka, H Kambara, Y Adachi, ... Journal of neuro-oncology 66, 117-127, 2004 | 81 | 2004 |
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas S Fukushima, S Yamashita, H Kobayashi, H Takami, K Fukuoka, ... Acta neuropathologica 133, 445-462, 2017 | 78 | 2017 |
Oncolytic viruses driven by tumor-specific promoters J Hardcastle, K Kurozumi, E Antonio Chiocca, B Kaur Current cancer drug targets 7 (2), 181-189, 2007 | 75 | 2007 |